{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:01:12Z","timestamp":1792144872092,"version":"4.4.0"},"reference-count":22,"publisher":"Korean Association for the Study of Intestinal Diseases","content-domain":{"domain":["irjournal.org"],"crossmark-restriction":true},"short-container-title":["Intest Res"],"DOI":"10.5217\/ir.2025.00325","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:26:01Z","timestamp":1779236761000},"update-policy":"https:\/\/doi.org\/10.5217\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Real-world use and perceptions of advanced combined therapies in treating inflammatory bowel disease"],"prefix":"10.5217","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3084-5579","authenticated-orcid":true,"given":"Hsin-Yun","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University Hospital Jinshan Branch, New Taipei City, Taiwan"},{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3186-3056","authenticated-orcid":true,"given":"Zhi-Che","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University Hospital Jinshan Branch, New Taipei City, Taiwan"},{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4143-6607","authenticated-orcid":true,"given":"Meng-Tzu","family":"Weng","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"},{"name":"Department of Medical Research, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9046-4975","authenticated-orcid":true,"given":"Agnes Hiu Yan","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5221-7349","authenticated-orcid":true,"given":"Joyce Wing Yan","family":"Mak","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5944-3488","authenticated-orcid":true,"given":"Rupert W","family":"Leong","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Concord Repatriation General Hospital, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6850-4454","authenticated-orcid":true,"given":"Siew-Chien","family":"Ng","sequence":"additional","affiliation":[{"name":"Microbiota I-Center (MagIC), Hong Kong, China"},{"name":"Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China"},{"name":"New Cornerstone Science Laboratory, The Chinese University of Hong Kong, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3067-8061","authenticated-orcid":true,"given":"Uma","family":"Mahadevan","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2634-9668","authenticated-orcid":true,"given":"Fernando","family":"Magro","sequence":"additional","affiliation":[{"name":"Unit of Pharmacology and Therapeutics, Department of Biomedicine, Faculty of Medicine, University of Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3742-0634","authenticated-orcid":true,"given":"Deng-Chyang","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5017-5840","authenticated-orcid":true,"given":"Shu-Chen","family":"Wei","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3168","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(02)08512-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.11.041"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1215734"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1602773"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20014"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/s2468-1253(22)00427-7"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2023.09.010"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/apt.70309"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-021-06737-1"},{"key":"ref10","first-page":"251","volume":"19","author":"Solitano","year":"2023","journal-title":"Advanced combination treatment with biologic agents and novel small molecule drugs for inflammatory bowel disease"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12170"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/25151355221084535"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(03)00141-7"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.03.011"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2016.14.3.240"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12994"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izad032"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2023.00050"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2024.00060"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.03.034"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izad064"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14020590"}],"container-title":["Intestinal Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/irjournal.org\/upload\/pdf\/ir-2025-00325.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:57:07Z","timestamp":1780617427000},"score":1,"resource":{"primary":{"URL":"http:\/\/irjournal.org\/journal\/view.php?doi=10.5217\/ir.2025.00325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,19]]},"references-count":22,"URL":"https:\/\/doi.org\/10.5217\/ir.2025.00325","relation":{},"ISSN":["1598-9100","2288-1956"],"issn-type":[{"value":"1598-9100","type":"print"},{"value":"2288-1956","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,19]]},"assertion":[{"value":"2025-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-19","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}}]}}