{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:17:44Z","timestamp":1747228664796,"version":"3.40.5"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"1","license":[{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>La pancreatitis autoinmune es una forma espec\u00edfica de pancreatitis recurrente y cr\u00f3nica, en cuya etiopatogenia participan mecanismos inmunol\u00f3gicos. Hist\u00f3ricamente se han descripto dos variedades de la enfermedad, cada una de ellas con particularidades cl\u00ednicas, bioqu\u00edmicas e histol\u00f3gicas. En forma reciente fue descripto un tercer subtipo, que es consecuencia de efectos adversos relacionados con el tratamiento con inmunoterapia, la cual tiene indicaci\u00f3n creciente en diversos tumores. El diagn\u00f3stico de la enfermedad es un desaf\u00edo para los profesionales, entre otros motivos debido a su presentaci\u00f3n cl\u00ednica heterog\u00e9nea, que incluye la ictericia obstructiva en la pancreatitis autoinmune tipo 1 y el dolor abdominal en el tipo 2, pudiendo simular patolog\u00edas m\u00e1s graves, como es el adenocarcinoma ductal del p\u00e1ncreas. Los biomarcadores s\u00e9ricos (IgG4) cumplen un papel relevante en el diagn\u00f3stico, pero en ocasiones pueden tener valores normales, en particular en la pancreatitis autoinmune tipo 2, o estar elevados en otras patolog\u00edas. Los m\u00e9todos de estudio por im\u00e1genes no invasivos, en particular la colangio-pancreatografia por resonancia magn\u00e9tica con contraste intravenoso, tienen un rol central en el proceso diagn\u00f3stico de esta enfermedad. En el presente art\u00edculo revisaremos los aspectos imagenol\u00f3gicos de la pancreatitis autoinmune y las manifestaciones extrapancre\u00e1ticas de la enfermedad sist\u00e9mica por IgG4, los rasgos que la diferencian con el c\u00e1ncer de p\u00e1ncreas y los criterios radiol\u00f3gicos de respuesta al tratamiento con corticoides.<\/jats:p>","DOI":"10.52787\/agl.v54i1.392","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T17:31:57Z","timestamp":1718991117000},"page":"14-30","source":"Crossref","is-referenced-by-count":0,"title":["Rol del diagn\u00f3stico por im\u00e1genes en la pancreatitis autoinmune"],"prefix":"10.52787","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3658-3717","authenticated-orcid":false,"given":"Diego","family":"Haberman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0403-6341","authenticated-orcid":false,"given":"Sandra","family":"Basso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Volpacchio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5067-6832","authenticated-orcid":false,"given":"Anal\u00eda","family":"Gubitosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9523-4765","authenticated-orcid":false,"given":"Mar\u00eda Cristina","family":"Nazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6340-8138","authenticated-orcid":false,"given":"Paola","family":"Visbal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1997-2655","authenticated-orcid":false,"given":"Mar\u00eda Florencia","family":"Ranero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"30608","published-online":{"date-parts":[[2024,3,25]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/392\/715","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/392\/730","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/392\/730","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T17:31:59Z","timestamp":1718991119000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,25]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,3,25]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v54i1.392","relation":{},"ISSN":["2469-1119"],"issn-type":[{"type":"print","value":"2469-1119"}],"subject":[],"published":{"date-parts":[[2024,3,25]]}}}