{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T20:14:58Z","timestamp":1762460098959},"reference-count":33,"publisher":"Universa BV","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AGEB"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:p>Background and study aims: Small-bowel capsule endoscopy (SBCE) is a safe and efficient method for diagnosis of small-bowel diseases. Since its development, different models have appeared. The aim of this study was to analyze which of the different models of SBCE has the best diagnostic yield.\n\nPatients and methods: Extensive medical literature research was reviewed, using MESH terms, searching studies comparing different SBCE types. We analyzed the diagnostic yield of all the comparisons and when there were 2 or more studies that compared the same model of SBCEs, a meta-analysis was performed.\n\nResults: Ten eligible studies including 1065 SBCEs procedures were identified. The main indication was occult gastrointestinal bleeding in 9\/10 studies. Two of them included anemia, chronic diarrhea and\/or chronic abdominal pain. The indication in one article was celiac disease. In 9 studies, different types of SBCEs (MiroCam, Endocapsule, OMOM and CapsoCam) were compared with PillCam (SB, SB2 and SB3). Three studies compared MiroCam vs PillCam and CapsoCam vs PillCam, while two studies contrast Endocapsule vs PillCam. None of the SBCEs show superiority over PillCam [OR 0.78 (95%CI;0.60-1.01)]. One study compared SBCEs other than Pillcam (MiroCam vs Endocapsule). Nine studies did not find statistical differences between SBCEs, one showed better diagnostic yield of Mirocam compared with PillCam SB3 (p=0.02). The difference between these SBCE was not replayed in the metaanalysis [OR 0.77 (95%CI;0.49-1.21)].\n\nConclusions: Despite the appearance of new SBCE models, there are no differences in diagnostic yield; therefore, SBCE endoscopist\u2019s performance should be based on experience and availability.<\/jats:p>","DOI":"10.51821\/85.3.10322","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T22:13:16Z","timestamp":1668118396000},"page":"509-517","source":"Crossref","is-referenced-by-count":12,"title":["Which model of small bowel capsule endoscopy has a better diagnostic yield? A systematic review and meta-analysis"],"prefix":"10.51821","volume":"85","author":[{"given":"G","family":"Blanco-Velasco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.V.","family":"Hern\u00e1ndez-Mondrag\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.M.","family":"Sol\u00f3rzano-Pineda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.F.","family":"Garc\u00eda-Contreras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Mart\u00ednez-Camacho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Murcio-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27062","published-online":{"date-parts":[[2022,9]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"KOULAOUZIDIS A, RONDONOTTI E, KARARGYRIS A. Small-bowel capsule endoscopy: a ten-point contemporary review. World J Gastroenterol 2013;19:3726-3746.","DOI":"10.3748\/wjg.v19.i24.3726"},{"key":"ref1","doi-asserted-by":"crossref","unstructured":"ADLER SN. The history of time for capsule endoscopy. Ann Transl Med 2017;5:194.","DOI":"10.21037\/atm.2017.03.90"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"IDDAN G, MERON G, GLUKHOVSKY A, SWAIN P. Wireless capsule endoscopy. Nature 2000;405:417.","DOI":"10.1038\/35013140"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"CHING HL, MCALINDON ME, SIDHU R. An update on small bowel endoscopy. Curr Opin Gastroenterol 2017;33:181-188.","DOI":"10.1097\/MOG.0000000000000346"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"ELIAKIM R. Where do I see minimally invasive endoscopy in 2020: clock is ticking. Ann Transl Med 2017;5:202","DOI":"10.21037\/atm.2017.04.17"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"PIOCHE M, VANBIERVLIET G, JACOB P, DUBURQUE C, GINCUL R, FILOCHE B, et al. Prospective randomized comparison between axial- and lateral-viewing capsule endoscopy systems in patients with obscure digestive bleeding. Endoscopy 2014;46:479-484.","DOI":"10.1055\/s-0033-1358832"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"BLANCO-VELASCO