{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:17:27Z","timestamp":1792790247677,"version":"4.5.0"},"reference-count":67,"publisher":"Korean Society of Animal Science and Technology","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Korea Atomic Energy Research Institute","award":["52332026"],"award-info":[{"award-number":["52332026"]}],"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Rural Development Administration","award":["PJ01564402"],"award-info":[{"award-number":["PJ01564402"]}],"id":[{"id":"https:\/\/ror.org\/03xs9yg50","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.ejast.org"],"crossmark-restriction":true},"short-container-title":["J Anim Sci Technol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>Dietary supplementation effects with Lactiplantibacillus\n                        argentoratensis strain AGMB00912 (LA) on gut microbiota and\n                    metabolic functions of weaned piglets were investigated. Eight 25-day-old weaned\n                    piglets were evenly divided into a control group and an LA-supplemented group,\n                    with the LA group receiving 1.0 \u00d7 108 CFU\/mL of LA daily for\n                    10 days. Fecal samples taken on the 10th day were analyzed using 16S\n                    rRNA gene sequencing to assess microbial composition and metabolic function\n                    prediction. Supplementation with LA promoted a stable microbial environment by\n                    increasing the relative abundance of short-chain fatty acid-producing bacteria,\n                    including Faecalitalea, Catenibacterium, and\n                        Butyrivibrio, while reducing harmful genera like\n                        Treponema and Campylobacter.\n                    Administration of LA significantly influenced the metabolic activity of the\n                    microbial community, particularly by upregulating carbohydrate metabolism\n                    pathways, which enhanced the capacity for short-chain fatty acid production.\n                    This shift in microbial metabolism also extended to pathways involved in the\n                    biosynthesis of amino acids, lipids, cofactors, and vitamins, indicating an\n                    improved capacity for microbial-driven nutrient assimilation and utilization.\n                    Furthermore, LA supplementation promoted the biosynthesis of antimicrobial\n                    non-ribosomal peptides within the microbiome, crucial for inhibiting the growth\n                    of pathogenic microorganisms and maintaining microbial balance. The modulation\n                    of microbial metabolism is also predicted to reduce glycan degradation and\n                    increase peptidoglycan biosynthesis, contributing to enhanced gut barrier\n                    function and a more regulated immune response. These metabolic changes within\n                    the microbial community are predicted to stabilize the gut microbiota, providing\n                    enhanced disease resistance and supporting the overall health and growth of\n                    weaned piglets.<\/jats:p>","DOI":"10.5187\/jast.2024.e122","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:07:54Z","timestamp":1736986074000},"page":"562-585","update-policy":"https:\/\/doi.org\/10.5187\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Modulation of microbial community and metabolism through\n                        Lactiplantibacillus argentoratensis AGMB00912\n                    supplementation in weaning piglets"],"prefix":"10.5187","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1941-1200","authenticated-orcid":false,"given":"Ki-Nam","family":"Yoon","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"},{"id":[{"id":"https:\/\/ror.org\/05kzjxq56","id-type":"ROR","asserted-by":"publisher"}],"name":"Research Institute of Agricultural Science and Technology, Chonnam National University, Gwangju 61186, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3531-1971","authenticated-orcid":false,"given":"Han Gyu","family":"Lee","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xs9yg50","id-type":"ROR","asserted-by":"publisher"}],"name":"Animal Diseases and Health Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9080-2436","authenticated-orcid":false,"given":"Seo-Joon","family":"Yeom","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5810-3245","authenticated-orcid":false,"given":"Sang-Su","family":"Kim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9525-8543","authenticated-orcid":false,"given":"Jong-Heum","family":"Park","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9531-6195","authenticated-orcid":false,"given":"Beom-Seok","family":"Song","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5545-2969","authenticated-orcid":false,"given":"Seung-Won","family":"Yi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xs9yg50","id-type":"ROR","asserted-by":"publisher"}],"name":"Animal Diseases and Health Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3129-2942","authenticated-orcid":false,"given":"Tai-Young","family":"Hur","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xs9yg50","id-type":"ROR","asserted-by":"publisher"}],"name":"Animal