{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:16:25Z","timestamp":1792790185576,"version":"4.5.0"},"reference-count":33,"publisher":"Korean Society of Animal Science and Technology","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Agricultural Research Development Agency","award":["HRD65050085"],"award-info":[{"award-number":["HRD65050085"]}],"id":[{"id":"https:\/\/ror.org\/01shbv660","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.ejast.org"],"crossmark-restriction":true},"short-container-title":["J Anim Sci Technol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>Antral follicle count (AFC) is considered a useful non-invasive method for\n                    providing valuable insights into a female\u2019s ovarian reserve. However, the\n                    influence of AFC and corpora lutea (CL) at the time of exogenous hormonal\n                    trigger (synchronization) on ovarian response to stimulation and fertility in\n                    goats remains unclear. This research aims to explore the impacts of different\n                    AFC and CL presence at the onset of hormonal synchronization (on Day 0) for\n                    fixed-time artificial insemination (fixed-time AI) on response to hormonal\n                    stimulation and fertility in Boer does. On Day 0, a transrectal ultrasound was\n                    performed to detect all visible antral follicle (AF; \u2265 2 mm) and CL.\n                    Based on AFC and CL, 128 does were divided into four groups in a 2 \u00d7 2\n                    factorial trial (AFC I [\u2264 3 follicles], AFC II [&gt; 3 follicles], with\n                    CL [CL+], and without CL [CL\u2013]): groups I (AFC I \u00d7 CL+), II (AFC I\n                    \u00d7 CL\u2013), III (AFC II \u00d7 CL+), and IV (AFC II \u00d7\n                    CL\u2013). On Day 7, does were inseminated with cervical AI using the first\n                    dose of frozen thawed semen. On Day 7, there was no interaction between AFC and\n                    CL on all parameters of ovarian follicles. The follicle and reproductive\n                    parameters and ovarian responsive rate did not differ between CL+ and CL\u2013\n                    does. Does with AFC &gt; 3 follicles had a greater number of large AF (&gt; 4\n                    mm) and ovarian increased the responsive rate than does having AFC \u2264 3\n                    follicles on their ovaries. The multiple kidding (twin kidding and triplet\n                    kidding) rate and fertility were superior for does having AFC &gt; 3 follicles\n                    than does having AFC \u2264 3 follicles at the beginning of hormonal\n                    synchronization for fixed-time AI. Moreover, the likelihood of ovarian response\n                    to synchronization and multiple kidding increased by 3.03 and 4.09 times,\n                    respectively, in does with a greater total number of AF (AFC &gt; 3 follicles)\n                    at the time of exogenous hormonal synchronization. Higher ovarian responses to\n                    stimulation and fertility are demonstrated by the previous appearance of more\n                    AFC available for selection into the ovulatory pool in poly-ovulatory does when\n                    performing hormonal synchronization for fixed-time AI.<\/jats:p>","DOI":"10.5187\/jast.2024.e16","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T23:17:54Z","timestamp":1708384674000},"page":"420-434","update-policy":"https:\/\/doi.org\/10.5187\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exploring the impacts of different antral follicle count and luteal\n                    presence on ovarian response and fertility in inseminated Boer\n                    does"],"prefix":"10.5187","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9490-1357","authenticated-orcid":false,"given":"Tossapol","family":"Moonmanee","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"},{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Functional Feed Innovation Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6128-7198","authenticated-orcid":false,"given":"Nalinthip","family":"Promsao","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7517-7834","authenticated-orcid":false,"given":"Punnawut","family":"Yama","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8275-9222","authenticated-orcid":false,"given":"Assawadet","family":"Suriard","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9156-0270","authenticated-orcid":false,"given":"Wichayaporn","family":"Butmata","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5310-6458","authenticated-orcid":false,"given":"Siriluck","family":"Ampawa","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7429-0993","authenticated-orcid":false,"given":"Raktham","family":"Mektrirat","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05m2fqn25","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Veterinary Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1635-7624","authenticated-orcid":false,"given":"Julakorn","family":"Panatuk","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03c7s1f64","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Animal