{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T18:48:52Z","timestamp":1769366932025,"version":"3.49.0"},"reference-count":106,"publisher":"IMR Press","issue":"12","license":[{"start":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Biosci. (Landmark Ed)"],"abstract":"<jats:p>The fracture of endodontic instruments inside the canal represents a problem that is not always easy to solve. The reutilization of endodontic instruments after sterilization procedures raises the question of how these processes affect their physical and mechanical properties. Alterations can involve the surface of the instruments, as well as their cutting effectiveness, shape and resistance to torsional and cyclic fatigue. The methodology adopted for this systematic review followed the PRISMA guidelines for systematic reviews. The following search terms were used in PubMed and Scopus: \u201cendodontic sterilization\u201d, \u201cendodontic autoclave\u201d, \u201ccyclic fatigue\u201d, \u201ctorsional\u201d, \u201ccutting efficiency\u201d, \u201csterilization\u201d, \u201csurface characteristics\u201d and \u201ccorrosion\u201d. After the screening phase, the application of exclusion criteria and the removal of duplicates, 51 studies were identified and divided into four outcomes: cyclic fatigue; deformation and torsional fatigue; corrosion or surface alterations; and cutting efficiency. Our study of the scientific literature highlights disagreements between studies on these effects. After autoclaving, instruments exhibit a reduction in the cutting efficiency, but NiTi alloy instruments have an improved resistance to cyclic and torsional fatigue.<\/jats:p>","DOI":"10.52586\/5062","type":"journal-article","created":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T01:16:31Z","timestamp":1640913391000},"source":"Crossref","is-referenced-by-count":8,"title":["Influence of sterilization procedures on the physical and mechanical properties of rotating endodontic instruments: a systematic review and network meta-analysis"],"prefix":"10.31083","volume":"26","author":[{"given":"Mario","family":"Dioguardi","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Arena","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Sovereto","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Aiuto","sequence":"first","affiliation":[{"name":"Department of Biomedical, Surgical, and Dental Science, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Laino","sequence":"first","affiliation":[{"name":"Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania \u201cLuigi Vanvitelli\u201d, 80121 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Illuzzi","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrica","family":"Laneve","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna","family":"Raddato","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito Carlo Alberto","family":"Caponio","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Dioguardi","sequence":"first","affiliation":[{"name":"U.S.C.A. \u201cUnit\u00e0 Speciali di Continuit\u00e0 Assistenziale\u201d Troia 2, ASL \u201cAzienda Sanitaria Locale\u201d Foggia Troia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khrystyna","family":"Zhurakivska","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Troiano","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Lo    \n\t\t\t\t\t\tMuzio","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2021,12,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Ataya M, Ha J, Kwak SW, Abu-Tahun IH, El Abed R, Kim H. 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Effect of gamma-ray sterilization on phase transformation behavior and fatigue resistance of contemporary nickel-titanium instruments. Clinical Oral Investigations. 2020; 24: 3113\u20133120.","DOI":"10.1007\/s00784-019-03185-4"},{"key":"ref51","doi-asserted-by":"crossref","unstructured":"Kim W, Oh S, Ryu G, Kim T, Kim S, Kim D, et al. Effect of autoclave sterilization on cyclic fatigue and torsional fracture resistance of NiTi rotary instruments. Odontology. 2020; 108: 194\u2013201.","DOI":"10.1007\/s10266-019-00453-3"},{"key":"ref52","unstructured":"Li X, Zheng P, Xu L, Su Q. The influence of autoclave sterilization on surface characteristics and cyclic fatigue resistance of 3 nickel-titanium rotary instruments. Shanghai Kou Qiang Yi Xue. 2016; 24: 690\u2013695. (In Chinese)"},{"key":"ref53","unstructured":"Yang YJ, Hou BX, Hou XM. Effect of autoclave on surface microstructure and cyclic fatigue resistance of R-phase rotary instruments. 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