{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T13:47:56Z","timestamp":1785505676510,"version":"3.56.0"},"reference-count":29,"publisher":"Michigan State University College of Osteopathic Medicine Statewide Campus System","issue":"2","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec id=\"introduction\"> <jats:title>INTRODUCTION<\/jats:title> <jats:p>Neoplasms of the appendix are quite rare and found in approximately 1% of appendectomy specimens. These neoplasms have been pathologically categorized into various subgroups depending on cell of origin, and surgical treatment varies according to histological subtype and disease stage.<\/jats:p> <\/jats:sec> <jats:sec id=\"purpose\"> <jats:title>PURPOSE<\/jats:title> <jats:p>The purpose of this case series review was to evaluate the clinicopathological presentation and survival outcome of a sample of patients with appendiceal tumors.<\/jats:p> <\/jats:sec> <jats:sec id=\"methods\"> <jats:title>METHODS<\/jats:title> <jats:p>Before data collection, this project design was approved by the authors\u2019 institutional review board. Pathology records at our institution were reviewed for cases of appendiceal tumors from January 2007 to December 2016. A total of 31 patients were identified over this 10-year period. Retrospective data collection included patient demographics, presenting symptoms, tumor size, histologic diagnosis, initial and secondary management, perioperative and postoperative outcome, and survival benefits.<\/jats:p> <\/jats:sec> <jats:sec id=\"results\"> <jats:title>RESULTS<\/jats:title> <jats:p>Thirty one patients with four different appendiceal tumor subtypes were included in the study: Mucinous Cystadenoma, Mucinous Adenocarcinoma, Goblet Cell, and Carcinoid. The sample was comprised of 17 women (54.8%) and 14 men (45.2%) with an overall mean age of 50.1 (SD = 22.3). Subgroups of 13 (42%) patients had Carcinoid tumor, 12 (39%) had Mucinous Cystadenoma, four (13%) had Goblet cell tumor, and two (6%) had Mucinous Adenocarcinoma. The stage at presentation and tumor size also varied by histologic subtype. The most common presenting symptom was abdominal pain (64.5%), followed by a radiological identified mass (12.9%). Overall, 27 (87.1%) patients survived, and four (12.9%) were deceased.<\/jats:p> <\/jats:sec> <jats:sec id=\"conclusions\"> <jats:title>CONCLUSIONS<\/jats:title> <jats:p>The findings from this case series review provides a retrospective analysis of appendiceal tumor characteristics, follow up, and survival. Based on these results, the prognosis and management of patients with these tumors should be based on the histologic subtype and the extent of their disease.<\/jats:p> <\/jats:sec>","DOI":"10.51894\/001c.13487","type":"journal-article","created":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T19:37:28Z","timestamp":1613417848000},"source":"Crossref","is-referenced-by-count":6,"title":["Clinicopathological and Perioperative Outcome of Appendiceal Tumors: Case Review of 31 Patients"],"prefix":"10.51894","volume":"5","author":[{"given":"Haroutioun","family":"Boyajian","sequence":"first","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Majeski","sequence":"additional","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Flores","sequence":"additional","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sturtz","sequence":"additional","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Pathology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Baidoun","sequence":"additional","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Dughayli","sequence":"additional","affiliation":[{"name":"Henry Ford Wyandotte Hospital","department":["Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"29343","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1136\/jclinpath-2012-200843","article-title":"Pathology and prognosis in psudomyxoma peritonei: A review of 274 cases","volume":"65","author":"N. 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