Science and Technology, Maejo University, Chiang Mai 50290, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0314-0813","authenticated-orcid":false,"given":"Payungsuk","family":"Intawicha","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00a5mh069","id-type":"ROR","asserted-by":"publisher"}],"name":"Division of Animal Science, School of Agriculture and Natural Resources, University of Phayao, Phayao 56000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4565-4978","authenticated-orcid":false,"given":"Jiratti","family":"Thammasiri","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02g702008","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Animal Production Technology, Faculty of Agricultural Technology, Kalasin University, Kalasin 46000, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9162-6820","authenticated-orcid":false,"given":"Chien-Kai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Animal Science, National Chung Hsing University, Taichung 40227, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3132","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"key2.026100211371e+13_B1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40781-016-0093-5","article-title":"Effects of culture media conditions on production of eggs\n                        fertilized in vitro of embryos derived from ovary of high grade\n                        Hanwoo","volume":"58","author":"Lee","year":"2016","journal-title":"J Anim Sci Technol."},{"key":"key2.026100211371e+13_B2","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.5713\/ajas.19.0162","article-title":"The use of pituitary adenylate cyclase-activating polypeptide in\n                        the pre-maturation system improves in vitro developmental competence from\n                        small follicles of porcine oocytes","volume":"32","author":"Park","year":"2019","journal-title":"Asian-Australas J Anim Sci."},{"key":"key2.026100211371e+13_B3","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2220\/biomedres.37.63","article-title":"The relationship between antral follicle count in a bovine ovary\n                        and developmental competence of in vitro-grown oocytes derived from early\n                        antral follicles","volume":"37","author":"Nagai","year":"2016","journal-title":"Biomed Res."},{"key":"key2.026100211371e+13_B4","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3168\/jdsc.2022-0283","article-title":"Associations of antral follicle count with fertility in cattle: a\n                        review","volume":"4","author":"Alward","year":"2023","journal-title":"JDS Commun."},{"key":"key2.026100211371e+13_B5","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.theriogenology.2015.09.026","article-title":"Association between antral follicle count and reproductive\n                        measures in New Zealand lactating dairy cows maintained in a pasture-based\n                        production system","volume":"85","author":"Martinez","year":"2016","journal-title":"Theriogenology."},{"key":"key2.026100211371e+13_B6","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3390\/biology11040523","article-title":"Understanding the ovarian interrelationship with low antral\n                        follicle counts (AFC) in the in vivo Bos indicus cow model: unilateral and\n                        bilateral main AFC as possible biomarkers of ovarian response to hormonal\n                        synchronisation","volume":"11","author":"U-Krit","year":"2022","journal-title":"Biology."},{"key":"key2.026100211371e+13_B7","doi-asserted-by":"crossref","first-page":"85","DOI":"10.15406\/jdvar.2020.09.00284","article-title":"Prolificacy in small ruminants","volume":"9","author":"Plakkot","year":"2020","journal-title":"J Dairy Vet Anim Res."},{"key":"key2.026100211371e+13_B8","doi-asserted-by":"crossref","first-page":"628","DOI":"10.5713\/ajas.2013.13658","article-title":"Prolificacy and its relationship with age, body weight, parity,\n                        previous litter size and body linear type traits in meat-type\n                        goats","volume":"27","author":"Haldar","year":"2014","journal-title":"Asian-Australas J Anim Sci."