G, ZAMARRIPA-MOTT\u00da RA, SOL\u00d3RZANO-PINEDA OM, MASCARENHAS-SARAIVA M, BLANCAS-VALENCIA JM, HERN\u00c1NDEZ-MONDRAG\u00d3N OV. Comparison in the diagnostic yield between \u201cPillcam SB3\u201d capsule endoscopy and \u201cOMOM Smart Capsule 2\u201d in small bowel bleeding: A randomized head-to-head study. Dig Dis. 2021; 39:211-216.","DOI":"10.1159\/000511958"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"MERON GD. The development of the swallowable video capsule (M2A). Gastrointest Endosc 2000;52:817-819.","DOI":"10.1067\/mge.2000.110204"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"HOSOE N, TAKABAYASHI K, OGATA H, KANAI T. Capsule endoscopy for small-intestinal disorders: Current status. Dig Endosc 2019;31:498-507.","DOI":"10.1111\/den.13346"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"BLANCO-VELASCO G, SOL\u00d3RZANO-PINEDA OM, MENDOZA-SEGURA C, HERN\u00c1NDEZ-MONDRAG\u00d3N O. PillCam SB3 vs. PillCam SB2: Can technologic advances in capsule endoscopy improve diagnostic yield in patients with small bowel bleeding? Rev Gastroenterol Mex 2019; 84:467-471.","DOI":"10.1016\/j.rgmxen.2018.11.006"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"XAVIER S, MONTEIRO S, MAGALH\u00c3ES J, ROSA B, MOREIRA MJ, COTTER J. Capsule endoscopy with PillCamSB2 versus PillCamSB3: has the improvement in technology resulted in a step forward? Rev Esp Enferm Dig 2018;110:155-159.","DOI":"10.17235\/reed.2017.5071\/2017"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"D\u2019HALLUIN PN, DELVAUX M, LAPALUS MG, SACHER-HUVELIN S, SOUSSAN EB, HEYRIES L, et al. Does the \u201cSuspected Blood Indicator\u201d improve the detection of bleeding lesions by capsule endoscopy? Gastrointest Endosc 2005;61:243-249.","DOI":"10.1016\/s0016-5107(04)02587-8"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"ABDELAAL UM, MORITA E, NOUDA S, KURAMOTO T, MIYAJI K, FUKUI H, et al. Blue mode imaging may improve the detection and visualization of small-bowel lesions: A capsule endoscopy study. Saudi J Gastroenterol 2015;21:418-422.","DOI":"10.4103\/1319-3767.170954"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"KOULAOUZIDIS A, SMIRNIDIS A, DOUGLAS S, PLEVRIS JN. QuickView in small-bowel capsule endoscopy is useful in certain clinical settings, but QuickView with Blue Mode is of no additional benefit. Eur J Gastroenterol Hepatol 2012;24:1099-1104.","DOI":"10.1097\/meg.0b013e32835563ab"},{"key":"ref14","unstructured":"GHEORGHE C, IACOB R, BANCILA I. Olympus capsule endoscopy for small bowel examination. J Gastrointestin Liver Dis 2007;16:309-313."},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"HOSOE N, NAGANUMA M, OGATA H. Current status of capsule endoscopy through a whole digestive tract. Dig Endosc 2015;27:205-215.","DOI":"10.1111\/den.12380"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"BEG S, WRONSKA E, ARAUJO I, GONZ\u00c1LEZ SU\u00c1REZ B, IVANOVA E. Use of rapid reading software to reduce capsule endoscopy reading times while maintaining accuracy. Gastrointest Endosc 2020;91:1322-1327.","DOI":"10.1016\/j.gie.2020.01.026"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"BANG S, PARK JY, JEONG S, KIM YH, SHIM HB, KIM TS, et al. First clinical trial of the \u201cMiRo\u201d capsule endoscope by using a novel transmission technology: electric-field propagation. Gastrointest Endosc 2009;69:253-259.","DOI":"10.1016\/j.gie.2008.04.033"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"GOMES C, PINHO R, PONTE A, RODRIGUES A, SOUSA M, SILVA JC, et al. Evaluation of the sensitivity of the Express View function in the Mirocam \u00ae capsule endoscopy software. Scand J Gastroenterol 2020;55:371-375.","DOI":"10.1080\/00365521.2020.1734650"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"ZHANG L, SHEN J, GUO L, CHANG F, FAN Q, NI K, et al. Diagnostic value of OMOM capsule endoscopy for small bowel diseases in adults. Exp Ther Med 2018;15:3467-3470.","DOI":"10.3892\/etm.2018.5864"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"FRIEDRICH K, GEHRKE S, STREMMEL W, SIEG A. First clinical trial of a newly developed capsule endoscope with panoramic side view for small bowel: a pilot study. J Gastroenterol Hepatol 