{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T14:29:07Z","timestamp":1769524147751,"version":"3.49.0"},"reference-count":33,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Gastroenterol Hepatol Nutr"],"published-print":{"date-parts":[[2023]]},"DOI":"10.5223\/pghn.2023.26.4.201","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T08:14:54Z","timestamp":1689236094000},"page":"201","source":"Crossref","is-referenced-by-count":3,"title":["Primary Immunodeficiencies in Children Initially Admitted with Gastrointestinal\/Liver Manifestations"],"prefix":"10.5223","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4071-6129","authenticated-orcid":false,"given":"Murat","family":"Cakir","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology Hepatology and Nutrition, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0738-4679","authenticated-orcid":false,"given":"Nalan","family":"Yakici","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3069-2872","authenticated-orcid":false,"given":"Elif","family":"Sag","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Hepatology and Nutrition, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0713-5122","authenticated-orcid":false,"given":"Gulay","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9226-369X","authenticated-orcid":false,"given":"Ay\u015fenur","family":"Bahadir","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7388-874X","authenticated-orcid":false,"given":"Alper Han","family":"Cebi","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4850-932X","authenticated-orcid":false,"given":"Fazil","family":"Orhan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.5223\/pghn.2023.26.4.201_ref1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.iac.2015.07.001","volume":"35","author":"Raje","year":"2015","journal-title":"Immunol Allergy Clin North Am"},{"key":"10.5223\/pghn.2023.26.4.201_ref2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10875-020-00758-x","volume":"40","author":"Bousfiha","year":"2020","journal-title":"J Clin Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s12016-018-8689-9","volume":"57","author":"Hartono","year":"2019","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref4","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jpeds.2004.05.037","volume":"145","author":"Rodrigues","year":"2004","journal-title":"J Pediatr"},{"key":"10.5223\/pghn.2023.26.4.201_ref5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000332076","volume-title":"Concise Pediatric and Adolescent Hepatology","author":"Hadzic","year":"2012"},{"key":"10.5223\/pghn.2023.26.4.201_ref6","unstructured":"ESID Registry - Working definitions for clinical diagnosis of PID. [Internet]. ESID. 2019. cited 2021 Jan 28. Available from: https:\/\/esid.org\/Working-Parties\/Registry-Workingy-Party\/Diagnosis-criteria"},{"key":"10.5223\/pghn.2023.26.4.201_ref7","first-page":"19","volume":"48","author":"Aksu","year":"2006","journal-title":"Turk J Pediatr"},{"key":"10.5223\/pghn.2023.26.4.201_ref8","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.path.2017.07.008","volume":"10","author":"Jessurun","year":"2017","journal-title":"Surg Pathol Clin"},{"key":"10.5223\/pghn.2023.26.4.201_ref9","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/MPG.0b013e3181efe56b","volume":"51","author":"Guerrerio","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.5223\/pghn.2023.26.4.201_ref10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.gtc.2019.02.004","volume":"48","author":"Schwimmer","year":"2019","journal-title":"Gastroenterol Clin North Am"},{"key":"10.5223\/pghn.2023.26.4.201_ref11","doi-asserted-by":"crossref","first-page":"3669","DOI":"10.1038\/s41598-017-03967-4","volume":"7","author":"Lee","year":"2017","journal-title":"Sci Rep"},{"key":"10.5223\/pghn.2023.26.4.201_ref12","doi-asserted-by":"crossref","first-page":"5223","DOI":"10.3390\/ijms21155223","volume":"21","author":"Malesza","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.5223\/pghn.2023.26.4.201_ref13","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1002\/humu.23418","volume":"39","author":"Bourgeois","year":"2018","journal-title":"Hum Mutat"},{"key":"10.5223\/pghn.2023.26.4.201_ref14","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1016\/j.jaip.2020.04.070","volume":"8","author":"Jamee","year":"2020","journal-title":"J