},{"key":"key2.026100211371e+13_B9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.theriogenology.2017.05.026","article-title":"Ovulation rate, antral follicle count, and circulating\n                        anti-M\u00fcllerian hormone in Trio allele carriers, a novel high\n                        fecundity bovine genotype","volume":"101","author":"Garc\u00eda-Guerra","year":"2017","journal-title":"Theriogenology."},{"key":"key2.026100211371e+13_B10","doi-asserted-by":"crossref","first-page":"660","DOI":"10.21451\/1984-3143-AR2018-0027","article-title":"Mechanisms regulating follicle selection in ruminants: lessons\n                        learned from multiple ovulation models","volume":"15","author":"Garcia-Guerra","year":"2018","journal-title":"Anim Reprod."},{"key":"key2.026100211371e+13_B11","first-page":"449","article-title":"Effect of short-term and long-term synthetic progesterone on\n                        estrous synchronization and conception rate in Thai-native\n                        goat","volume":"11","author":"Khanthusaeng","year":"2012","journal-title":"Chiang Mai Univ J Nat Sci."},{"key":"key2.026100211371e+13_B12","first-page":"669","article-title":"Ovulation rate, metabolite and hormonal profiles of ewes in low\n                        body condition stimulated with high-energy diet during the late-luteal phase\n                        of the estrous cycle","volume":"28","author":"Moonmanee","year":"2018","journal-title":"J Anim Plant Sci."},{"key":"key2.026100211371e+13_B13","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1262\/jrd.09-179T","article-title":"Ovarian follicular dynamics and hormonal changes in goats during\n                        early pregnancy","volume":"56","author":"Kandiel","year":"2010","journal-title":"J Reprod Dev."},{"key":"key2.026100211371e+13_B14","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/rda.12690","article-title":"Pre-selection test to identify high responder donor\n                        goats","volume":"51","author":"Balaro","year":"2016","journal-title":"Reprod Domest Anim."},{"key":"key2.026100211371e+13_B15","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.anireprosci.2011.02.015","article-title":"Ovarian follicular response to different hormonal stimulation\n                        treatments in Canind\u00e9 goats","volume":"125","author":"de Sousa","year":"2011","journal-title":"Anim Reprod Sci."},{"key":"key2.026100211371e+13_B16","doi-asserted-by":"crossref","first-page":"13","DOI":"10.24425\/pjvs.2022.140835","article-title":"Reproductive performance with short-time controlled internal drug\n                        release (CIDR)-based synchronization protocol for fixed-time artificial\n                        insemination in nulliparous and primiparous Saanen goats","volume":"25","author":"Ozis Altincekic","year":"2022","journal-title":"Pol J Vet Sci."},{"key":"key2.026100211371e+13_B17","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1071\/RD21086","article-title":"The ovarian follicle of ruminants: the path from conceptus to\n                        adult","volume":"33","author":"Juengel","year":"2021","journal-title":"Reprod Fertil Dev."},{"key":"key2.026100211371e+13_B18","doi-asserted-by":"crossref","first-page":"100744","DOI":"10.1016\/j.animal.2023.100744","article-title":"Review: The ovarian follicular reserve \u2013 implications for\n                        fertility in ruminants","volume":"17","author":"Mossa","year":"2023","journal-title":"Animal."},{"key":"key2.026100211371e+13_B19","doi-asserted-by":"crossref","first-page":"106803","DOI":"10.1016\/j.smallrumres.2022.106803","article-title":"Ovarian assessment for pre-selection of embryo donor\n                        ewes","volume":"216","author":"Brasil","year":"2022","journal-title":"Small Rumin Res."},{"key":"key2.026100211371e+13_B20","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.anireprosci.2006.10.016","article-title":"Association between numbers of ovarian follicles in the first\n                        follicle wave and superovulatory response in ewes","volume":"100","author":"Mossa","year":"2007","journal-title":"Anim Reprod Sci."},{"key":"key2.026100211371e+13_B21","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.3923\/javaa.2012.3385.3389","article-title":"Evaluation of protocols based on synthetic progesterone and\n                        gonadotropin on estrus and ovulatory response in Thai-native\n                        goats","volume":"11","author":"Lertchunhakiat","year":"2012","journal-title":"J Anim Vet Adv."},{"key":"key2.026100211371e+13_B22","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S2305-0500(15)30014-2","article-title":"Recent advances on synchronization of ovulation in goats, out of\n                        season, for a more sustainable production","volume":"4","author":"Sim\u00f5es","year":"2015","journal-title":"Asian Pac J Reprod."