Diseases and Health Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2917-4923","authenticated-orcid":false,"given":"Jong-Bang","family":"Eun","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05kzjxq56","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Food Science and Technology, Graduate School of Chonnam National University, Gwangju 61186, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4613-4680","authenticated-orcid":false,"given":"Seung-Hwan","family":"Park","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03ep23f07","id-type":"ROR","asserted-by":"publisher"}],"name":"Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-7593","authenticated-orcid":false,"given":"Ju Huck","family":"Lee","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03ep23f07","id-type":"ROR","asserted-by":"publisher"}],"name":"Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1366-6090","authenticated-orcid":false,"given":"Hyeun Bum","family":"Kim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/058pdbn81","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal Biotechnology, Dankook University, Cheonan 31116, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0405-7621","authenticated-orcid":false,"given":"Ju-Hoon","family":"Lee","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04h9pn542","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Korea"},{"id":[{"id":"https:\/\/ror.org\/04h9pn542","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Food and Animal Biotechnology, Seoul National University, Seoul 08826, Korea"},{"id":[{"id":"https:\/\/ror.org\/04h9pn542","id-type":"ROR","asserted-by":"publisher"}],"name":"Center for Food and Bioconvergence, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3746-7347","authenticated-orcid":false,"given":"Jae-Kyung","family":"Kim","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01xb4fs50","id-type":"ROR","asserted-by":"publisher"}],"name":"Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3132","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"key2.0261002113731e+13_B1","doi-asserted-by":"crossref","first-page":"628258","DOI":"10.3389\/fvets.2021.628258","article-title":"Intestinal health of pigs upon weaning: challenges and\n                        nutritional intervention","volume":"8","author":"Zheng","year":"2021","journal-title":"Front Vet Sci."},{"key":"key2.0261002113731e+13_B2","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.tim.2017.05.004","article-title":"Gut microbiota dysbiosis in postweaning piglets: understanding\n                        the keys to health","volume":"25","author":"Gresse","year":"2017","journal-title":"Trends Microbiol."},{"key":"key2.0261002113731e+13_B3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.livsci.2010.06.037","article-title":"Microbial succession in the gastrointestinal tract (GIT) of the\n                        preweaned pig","volume":"133","author":"Petri","year":"2010","journal-title":"Livest Sci."},{"key":"key2.0261002113731e+13_B4","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1111\/1462-2920.13272","article-title":"Age, introduction of solid feed and weaning are more important\n                        determinants of gut bacterial succession in piglets than breed and nursing\n                        mother as revealed by a reciprocal cross-fostering model","volume":"18","author":"Bian","year":"2016","journal-title":"Environ Microbiol."},{"key":"key2.0261002113731e+13_B5","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/lam.12559","article-title":"Effect of dietary protein sources on the small intestine\n                        microbiome of weaned piglets based on high\u2010throughput\n                        sequencing","volume":"62","author":"Cao","year":"2016","journal-title":"Lett Appl Microbiol."},{"key":"key2.0261002113731e+13_B6","doi-asserted-by":"crossref","first-page":"1600186","DOI":"10.1002\/mnfr.201600186","article-title":"Effects of pectin on fermentation characteristics, carbohydrate\n                        utilization, and microbial community composition in the gastrointestinal\n                        tract of weaning pigs","volume":"61","author":"Tian","year":"2017","journal-title":"Mol Nutr Food Res."},{"key":"key2.0261002113731e+13_B7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0100040","article-title":"Early-life environmental variation affects intestinal microbiota\n                        and immune development in new-born piglets","volume":"9","author":"Schokker","year":"2014","journal-title":"PLOS ONE."},{"key":"key2.0261002113731e+13_B8","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2527\/af.2016-0031","article-title":"The role of gut microbiota in the health and disease of\n                        pigs","volume":"6","author":"Fouhse","year":"2016","journal-title":"Anim Front."},{"key":"key2.0261002113731e+13_B9","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00430-13","article-title":"Streptomycin-induced inflammation enhances Escherichia coli gut\n                        colonization through nitrate respiration","volume":"4","author":"Spees","year":"2013","journal-title":"mBio."