{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:33:56Z","timestamp":1786120436182,"version":"build-2736575974"},"reference-count":0,"publisher":"Universa BV","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Orthop Belg"],"abstract":"<jats:p>Unicameral bone cysts (UBCs) are benign fluid-filled bone lesions that primarily affect children and adolescents and carry a clinically relevant risk of pathological fracture. This study explored radiological and clinical variables associated with fracture and recurrence in a histologically confirmed retrospective cohort. Seventy-two patients with histologically confirmed UBCs treated between 2010 and 2021 were retrospectively analysed. Median follow-up was 38 months (range 24-132). Primary outcomes were pathological fracture and radiological recurrence. Because only eight fractures were observed, multivariable analyses were treated as exploratory. Pathological fractures occurred in 8\/72 patients (11.1%). Fracture rates were 0\/46 (0%), 2\/20 (10%) and 6\/6 (100%) for Capanna stages 1, 2 and 3, respectively (p &lt; 0.001). Latent cysts had a higher fracture rate than active cysts (21.4% vs 4.5%; p = 0.049). Recurrence occurred in 7\/71 evaluable patients (9.9%), exclusively in the interventional group (7\/23, 30.4% vs 0\/48; p &lt; 0.001). In this retrospective, histologically selected cohort, higher Capanna stage, younger age, latent activity and diaphyseal localisation were associated with fracture risk. Given the limited number of fracture events, the mixed paediatric-adult population and the selection bias inherent to histological inclusion, these findings are best interpreted as exploratory and hypothesis-generating. Overall, they may be more compatible with structured, individualised risk assessment than with a prescriptive Capanna-guided treatment algorithm.<\/jats:p>","DOI":"10.52628\/92.2.15416","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T21:12:14Z","timestamp":1786050734000},"source":"Crossref","is-referenced-by-count":0,"title":["Multifactorial retrospective analysis of pathological fracture risk and treatment strategies in unicameral bone cysts"],"prefix":"10.52628","volume":"92","author":[{"given":"Y. S.","family":"DURAK","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"KARABAK","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Erzurum City Hospital, Erzurum, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"TOY","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"TUNCER","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, Ozel Medical Park Hospital, Istanbul, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27062","published-online":{"date-parts":[[2026,8]]},"container-title":["Acta Orthopaedica Belgica"],"original-title":[],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T21:12:19Z","timestamp":1786050739000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actaorthopaedica.be\/archive\/volume-92\/summer\/original-clinical-research-oncology\/multifactorial-retrospective-analysis-of-pathological-fracture-risk-and-treatment-strategi\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.52628\/92.2.15416","relation":{},"ISSN":["0001-6462"],"issn-type":[{"value":"0001-6462","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]}}}