},{"key":"key2.026100211371e+13_B23","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0378-4320(03)00095-2","article-title":"The pattern and manipulation of ovarian follicular growth in\n                        goats","volume":"78","author":"Rubianes","year":"2003","journal-title":"Anim Reprod Sci."},{"key":"key2.026100211371e+13_B24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.smallrumres.2015.02.014","article-title":"Comparison of follicular dynamics and hormone profiles in Boer\n                        goats examined during the breeding and non-breeding seasons in the tropics\n                        of Queensland, Australia","volume":"125","author":"Nogueira","year":"2015","journal-title":"Small Rumin Res."},{"key":"key2.026100211371e+13_B25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.anireprosci.2016.06.003","article-title":"Effect of hormonal synchronisation and\/or short-term\n                        supplementation with maize on follicular dynamics and hormone profiles in\n                        goats during the non-breeding season","volume":"171","author":"Nogueira","year":"2016","journal-title":"Anim Reprod Sci."},{"key":"key2.026100211371e+13_B26","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1186\/s12864-020-6671-4","article-title":"Comprehensive analysis of mRNAs and miRNAs in the ovarian\n                        follicles of uniparous and multiple goats at estrus phase","volume":"21","author":"Zou","year":"2020","journal-title":"BMC Genomics."},{"key":"key2.026100211371e+13_B27","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.anireprosci.2012.01.008","article-title":"Genetic improvement of reproductive efficiency of sheep and\n                        goats","volume":"130","author":"Notter","year":"2012","journal-title":"Anim Reprod Sci."},{"key":"key2.026100211371e+13_B28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0303-7207(98)00174-9","article-title":"Follicle selection in sheep with breed differences in ovulation\n                        rate","volume":"145","author":"Baird","year":"1998","journal-title":"Mol Cell Endocrinol."},{"key":"key2.026100211371e+13_B29","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1071\/RD09161","article-title":"Regulation of folliculogenesis and the determination of ovulation\n                        rate in ruminants","volume":"23","author":"Scaramuzzi","year":"2011","journal-title":"Reprod Fertil Dev."},{"key":"key2.026100211371e+13_B30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.theriogenology.2016.04.017","article-title":"Driving folliculogenesis by the oocyte-somatic cell dialog:\n                        lessons from genetic models","volume":"86","author":"Monniaux","year":"2016","journal-title":"Theriogenology."},{"key":"key2.026100211371e+13_B31","doi-asserted-by":"crossref","DOI":"10.1111\/asj.13384","article-title":"Increased number of large non-atretic follicles and co-dominance\n                        effects account for high litter sizes in Bonga sheep","volume":"91","author":"Tera Dolebo","year":"2020","journal-title":"Anim Sci J."},{"key":"key2.026100211371e+13_B32","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/rda.12165","article-title":"Differential ovarian morphometry and follicular expression of\n                        BMP15, GDF9 and BMPR1B influence the prolificacy in goat","volume":"48","author":"Pramod","year":"2013","journal-title":"Reprod Domest Anim."},{"key":"key2.026100211371e+13_B33","doi-asserted-by":"crossref","first-page":"5028","DOI":"10.3168\/jds.2016-12240","article-title":"Manipulation of reproductive seasonality using melatonin\n                        implantation in Anglo-Nubian does treated with controlled internal drug\n                        release and equine chorionic gonadotropin during the nonbreeding\n                        season","volume":"100","author":"El-Mokadem","year":"2017","journal-title":"J Dairy Sci."}],"container-title":["Journal of Animal Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.ejast.org\/download\/download_pdf?doi=10.5187\/jast.2024.e16","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.ejast.org\/download\/download_pdf?doi=10.5187\/jast.2024.e16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:47:57Z","timestamp":1790909277000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.ejast.org\/archive\/view_article?doi=10.5187\/jast.2024.e16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,3,31]]},"published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.5187\/jast.2024.e16"],"URL":"https:\/\/doi.org\/10.5187\/jast.2024.e16","relation":{},"ISSN":["2672-0191","2055-0391"],"issn-type":[{"value":"2672-0191","type":"print"},{"value":"2055-0391","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2023-11-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}