},{"key":"key2.0261002113731e+13_B10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nature18849","article-title":"Interactions between the microbiota and pathogenic bacteria in\n                        the gut","volume":"535","author":"B\u00e4umler","year":"2016","journal-title":"Nature."},{"key":"key2.0261002113731e+13_B11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/mi.2016.75","article-title":"Mechanisms of inflammation-driven bacterial dysbiosis in the\n                        gut","volume":"10","author":"Zeng","year":"2017","journal-title":"Mucosal Immunol."},{"key":"key2.0261002113731e+13_B12","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/B978-0-12-822909-5.00017-4","article-title":"Secondary metabolites from probiotic metabolism","author":"Ch\u00e1varri","year":"2021","journal-title":"Advances in probiotics: microorganisms in food and health."},{"key":"key2.0261002113731e+13_B13","doi-asserted-by":"crossref","first-page":"12846","DOI":"10.3390\/ijms222312846","article-title":"Gut-microbial metabolites, probiotics and their roles in type 2\n                        diabetes","volume":"22","author":"Zhai","year":"2021","journal-title":"Int J Mol Sci."},{"key":"key2.0261002113731e+13_B14","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1099\/ijsem.0.004107","article-title":"A taxonomic note on the genus Lactobacillus: description of 23\n                        novel genera, emended description of the genus Lactobacillus Beijerinck\n                        1901, and union of Lactobacillaceae and Leuconostocaceae","volume":"70","author":"Zheng","year":"2020","journal-title":"Int J Syst Evol Microbiol."},{"key":"key2.0261002113731e+13_B15","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/j.1365-2672.2006.02955.x","article-title":"Examination of Lactobacillus plantarum lactate metabolism side\n                        effects in relation to the modulation of aeration parameters","volume":"101","author":"Quatravaux","year":"2006","journal-title":"J Appl Microbiol."},{"key":"key2.0261002113731e+13_B16","doi-asserted-by":"crossref","first-page":"1440134","DOI":"10.3389\/fmicb.2024.1440134","article-title":"Lactiplantibacillus argentoratensis AGMB00912 protects weaning\n                        mice from ETEC infection and enhances gut health","volume":"15","author":"Yoon","year":"2024","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B17","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks808","article-title":"Evaluation of general 16S ribosomal RNA gene PCR primers for\n                        classical and next-generation sequencing-based diversity\n                        studies","volume":"41","author":"Klindworth","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"key2.0261002113731e+13_B18","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome\n                        data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat Biotechnol."},{"key":"key2.0261002113731e+13_B19","doi-asserted-by":"crossref","first-page":"109431","DOI":"10.1016\/j.vetmic.2022.109431","article-title":"Beneficial effects of probiotics on the pig production cycle: an\n                        overview of clinical impacts and performance","volume":"269","author":"Pereira","year":"2022","journal-title":"Vet Microbiol."},{"key":"key2.0261002113731e+13_B20","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00682-21","article-title":"Weaning age and its effect on the development of the swine gut\n                        microbiome and resistome","volume":"6","author":"Holman","year":"2021","journal-title":"mSystems."},{"key":"key2.0261002113731e+13_B21","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.3389\/fmicb.2016.01727","article-title":"Gradual changes of gut microbiota in weaned miniature\n                        piglets","volume":"7","author":"Hu","year":"2016","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B22","doi-asserted-by":"crossref","DOI":"10.1128\/aem.01296-22","article-title":"Bifidobacterium animalis promotes the growth of weaning piglets\n                        by improving intestinal development, enhancing antioxidant capacity, and\n                        modulating gut microbiota","volume":"88","author":"Pang","year":"2022","journal-title":"Appl Environ Microbiol."},{"key":"key2.0261002113731e+13_B23","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.3389\/fmicb.2017.01688","article-title":"The maturing development of gut microbiota in commercial piglets\n                        during the weaning transition","volume":"8","author":"Chen","year":"2017","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s13568-019-0755-z","article-title":"Effects of dietary supplementation of probiotic Enterococcus\n                        faecium on growth performance and gut microbiota in weaned\n                        piglets","volume":"9","author":"Hu","year":"2019","journal-title":"AMB Express."