{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:14:34Z","timestamp":1747228474529,"version":"3.40.5"},"reference-count":0,"publisher":"Narra Sains Indonesia","issue":"3","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Narra J"],"abstract":"<jats:p>\n\nIt is crucial for doctors to decide whether a thyroid nodule is benign or malignant when a patient presents with one, as it will significantly impact how the patient is managed in the future. However, it is not as straightforward to determine between the two; even a physical examination, thyroid function test, ultrasonography, and biopsy have been well performed. It can be more stressful if a patient has an increased risk of malignancy, such as age (below 20- and above 60-year-old), solid nodule, rapid growth, hoarseness, lymphadenopathy, and microcalcifications on the ultrasonography. The aim of this case was to present the management of a giant thyroid nodule with malignancy presentation and a benign biopsy finding. A 41-year-old male complained of a palpable neck mass, hoarseness, and dysphagia. The thyroid function test was normal. Ultrasonography revealed suspicion of malignancy with category 4 of American College of Radiology-Thyroid Imaging Reporting and Data System (ACR-TIRADS). The biopsy revealed follicular neoplasm, and was classified as Bethesda IV. The patient underwent a total thyroidectomy due to the large tumor size and symptoms. Histopathological findings post-surgery revealed a follicular thyroid adenoma. This case highlights a complex diagnosis and management of follicular thyroid neoplasm due to their potential for both benign and malignant. Comprehensive pre- and post-operative care is essential to determine the nature of nodules. Post-operative follow-up care might improve the patient\u2019s outcome and prevent complications.\n\n<\/jats:p>","DOI":"10.52225\/narra.v3i3.224","type":"journal-article","created":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T23:41:44Z","timestamp":1698018104000},"page":"e224","source":"Crossref","is-referenced-by-count":0,"title":["Complexity of diagnosis and management of a giant thyroid nodule: A case report and a concise literature"],"prefix":"10.52225","volume":"3","author":[{"given":"Sarah","family":"Firdausa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0569-4617","authenticated-orcid":false,"given":"Hendra","family":"Zufry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agustia S.","family":"Ekadamayanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna W.","family":"Sucipto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4368-2077","authenticated-orcid":false,"given":"Henry W.","family":"Burhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Pratama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s MMB.","family":"Benalcazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"29794","published-online":{"date-parts":[[2023,12,29]]},"container-title":["Narra J"],"original-title":[],"link":[{"URL":"https:\/\/narraj.org\/main\/article\/download\/224\/176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/narraj.org\/main\/article\/download\/224\/176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T04:11:37Z","timestamp":1713240697000},"score":1,"resource":{"primary":{"URL":"https:\/\/narraj.org\/main\/article\/view\/224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,29]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,12,29]]}},"URL":"https:\/\/doi.org\/10.52225\/narra.v3i3.224","relation":{},"ISSN":["2807-2618"],"issn-type":[{"type":"electronic","value":"2807-2618"}],"subject":[],"published":{"date-parts":[[2023,12,29]]}}}