{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:56:27Z","timestamp":1788692187496,"version":"build-2803163510"},"reference-count":22,"publisher":"Universa BV","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Orthop Belg"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Rotator cuff tears have a high prevalence in older people. This research examines the clinical outcome of the non-operative treatment of symptomatic degenerative rotator cuff tears with hyaluronic acid (HA) injections.\n\n72 patients (43 females\/29 males), with an average age of 66 years with symptomatic degenerative full- thickness rotator cuff tear, confirmed with arthro-CT, were treated with three intra-articular hyaluronic acid injections and followed on multiple observational moments during a 5-year follow-up using the SF- 36 (Short-Form Health Survey), DASH (Disabilities of the Arm, Shoulder, and Hand), CMS (Constant Murley Score), and OSS (Oxford Shoulder Scale.\n\n54 patients completed the 5-year follow-up questionnaire. 77% of the patients did not require additional treatment for their shoulder pathology, and 89% were treated conservatively. Only 11% of the patients included in this study needed surgery. Between subjects, the analysis revealed a significant difference in response in the DASH (p=0.015) and CMS (p=0.033) when the subscapularis muscle was involved.\n\nIntra-articular infiltrations with hyaluronic acid improve pain and shoulder function, especially if the subscapularis muscle is not involved.<\/jats:p>","DOI":"10.52628\/88.4.10794","type":"journal-article","created":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T22:14:34Z","timestamp":1677968074000},"page":"691-698","source":"Crossref","is-referenced-by-count":4,"title":["Hyaluronic acid as an alternative treatment option for degenerative rotator cuff tears"],"prefix":"10.52628","volume":"88","author":[{"given":"Philip","family":"Tack","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofie","family":"Vanhaverbeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lieven","family":"De Wilde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Van Tongel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27062","published-online":{"date-parts":[[2023,2]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Carbone S, Gumina S, Arceri V, Campagna V, Fagnani C, Postacchini F. 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J Shoulder Elbow Surg 2012;21(6):722-7.","DOI":"10.1016\/j.jse.2011.11.009"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Legre-Boyer V. Viscosupplementation: techniques, indications, results. Orthop Traumatol Surg Res 2015;101(1 Suppl):S101-8.","DOI":"10.1016\/j.otsr.2014.07.027"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Tammi RH, Tammi MI. Hyaluronan accumulation in wounded epidermis: a mediator of keratinocyte activation. J Investigative Dermatol 2009;129(8):1858-60.","DOI":"10.1038\/jid.2009.91"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Chou WY, Ko JY, Wang FS, Huang CC, Wong T, Wang CJ, et al. Effect of sodium hyaluronate treatment on rotator cuff lesions without complete tears: a randomized, double-blind, placebo-controlled study. J Shoulder Elbow Surg 2010;19(4):557-63.","DOI":"10.1016\/j.jse.2009.08.006"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Shibata Y, Midorikawa K, Emoto G, Naito M. 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