},{"key":"key2.0261002113731e+13_B25","doi-asserted-by":"crossref","first-page":"584","DOI":"10.3390\/microorganisms9030584","article-title":"Implications of tributyrin on gut microbiota shifts related to\n                        performances of weaning piglets","volume":"9","author":"Miragoli","year":"2021","journal-title":"Microorganisms."},{"key":"key2.0261002113731e+13_B26","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1017\/S1751731119002428","article-title":"Faecal microbiome sequences in relation to the egg-laying\n                        performance of hens using amplicon-based metagenomic association\n                        analysis","volume":"14","author":"Elokil","year":"2020","journal-title":"Animal."},{"key":"key2.0261002113731e+13_B27","doi-asserted-by":"crossref","first-page":"1101869","DOI":"10.3389\/fvets.2022.1101869","article-title":"Gut microbial shifts by synbiotic combination of Pediococcus\n                        acidilactici and lactulose in weaned piglets challenged with Shiga\n                        toxin-producing Escherichia coli","volume":"9","author":"Guevarra","year":"2022","journal-title":"Front Vet Sci."},{"key":"key2.0261002113731e+13_B28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.rvsc.2020.12.022","article-title":"Development of piglet gut microbiota at the time of weaning\n                        influences development of postweaning diarrhea: a field\n                        study","volume":"135","author":"Karasova","year":"2021","journal-title":"Res Vet Sci."},{"key":"key2.0261002113731e+13_B29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/jpn.12666","article-title":"Review on the effects of potential prebiotics on controlling\n                        intestinal enteropathogens Salmonella and Escherichia coli in pig\n                        production","volume":"102","author":"Tran","year":"2018","journal-title":"J Anim Physiol Anim Nutr."},{"key":"key2.0261002113731e+13_B30","doi-asserted-by":"crossref","first-page":"4537","DOI":"10.1128\/JCM.01537-06","article-title":"Identification of a novel, invasive, not-yet-cultivated Treponema\n                        sp. in the large intestine of pigs by PCR amplification of the 16S rRNA\n                        gene","volume":"44","author":"M\u00f8lbak","year":"2006","journal-title":"J Clin Microbiol."},{"key":"key2.0261002113731e+13_B31","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1128\/iai.61.8.3466-3475.1993","article-title":"Newborn piglet model for campylobacteriosis","volume":"61","author":"Babakhani","year":"1993","journal-title":"Infect Immun."},{"key":"key2.0261002113731e+13_B32","doi-asserted-by":"crossref","first-page":"10081","DOI":"10.1007\/s00253-016-7845-5","article-title":"Changes in the diversity and composition of gut microbiota of\n                        weaned piglets after oral administration of Lactobacillus or an\n                        antibiotic","volume":"100","author":"Zhang","year":"2016","journal-title":"Appl Microbiol Biotechnol."},{"key":"key2.0261002113731e+13_B33","doi-asserted-by":"crossref","first-page":"6389","DOI":"10.1038\/s41467-020-19929-w","article-title":"A collection of bacterial isolates from the pig intestine reveals\n                        functional and taxonomic diversity","volume":"11","author":"Wylensek","year":"2020","journal-title":"Nat Commun."},{"key":"key2.0261002113731e+13_B34","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1574-6968.2009.01749.x","article-title":"Biosynthesis and transcriptional analysis of thurincin H, a\n                        tandem repeated bacteriocin genetic locus, produced by Bacillus\n                        thuringiensis SF361","volume":"299","author":"Lee","year":"2009","journal-title":"FEMS Microbiol Lett."},{"key":"key2.0261002113731e+13_B35","first-page":"72","article-title":"A novel species of lactic acid bacteria, Ligilactobacillus pabuli\n                        sp. nov., isolated from alfalfa silage","author":"Tohno","year":"2022","journal-title":"Int J Syst Evol Microbiol."},{"key":"key2.0261002113731e+13_B36","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1186\/s12866-023-02993-9","article-title":"Genomic and metabonomic methods reveal the probiotic functions of\n                        swine-derived Ligilactobacillus salivarius","volume":"23","author":"Yang","year":"2023","journal-title":"BMC Microbiol."},{"key":"key2.0261002113731e+13_B37","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41588-019-0350-x","article-title":"Causal relationships among the gut microbiome, short-chain fatty\n                        acids and metabolic diseases","volume":"51","author":"Sanna","year":"2019","journal-title":"Nat Genet."},{"key":"key2.0261002113731e+13_B38","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1099\/00207713-50-4-1595","article-title":"Catenibacterium mitsuokai gen. nov., sp. nov., a Gram-positive\n                        anaerobic bacterium isolated from human faeces","volume":"50","author":"Kageyama","year":"2000","journal-title":"Int J Syst Evol Microbiol."