{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:02:01Z","timestamp":1791385321063,"version":"4.3.3"},"reference-count":25,"publisher":"IMR Press","issue":"10","license":[{"start":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T00:00:00Z","timestamp":1635552000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Biosci. (Landmark Ed)"],"abstract":"<jats:p>Introduction: Pneumonia and diarrhoea are amongst the most common causes for hospital admission for children in low- and middle-income countries such as Bangladesh. Undernourished children often have more severe infections and a higher morbidity and mortality. Objective: The objective of this study was to determine the clinical features and outcomes of pneumonia in severely malnourished children with and without diarrhoea. Methodology: A retrospective chart analysis was carried out on children under 5 years of age who were admitted in intensive care unit of the Dhaka hospital of International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b). A total of 245 severe acute malnourished children with pneumonia and diarrhoea (PD group) were compared with 89 children with pneumonia only (PO group). Results: A significantly higher number of children from the PD group had some\/severe dehydration (16.3% vs. 1.1%; p &lt; 0.005) when compared with children from the PO group. The PD group showed less cough (83.3% vs. 100%; p &lt; 0.001), lower chest wall indrawing (40.4% vs. 60.7%; p = 0.001), and crackles (62.4% vs. 87.6%; p &lt; 0.001) compared to the PO group at the time of admission. Conclusion: Early diagnosis and treatment of some\/severe dehydration in addition to WHO recommended other routine treatment of diarrhoea, pneumonia and severe acute malnutrition in children may help to reduce childhood morbidity and mortality especially in low- and middle-income countries.<\/jats:p>","DOI":"10.52586\/4982","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T07:57:21Z","timestamp":1635494241000},"source":"Crossref","is-referenced-by-count":3,"title":["Clinical features of pneumonia in severely malnourished children with diarrhoea compared to those without diarrhoea"],"prefix":"10.31083","volume":"26","author":[{"given":"Sufia","family":"Islam","sequence":"first","affiliation":[{"name":"Department of Pharmacy, East West University, 1212 Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishat","family":"Nasrin","sequence":"first","affiliation":[{"name":"Department of Pharmacy, East West University, 1212 Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigar Sultana","family":"Tithi","sequence":"first","affiliation":[{"name":"Department of Pharmacy, East West University, 1212 Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Lehmann","sequence":"first","affiliation":[{"name":"Department of Anesthesia, Pain Management and Perioperative Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 1X5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammod Jobayer","family":"Chisti","sequence":"first","affiliation":[{"name":"Nutrition & Clinical Services Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), 1212 Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2021,10,30]]},"reference":[{"key":"ref1","unstructured":"UNICEF; WHO; World Bank Group; United Nations. 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Pediatric Clinics of North America. 2016; 63: 67\u201379.","DOI":"10.1016\/j.pcl.2015.08.003"},{"key":"ref10","unstructured":"National Institute of Population Research and Training. Bangladesh Demographic and Health Survey 2017\u201318. 2019. Available at: https:\/\/www.dhsprogram.com\/pubs\/pdf\/PR104\/PR104.pdf (Accessed: 11 June 2021)."},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Chisti MJ, Graham SM, Duke T, Ahmed T, Ashraf H, Faruque ASG, et al. A prospective study of the prevalence of tuberculosis and bacteraemia in Bangladeshi children with severe malnutrition and pneumonia including an evaluation of Xpert MTB\/RIF assay. PLoS ONE. 2014; 9: e93776.","DOI":"10.1371\/journal.pone.0093776"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Chowdhury F, Shahid ASMSB, Ghosh PK, Rahman M, Hassan MZ, Akhtar Z, et al. Viral etiology of pneumonia among severely malnourished under-five children in an urban hospital, Bangladesh. 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Bulletin of the World Health Organization. 1993; 71: 79\u201392."}],"container-title":["Frontiers in Bioscience-Landmark"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.imrpress.com\/journal\/FBL\/26\/10\/10.52586\/4982","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T11:18:26Z","timestamp":1732706306000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/FBL\/26\/10\/10.52586\/4982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,30]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021]]}},"alternative-id":["s2768-6701(21)00041-1"],"URL":"https:\/\/doi.org\/10.52586\/4982","relation":{},"ISSN":["2768-6701","2768-6698"],"issn-type":[{"value":"2768-6701","type":"print"},{"value":"2768-6698","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,30]]},"article-number":"717"}}