{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:31:06Z","timestamp":1790494266598,"version":"4.1.0"},"reference-count":66,"publisher":"Korean Association for the Study of Intestinal Diseases","issue":"1","license":[{"start":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T00:00:00Z","timestamp":1580342400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["irjournal.org"],"crossmark-restriction":true},"short-container-title":["Intest Res"],"published-print":{"date-parts":[[2020,1,30]]},"DOI":"10.5217\/ir.2019.09147","type":"journal-article","created":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T06:37:48Z","timestamp":1580366268000},"page":"34-44","update-policy":"https:\/\/doi.org\/10.5217\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Biosimilars: concept, current status, and future perspectives in inflammatory bowel diseases"],"prefix":"10.5217","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5366-5749","authenticated-orcid":true,"given":"Sang Hyoung","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0860-3642","authenticated-orcid":true,"given":"Jae Cheol","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1463-3840","authenticated-orcid":true,"given":"Milan","family":"Lukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9501-0604","authenticated-orcid":true,"given":"Martin","family":"Kolar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7199-6851","authenticated-orcid":true,"given":"Edward V.","family":"Loftus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3168","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-305607"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000441203.56196.46"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jju017"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2017.05.003"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.09.012"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2371-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1586\/14737167.2014.957682"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2016.14.1.15"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2015.1098601"},{"key":"ref11","volume-title":"Guidance for industry: quality considerations in demonstrating biosimilarity to a therapeutic protein product to a reference product"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1586\/1744666X.2015.1090310"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202941"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-017-0122-6"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2011.343"},{"key":"ref16","volume-title":"FDA approves Inflectra, a biosimilar to Remicade"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4161\/mabs.25864"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-203091"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-203090"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12997"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-014-3392-z"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1586\/17474124.2015.1091309"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1586\/17474124.2015.1091308"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx002.456"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx002.004"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw085"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050516"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32196-2"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30068-5"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(17)30572-3"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1159\/000453343"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw216"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw198"},{"key":"ref34","volume-title":"AGA makes six recommendations to FDA on interchangeable biosimilars"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv096"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000436951.80898.6d"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030815"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08512-4"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2017.1323330"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv220"},{"key":"ref41","first-page":"S46","volume-title":"DOP033","author":"Lovasz","year":"2016"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309290"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw087"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4661-4"},{"key":"ref45","first-page":"S413","volume-title":"P617. Immunogenicity after switching from reference infliximab to biosimilar in children with Crohn\u2019s disease","author":"Sieczkowska","year":"2016"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(17)30573-5"},{"key":"ref47","volume-title":"Delivering on the potential of biosimilar medicines: the role of functioning competitive markets"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.06.007"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw090"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.7326\/M16-1432"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2013.0149"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666170406112304"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00322"},{"key":"ref54","volume-title":"US doctors poised to prescribe biosimilars"},{"key":"ref55","first-page":"119","volume-title":"A budget impact model for biosimilar infliximab in Crohn\u2019s disease in Bulgaria, the Czech Republic, Hungary, Poland, Romania, and Slovakia","author":"Brodszky","year":"2016"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-015-0233-1"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2016.02.023"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1080\/14737167.2017.1322509"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1177\/2050640617708952"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175826"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw138"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2016.155"},{"key":"ref63","volume-title":"Biosimilar Product Information"},{"key":"ref64","volume-title":"Medicines_Search_Biosimilar"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15071"},{"key":"ref66","first-page":"1756284819891081","volume-title":"SB5 shows crossimmunogenicity to adalimumab but not infliximab: results in patients with inflammatory bowel disease or rheumatoid arthritis","author":"Goncalves","year":"2019"}],"container-title":["Intestinal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/irjournal.org\/upload\/pdf\/ir-2019-09147.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/irjournal.org\/journal\/view.php?doi=10.5217\/ir.2019.09147","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/irjournal.org\/upload\/pdf\/ir-2019-09147.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T20:11:38Z","timestamp":1580760698000},"score":1,"resource":{"primary":{"URL":"http:\/\/irjournal.org\/journal\/view.php?doi=10.5217\/ir.2019.09147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,30]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"URL":"https:\/\/doi.org\/10.5217\/ir.2019.09147","relation":{},"ISSN":["1598-9100","2288-1956"],"issn-type":[{"value":"1598-9100","type":"print"},{"value":"2288-1956","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,30]]},"assertion":[{"value":"2019-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-30","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}