2013;28:1496-1501.","DOI":"10.1111\/jgh.12280"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"HARTMANN D, EICKHOFF A, DAMIAN U, RIEMANN JF. Diagnosis of small-bowel pathology using paired capsule endoscopy with two different devices: a randomized study. Endoscopy 2007;39:1041-1045.","DOI":"10.1055\/s-2007-966943"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"CAVE DR, FLEISCHER DE, LEIGHTON JA, FAIGEL DO, HEIGH RI, SHARMA VH, et al. A multicenter randomized comparison of the Endocapsule and the Pillcam SB. Gastrointest Endosc 2008;68:487-494.","DOI":"10.1016\/j.gie.2007.12.037"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"KIM HM, KIM YJ, KIM HJ, PARK S, PARK JY, SHIN SK, et al. A pilot study of sequential capsule endoscopy using MiroCam and PillCam SB devices with different transmission technologies. Gut Liver 2010;4:192-200.","DOI":"10.5009\/gnl.2010.4.2.192"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"PIOCHE M, GAUDIN JL, FILOCHE B, JACOB P, LAMOULIATTE H, LAPALUS MG, et al. Prospective, randomized comparison of two small-bowel capsule endoscopy systems in patients with obscure GI bleeding. Gastrointest Endosc 2011;73:1181-1188.","DOI":"10.1016\/j.gie.2011.02.011"},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"CHOI EH, MERGENER K, SEMRAD C, FISHER L, CAVE DR, DODIG M, et al. A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope. Gastrointest Endosc 2013;78:325-332.","DOI":"10.1016\/j.gie.2013.02.039"},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"ZWINGER LL, SIEGMUND B, STROUX A, ADLER A, VELTZKE-SCHLIEKER W, WENTRUP R, et al. CapsoCam SV-1 versus PillCam SB 3 in the detection of obscure gastrointestinal bleeding: Results of a prospective randomized comparative multicenter study. J Clin Gastroenterol 2019;53:e101-106","DOI":"10.1097\/mcg.0000000000000994"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"BRANCHI F, FERRETTI F, ORLANDO S, TONTINI GE, PENAGINI R, VECCHI M, et al. Small-bowel capsule endoscopy in patients with celiac disease, axial versus lateral\/panoramic view: Results from a prospective randomized trial. Dig Endosc 2020;32:778-784.","DOI":"10.1111\/den.13575"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"DOLAK W, KULNIGG-DABSCH S, EVSTATIEV R, GASCHE C, TRAUNER M, P\u00dcSP\u00d6K A. A randomized head-to-head study of small-bowel imaging comparing MiroCam and EndoCapsule. Endoscopy 2012;44:1012-1020.","DOI":"10.1055\/s-0032-1310158"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"KOFFAS A, LASKARATOS FM, EPSTEIN O. Training in video capsule endoscopy: Current status and unmet needs. World J Gastrointest Endosc 2019;11:395-402.","DOI":"10.4253\/wjge.v11.i6.395"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"MOGLIA A, MENCIASSI A, DARIO P, CUSCHIERI A. Capsule endoscopy: progress update and challenges ahead. Nat Rev Gastroenterol Hepatol 2009; 6:353-362.","DOI":"10.1038\/nrgastro.2009.69"},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"MUSSETTO A, FUCCIO L, DARI S, GASPERONI S, CANTONI F, BRANCACCIO ML, et al. MiroCam capsule for obscure gastrointestinal bleeding: a prospective, single centre experience. Dig Liver Dis 2013;45:124-128.","DOI":"10.1016\/j.dld.2012.08.016"},{"key":"ref32","doi-asserted-by":"publisher","unstructured":"LIAO Z, GAO R, LI F, XU C, ZHOU Y, WANG JS, et al. Fields of applications, diagnostic yields and findings of OMOM capsule endoscopy in 2400 Chinese patients. World J Gastroenterol 2010;16:2669-2676.","DOI":"10.3748\/wjg.v16.i21.2669"}],"container-title":["Acta Gastro Enterologica Belgica"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T22:13:37Z","timestamp":1668118417000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ageb.be\/ageb-journal\/ageb-volume\/ageb-article\/2041\/Which%20model%20of%20small%20bowel%20capsule%20endoscopy%20has%20a%20better%20diagnostic%20yield\/?A%20systematic%20review%20and%20meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":33,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,9]]},"published-print":{"date-parts":[[2022,9]]}},"URL":"https:\/\/doi.org\/10.51821\/85.3.10322","relation":{},"ISSN":["1784-3227"],"issn-type":[{"value":"1784-3227","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}