{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:33:48Z","timestamp":1770888828981,"version":"3.50.1"},"reference-count":21,"publisher":"Korean Continence Society","issue":"2","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["einj.org"],"crossmark-restriction":true},"short-container-title":["Int Neurourol J"],"published-print":{"date-parts":[[2021,6,30]]},"abstract":"<jats:p>Purpose: To assess baseline clinical and urodynamic profiles of a contemporary cohort of men undergoing radical prostatectomy (RP) as part of the ROSE (Robotic and Open Surgery for Prostate Cancer: A Prospective, Multi-centre, Comparative Study of Functional and Oncological Outcomes) study.Methods: Men with localized prostate cancer undergoing RP were prospectively recruited to undergo clinical assessment and urodynamic testing prior to surgery as part of a clinical trial. The International Prostate Symptoms Score (IPSS) was used to determine participants\u2019 degree of lower urinary tract symptoms (LUTS).Results: Eighty-five men with a median age of 64.5 years and a median prostate-specific antigen level of 6.3 ng\/mL were prospectively recruited. Of patients with complete baseline data, 36 (50.7%), 28 (39.4%), and 7 (9.9%) had mild (IPSS&lt;8), moderate (IPSS 8\u201319), and severe (IPSS&gt;20) LUTS, respectively. Obstruction was identified in 18 men (29.5%), and 9 (14.8%) showed detrusor underactivity. Of the 15 patients with detrusor overactivity, 12 (80%) reported overactive bladder (OAB). Of men with urodynamic obstruction, 5 (31.3%), 10 (62.5%), and 1 (6.3%) reported mild, moderate, and severe LUTS, respectively. Of men without OAB, 4 (11.8%, P=0.002) showed filling phase abnormalities, 13 (46.4%, P=0.611) had flow rates of &lt;15 mL\/sec, and 7 (30.4%, P=0.767) showed obstruction. Of men with mild or no LUTS, 5 (20%, P=0.072) showed obstruction and 4 (16%, P=0.524) showed poor contractility.Conclusion: LUTS and OAB were common in men with localized prostate cancer undergoing RP. Detrusor overactivity and urodynamic filling phase abnormalities were strongly correlated with OAB. IPSS did not show a strong correlation with bladder outflow obstruction or detrusor underactivity. Urodynamic filling abnormalities were found in 11.8% of men without OAB. Symptomatic and functional assessment may therefore have a role in the preoperative counselling of patients and possibly guide postoperative management of LUTS, especially if OAB is present.<\/jats:p>","DOI":"10.5213\/inj.2040238.119","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T07:48:50Z","timestamp":1611042530000},"page":"157-163","update-policy":"https:\/\/doi.org\/10.5213\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Lower Urinary Tract Functional Assessment of Men Undergoing Radical Prostatectomy: Correlation of Preoperative Clinical and Urodynamic Parameters"],"prefix":"10.5213","volume":"25","author":[{"given":"Nicholas Faure","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashan","family":"Canagasingham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1692-0832","authenticated-orcid":true,"given":"Danielle","family":"Van Diepen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4137-6229","authenticated-orcid":true,"given":"Athina","family":"Pirpiris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0993-2176","authenticated-orcid":true,"given":"Vincent","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9848-969X","authenticated-orcid":true,"given":"Scott","family":"Leslie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6438-8732","authenticated-orcid":true,"given":"Ruban","family":"Thanigasalam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3166","reference":[{"key":"ref1","first-page":"125","volume-title":"Prostate cancer screening in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of follow-up","author":"Andriole","year":"2012"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20017"},{"key":"ref3","first-page":"43","volume-title":"A 16-yr follow-up of the European Randomized study of Screening for Prostate Cancer","author":"Hugosson","year":"2019"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.0154"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2003.04231.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199904000-00037"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1520-6777(1999)18"},{"key":"ref8","first-page":"67","volume-title":"Prostatic enlargement, symptomatology and pressure\/flow evaluation: interrelations in patients with symptomatic BPH","author":"Poulsen","year":"1994"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1520-6777(1996)15"},{"key":"ref10","first-page":"1549","volume-title":"The American Urological Association symptom index for benign prostatic hyperplasia. 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