{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T17:59:32Z","timestamp":1732039172210},"reference-count":0,"publisher":"University Library System, University of Pittsburgh","issue":"1","license":[{"start":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T00:00:00Z","timestamp":1587945600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["cajgh"],"abstract":"<jats:p>Introduction: Information on microbiological and susceptibility profiles of clinical isolates in Mongolia is scarce, hampering infection control and clinical care.Methods: Species and resistance profiles of 6334 clinical gram negative isolates, collected at Mongolia\u2019s National Center for Maternal and Child Health between 2014 and 2017 were analyzed.Results: Annual proportion of multidrug-resistance among E. coli and Enterobacter isolates increased from 2.8% to 16.6% and 3.5% to 22.6% respectively; Klebsiella isolates exhibiting susceptibilities suggestive of extended spectrum beta-lactamase (ESBL) production from 73% to 94%. By 2017, 60.6% of Klebsiella isolates were multidrug-resistant, most originated from intensive care wards. \u00a0Enterobacteriaceae exhibiting susceptibility patterns suggestive of ESBL production and multidrug-resistant organisms were common and their incidence increased rapidly.Conclusion: These findings will serve to build strategies to strengthen microbiological surveillance, diagnostics and infection control; and to develop empiric therapy and stewardship recommendations for Mongolia\u2019s largest Children\u2019s and Maternity hospital.<\/jats:p>","DOI":"10.5195\/cajgh.2020.371","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T18:59:59Z","timestamp":1588013999000},"source":"Crossref","is-referenced-by-count":1,"title":["Rapid Emergence of Multidrug-Resistance among Gram Negative Isolates at a Tertiary Pediatric and Maternity Hospital in Ulaanbaatar, Mongolia"],"prefix":"10.5195","volume":"9","author":[{"given":"Susanna","family":"Felsenstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarantsetseg","family":"Bira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narangerel","family":"Altanmircheg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enkhtur","family":"Shonkuuz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariuntuya","family":"Ochirpurev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Warburton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3176","published-online":{"date-parts":[[2020,4,27]]},"container-title":["Central Asian Journal of Global Health"],"original-title":[],"link":[{"URL":"http:\/\/cajgh.pitt.edu\/ojs\/cajgh\/article\/download\/371\/292","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/cajgh.pitt.edu\/ojs\/cajgh\/article\/download\/371\/292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T14:43:41Z","timestamp":1620917021000},"score":1,"resource":{"primary":{"URL":"http:\/\/cajgh.pitt.edu\/ojs\/cajgh\/article\/view\/371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,3,31]]}},"URL":"https:\/\/doi.org\/10.5195\/cajgh.2020.371","relation":{},"ISSN":["2166-7403"],"issn-type":[{"value":"2166-7403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,27]]}}}