},{"key":"key2.0261002113731e+13_B39","doi-asserted-by":"crossref","first-page":"1284603","DOI":"10.3389\/fmicb.2023.1284603","article-title":"The role of gut archaea in the pig gut microbiome: a\n                        mini-review","volume":"14","author":"Yang","year":"2023","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B40","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.3389\/fmicb.2017.02345","article-title":"Bifidobacteria and their molecular communication with the immune\n                        system","volume":"8","author":"Ruiz","year":"2017","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B41","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3390\/biomedicines9020183","article-title":"Monoassociation of preterm germ-free piglets with Bifidobacterium\n                        animalis subsp. lactis BB-12 and its impact on infection with Salmonella\n                        typhimurium","volume":"9","author":"Splichalova","year":"2021","journal-title":"Biomedicines."},{"key":"key2.0261002113731e+13_B42","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s40793-017-0285-8","article-title":"The complete genome sequence of the rumen bacterium Butyrivibrio\n                        hungatei MB2003","volume":"12","author":"Palevich","year":"2017","journal-title":"Stand Genomic Sci."},{"key":"key2.0261002113731e+13_B43","article-title":"Complete genome sequence of Collinsella aerofaciens isolated from\n                        the gut of a healthy Indian subject","volume":"5","author":"Bag","year":"2017","journal-title":"Genome Announc."},{"key":"key2.0261002113731e+13_B44","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3390\/microorganisms7030078","article-title":"Characterization of a novel butyric acid-producing bacterium\n                        Collinsella aerofaciens subsp. Shenzhenensis subsp. nov.","volume":"7","author":"Qin","year":"2019","journal-title":"Microorganisms."},{"key":"key2.0261002113731e+13_B45","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1099\/ijsem.0.000934","article-title":"Abyssivirga alkaniphila gen. nov., sp. nov., an alkane-degrading,\n                        anaerobic bacterium from a deep-sea hydrothermal vent system, and emended\n                        descriptions of Natranaerovirga pectinivora and Natranaerovirga\n                        hydrolytica","volume":"66","author":"Schouw","year":"2016","journal-title":"Int J Syst Evol Microbiol."},{"key":"key2.0261002113731e+13_B46","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41587-020-0548-6","article-title":"PICRUSt2 for prediction of metagenome functions","volume":"38","author":"Douglas","year":"2020","journal-title":"Nat Biotechnol."},{"key":"key2.0261002113731e+13_B47","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s40168-020-00815-y","article-title":"Inference-based accuracy of metagenome prediction tools varies\n                        across sample types and functional categories","volume":"8","author":"Sun","year":"2020","journal-title":"Microbiome."},{"key":"key2.0261002113731e+13_B48","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1038\/sj.onc.1208615","article-title":"The p53 pathway: positive and negative feedback\n                        loops","volume":"24","author":"Harris","year":"2005","journal-title":"Oncogene."},{"key":"key2.0261002113731e+13_B49","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1136\/gut.2006.093484","article-title":"PPAR\u03b3 as a new therapeutic target in inflammatory bowel\n                        diseases","volume":"55","author":"Dubuquoy","year":"2006","journal-title":"Gut."},{"key":"key2.0261002113731e+13_B50","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1515\/hsz-2022-0321","article-title":"Membrane damage and repair: a thin line between life and\n                        death","volume":"404","author":"Barisch","year":"2023","journal-title":"Biol Chem."},{"key":"key2.0261002113731e+13_B51","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.devcel.2020.03.023","article-title":"The peroxisome: a new player in intestinal epithelial\n                        repair","volume":"53","author":"Bellec","year":"2020","journal-title":"Dev Cell."},{"key":"key2.0261002113731e+13_B52","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1152\/physrev.00009.2014","article-title":"NOD-like receptors: versatile cytosolic sentinels","volume":"95","author":"Motta","year":"2015","journal-title":"Physiol Rev."},{"key":"key2.0261002113731e+13_B53","doi-asserted-by":"crossref","first-page":"7851","DOI":"10.3168\/jds.2020-18187","article-title":"Lactobacillus gasseri JM1 with potential probiotic\n                        characteristics alleviates inflammatory response by activating the PI3K\/Akt\n                        signaling pathway in vitro","volume":"103","author":"Sun","year":"2020","journal-title":"J Dairy Sci."},{"key":"key2.0261002113731e+13_B54","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12934-014-0094-3","article-title":"Insights into glycogen metabolism in Lactobacillus acidophilus:\n                        impact on carbohydrate metabolism, stress tolerance and gut\n                        retention","volume":"13","author":"Goh","year":"2014","journal-title":"Microb Cell Fact."