Allergy Clin Immunol Pract"},{"key":"10.5223\/pghn.2023.26.4.201_ref15","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.1182\/blood-2011-12-398958","volume":"119","author":"Pagel","year":"2012","journal-title":"Blood"},{"key":"10.5223\/pghn.2023.26.4.201_ref16","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2147\/JMDH.S54802","volume":"8","author":"Reynolds","year":"2015","journal-title":"J Multidiscip Healthc"},{"key":"10.5223\/pghn.2023.26.4.201_ref17","doi-asserted-by":"crossref","first-page":"267","DOI":"10.3389\/fped.2017.00267","volume":"5","author":"Ge","year":"2017","journal-title":"Front Pediatr"},{"key":"10.5223\/pghn.2023.26.4.201_ref18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11882-017-0724-z","volume":"17","author":"Kelsen","year":"2017","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.5223\/pghn.2023.26.4.201_ref19","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/pai.12734","volume":"28","author":"Tegtmeyer","year":"2017","journal-title":"Pediatr Allergy Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref20","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1053\/j.gastro.2014.07.023","volume":"147","author":"Uhlig","year":"2014","journal-title":"Gastroenterology"},{"key":"10.5223\/pghn.2023.26.4.201_ref21","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1159\/000492569","volume":"37","author":"Akkelle","year":"2019","journal-title":"Dig Dis"},{"key":"10.5223\/pghn.2023.26.4.201_ref22","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1016\/j.jaci.2016.09.038","volume":"139","author":"Takagi","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/gastro\/gou082","volume":"3","author":"Rai","year":"2015","journal-title":"Gastroenterol Rep (Oxf)"},{"key":"10.5223\/pghn.2023.26.4.201_ref24","first-page":"15","volume":"9","author":"Yorulmaz","year":"2019","journal-title":"J Contemp Med"},{"key":"10.5223\/pghn.2023.26.4.201_ref25","first-page":"237","volume":"9","author":"Karaca","year":"2010","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref26","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1365-2567.2007.02628.x","volume":"122","author":"Bezrodnik","year":"2007","journal-title":"Immunology"},{"key":"10.5223\/pghn.2023.26.4.201_ref27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00004836-199804000-00008","volume":"26","author":"Fiore","year":"1998","journal-title":"J Clin Gastroenterol"},{"key":"10.5223\/pghn.2023.26.4.201_ref28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jaci.2014.06.001","volume":"134","author":"Hanna","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s12016-019-08756-7","volume":"58","author":"Odineal","year":"2020","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.5223\/pghn.2023.26.4.201_ref30","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1046\/j.1365-2141.2002.03851.x","volume":"119","author":"Gaspar","year":"2002","journal-title":"Br J Haematol"},{"key":"10.5223\/pghn.2023.26.4.201_ref31","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3389\/fped.2020.00577","volume":"8","author":"Khoreva","year":"2020","journal-title":"Front Pediatr"},{"key":"10.5223\/pghn.2023.26.4.201_ref32","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.jhep.2012.03.035","volume":"57","author":"Szabo","year":"2012","journal-title":"J Hepatol"},{"key":"10.5223\/pghn.2023.26.4.201_ref33","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1159\/000452082","volume":"8","author":"Cunniff","year":"2017","journal-title":"Mol Syndromol"}],"container-title":["Pediatric Gastroenterology, Hepatology &amp; Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pghn.org\/pdf\/10.5223\/pghn.2023.26.4.201","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pghn.org\/DOIx.php?id=10.5223\/pghn.2023.26.4.201","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pghn.org\/DOIx.php?id=10.5223\/pghn.2023.26.4.201","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T08:15:24Z","timestamp":1689236124000},"score":1,"resource":{"primary":{"URL":"https:\/\/pghn.org\/DOIx.php?id=10.5223\/pghn.2023.26.4.201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.5223\/pghn.2023.26.4.201","relation":{},"ISSN":["2234-8646","2234-8840"],"issn-type":[{"value":"2234-8646","type":"print"},{"value":"2234-8840","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}