{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T08:38:57Z","timestamp":1672648737624},"reference-count":15,"publisher":"Universa BV","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Cerebral abscess formation is a serious and life-threatening clinical entity, secondary to contiguous spread, hematogenous dissemination or direct inoculation. We present the case of a 61-year-old woman with a recent diagnosis of a locally advanced squamous cell carcinoma of the esophagus who was diagnosed with a brainstem abscess. In literature we only found three cases reporting cerebral abscess formation in patients with esophageal carcinoma. Our case report is considered exceptional given the abscess localization in the pons. The abscess was successfully treated with stereotactic drainage and antibiotics. This report emphasizes the importance of gastrointestinal tract evaluation in patients with diagnosis of cerebral abscess when no other cause is found. Brain abscesses must be recognized as a potentially fatal complication of esophageal carcinoma.<\/jats:p>","DOI":"10.51821\/85.1.8442","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T20:45:37Z","timestamp":1647377137000},"page":"105-107","source":"Crossref","is-referenced-by-count":1,"title":["Esophageal carcinoma as a portal of entry for brainstem abscess formation"],"prefix":"10.51821","volume":"85","author":[{"given":"P","family":"Corens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Lamquet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Vanderstraeten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"De Vlieger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"De Cocker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Monsaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Bouderez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Vandekerckhove","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"van Steenkiste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27062","published-online":{"date-parts":[[2022,3]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"HELWEG-LARSEN J, ARSTRADSSON A, RICHHALL H, ERDAL J, LAURSEN A, BRENNUM J. Pyogenic brain abscess, a 15 year survey. BMC Infectious Diseases, 2012, 12: 332-42.","DOI":"10.1186\/1471-2334-12-332"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"BROUWER M, COUTINHO J, VAN DE BEEK D. Clinical characteristics and outcome of brain abscess: systematic review and meta-analysis. Neurology, 2014, 82: 806-13.","DOI":"10.1212\/wnl.0000000000000172"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"GAINI S, GRAND M, MICHELSEN J. Brain Abscess after Esophageal Dilatation: Case Report. Infection, 2008, 36: 71-3.","DOI":"10.1007\/s15010-007-6223-8"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"ALGOED L, BOON P, DE VOS M, VAN DEN ABEELE K, SANTENS P, DE REUCK J, et al. Brain abscess after esophageal dilatation for stenosis. Clinical Neurology and Neurosurgery, 1992, 94: 169-72.","DOI":"10.1016\/0303-8467(92)90077-g"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"VAN EVEN E, BOEL A, VAN VAERENBERGH K, DE BEENHOUWER H. Brain abscesses with peptostreptococcus: not unusual after oesophageal dilatation. Acta Clinica Belgica, 2012, 67(4): 292-4.","DOI":"10.1179\/2295333714y.0000000111"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"COHEN F, KOERNER R, TAUB S. Solitary brain abscess following endoscopic injection sclerosis of esophageal varices. Gastrointest. Endosc., 1985, 31(5): 331-3.","DOI":"10.1016\/s0016-5107(85)72217-1"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"SHIH H, LEE H, CHUANG C, KO W. Fatal Klebsiella pneumoniae meningitis and emphysematous brain abscess after endoscopic variceal ligation in a patient with liver cirrhosis and diabetes mellitus. J. Formos. Med. Assoc., 2006, 105(10): 857-60.","DOI":"10.1016\/s0929-6646(09)60275-8"},{"key":"ref7","unstructured":"WANG W, CHEN C, JAN C. Central nervous system infection after endoscopic injection sclerotherapy. Am. J. Gastroenterol., 1990, 85(7): 865-7."},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"LOUIE J, OSTERHOUDT K, CHRISTIAN C. Brain abscess following delayed endoscopic removal of an initially asymptomatic esophageal coin. Pediatr. Emerg. Care., 2000, 16: 102-5.","DOI":"10.1097\/00006565-200004000-00011"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"HANNA M, DAS D. Oesophageal adenocarcinoma presenting with multiple Streptococcus intermedius cerebral abscesses. J. Gastrointest. Cancer., 2014, 45: 18-21.","DOI":"10.1007\/s12029-013-9522-6"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"MACKAY C, CHEN Y. Ruptured cerebral abscess with ventriculitis and leptomeningitis; A rare complication in the setting of metastatic esophageal cancer: case report and literature review. Radiology Case Reports, 2019, 14: 782-5.","DOI":"10.1016\/j.radcr.2019.03.034"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"NAYFE R, ASCHA M, REHMUS E. Esophageal Squamous Cell Carcinoma Presenting with Streptococcus intermedius Cerebral abscess. Case Rep. Pathol., 2017, 2017: 5819676.","DOI":"10.1155\/2017\/5819676"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"NELSON D. Infectious disease complications of GI endoscopy: Part I, endogenous infections. Gastrointest. Endosc., 2003, 57: 546-56.","DOI":"10.1067\/mge.2003.139"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"REY J, AXON A, BUDZYNSKA AK, A., NOWAK A. Guidelines of the European Society of Gastrointestinal Endoscopy (E.S.G.E.) Antibiotic Prophylaxis for Gastrointestinal Endoscopy. Endoscopy, 1998, 30: 318-24.","DOI":"10.1016\/s0016-5107(95)70032-3"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"BATSON O. The Function of the vertrebral veins and their role in the spread of metastases. Ann. 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