},{"key":"key2.0261002113731e+13_B55","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3390\/ijms23031105","article-title":"Gut microbiota and short chain fatty acids: implications in\n                        glucose homeostasis","volume":"23","author":"Portincasa","year":"2022","journal-title":"Int J Mol Sci."},{"key":"key2.0261002113731e+13_B56","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.3390\/nu7042930","article-title":"The role of microbial amino acid metabolism in host\n                        metabolism","volume":"7","author":"Neis","year":"2015","journal-title":"Nutrients."},{"key":"key2.0261002113731e+13_B57","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1017\/S0007114518002891","article-title":"Involvement of calcium-sensing receptor activation in the\n                        alleviation of intestinal inflammation in a piglet model by dietary aromatic\n                        amino acid supplementation","volume":"120","author":"Liu","year":"2018","journal-title":"Br J Nutr."},{"key":"key2.0261002113731e+13_B58","doi-asserted-by":"crossref","first-page":"554","DOI":"10.3389\/fphar.2020.00554","article-title":"Like cures like: pharmacological activity of anti-inflammatory\n                        lipopolysaccharides from gut microbiome","volume":"11","author":"Lin","year":"2020","journal-title":"Front Pharmacol."},{"key":"key2.0261002113731e+13_B59","doi-asserted-by":"crossref","first-page":"5562","DOI":"10.3390\/ijms23105562","article-title":"Involvement of gut microbial metabolites derived from diet on\n                        host energy homeostasis","volume":"23","author":"Nishida","year":"2022","journal-title":"Int J Mol Sci."},{"key":"key2.0261002113731e+13_B60","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1042\/BST20140176","article-title":"Coenzyme A and its derivatives: renaissance of a textbook\n                        classic","volume":"42","author":"Theodoulou","year":"2014","journal-title":"Biochem Soc Trans."},{"key":"key2.0261002113731e+13_B61","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3390\/cells7070084","article-title":"Vitamin B\u2086 and its role in cell metabolism and\n                        physiology","volume":"7","author":"Parra","year":"2018","journal-title":"Cells."},{"key":"key2.0261002113731e+13_B62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2018.1455790","article-title":"Gut microbiota as a source of novel\n                        antimicrobials","volume":"10","author":"Garcia-Gutierrez","year":"2019","journal-title":"Gut Microbes."},{"key":"key2.0261002113731e+13_B63","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.bbamem.2007.06.007","article-title":"Murein (peptidoglycan) structure, architecture and biosynthesis\n                        in Escherichia coli","volume":"1778","author":"Vollmer","year":"2008","journal-title":"Biochim Biophys Acta."},{"key":"key2.0261002113731e+13_B64","doi-asserted-by":"crossref","first-page":"500","DOI":"10.3389\/fmicb.2019.00500","article-title":"Peptidoglycan muropeptides: release, perception, and functions as\n                        signaling molecules","volume":"10","author":"Irazoki","year":"2019","journal-title":"Front Microbiol."},{"key":"key2.0261002113731e+13_B65","doi-asserted-by":"crossref","first-page":"15789","DOI":"10.1038\/s41598-017-16190-y","article-title":"Porphyromonas gingivalis lipopolysaccharides act exclusively\n                        through TLR4 with a resilience between mouse and human","volume":"7","author":"Nativel","year":"2017","journal-title":"Sci Rep."},{"key":"key2.0261002113731e+13_B66","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.3390\/nu14071497","article-title":"Sodium benzoate\u2014harmfulness and potential use in therapies\n                        for disorders related to the nervous system: a review","volume":"14","author":"Walczak-Nowicka","year":"2022","journal-title":"Nutrients."},{"key":"key2.0261002113731e+13_B67","doi-asserted-by":"crossref","first-page":"113623","DOI":"10.1016\/j.ecoenv.2022.113623","article-title":"Effects of bisphenol A on reproductive toxicity and gut\n                        microbiota dysbiosis in male rats","volume":"239","author":"Liu","year":"2022","journal-title":"Ecotoxicol Environ Saf."}],"container-title":["Journal of Animal Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.ejast.org\/download\/download_pdf?doi=10.5187\/jast.2024.e122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.ejast.org\/download\/download_pdf?doi=10.5187\/jast.2024.e122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:49:39Z","timestamp":1790909379000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.ejast.org\/archive\/view_article?doi=10.5187\/jast.2024.e122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":67,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,3,31]]},"published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.5187\/jast.2024.e122"],"URL":"https:\/\/doi.org\/10.5187\/jast.2024.e122","relation":{},"ISSN":["2672-0191","2055-0391"],"issn-type":[{"value":"2672-0191","type":"print"},{"value":"2055-0391","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2024-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}