{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T05:32:02Z","timestamp":1791955922292,"version":"4.3.4"},"reference-count":15,"publisher":"Universa BV","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2021,6]]},"abstract":"Acute pancreatitis (AP) is an inflammatory process of the pancreas. It is a relatively common cause of acute upper abdominal pain and is potentially associated with high morbidity and mortality. Underlying hypercalcemia as a cause of AP is very rare. We present a case of a hypercalcemia-induced acute pancreatitis with an underlying parathyroid adenoma in an 81-year-old woman with no previous symptoms of hypercalcemia. The parathyroid adenoma was semi-urgently surgically resected with normalization of calcium-levels. This case report summarizes the causes of acute pancreatitis and hypercalcemia and its management.<\/jats:p>","DOI":"10.51821\/84.2.367","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:01:53Z","timestamp":1627603313000},"page":"367-370","source":"Crossref","is-referenced-by-count":6,"title":["Hypercalcemia induced pancreatitis as a rare presentation of primary hyperparathyroidism"],"prefix":"10.51821","volume":"84","author":[{"given":"V","family":"Desmedt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Desmedt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"D\u2019heygere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Vereecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Van Moerkercke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27062","published-online":{"date-parts":[[2021,6]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"FROSSARD J.L., STEER M.L., PASTOR C.M. Acute pancreatitis. The Lancet. 2008, 371 : 143-152.","DOI":"10.1016\/s0140-6736(08)60107-5"},{"key":"ref1","unstructured":"VAN WOERKOM R.C., ADLER D.G. Acute Pancreatitis : Review and Clinical Update. Hospital Physician. 2009, 45 : 9-19."},{"key":"ref2","unstructured":"ABDULLAH M. Pancreatitis in primary hyperparathyroidism. Med. J Malaysia. 2003, 58 : 600-3."},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"SPANIER B., BRUNO M.J., DIJKGRAAF M.G. Incidence and mortality of acute and chronic pancreatitis in the Netherlands : a nationwide record-linked cohort study for the years 1995-2005. World J. Gastroenterol. 2013, 19 : 3018-3026.","DOI":"10.3748\/wjg.v19.i20.3018"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"MISGAR R.A., BHAT M.H., RATHER T.A., MASOODI S.R., WANI A.I., BASHIR M.I. et al. Primary hyperparathyroidism and pancreatitis. J. Endocrinol. Invest. 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Epidemiology of primary hyperparathyroidism in Europe. J. Bone Miner. Res. 2002, 17 Suppl 2 : N18-23."},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"TURNER J.J.O. Hypercalcaemia - presentation and management. Clin. Med. (Lond). 2017, 17 : 270-273.","DOI":"10.7861\/clinmedicine.17-3-270"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"INSOGNA K.L. Primary Hyperparathyroidism. N. Engl. J. Med. 2018, 379 : 1050-1059.","DOI":"10.1056\/NEJMcp1714213"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"WALKER M.D., SILVERBERG S.J. Primary hyperparathyroidism. Nat. Rev. Endocrinol. 2018, 14 : 115-125.","DOI":"10.1038\/nrendo.2017.104"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"BILEZIKIAN J.P., CUSANO N.E., KHAN A.A., LIU J.M., MARCOCCI C., BANDEIRA F. Primary hyperparathyroidism. Nat. Rev. Dis. Primers. 2016, 2 : 16033.","DOI":"10.1038\/nrdp.2016.33"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"GRIEFF M., BUSHINSKY D. Diuretics and disorders of calcium homeo-stasis. Semin. Nephrol. 2011, 31 : 535-54.","DOI":"10.1016\/j.semnephrol.2011.09.008"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"GRIBELER M.L., KEARNS A.E., RYU E., THAPA P., HATHCOCK M.A., MELTON L.J. et al. Thiazide-Associated Hypercalcemia: Incidence and Association With Primary Hyperparathyroidism Over Two Decades. J. Clin. Endocrinol. 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