{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T08:56:14Z","timestamp":1783587374859,"version":"3.55.0"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"2","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>Introducci\u00f3n. La constipaci\u00f3n cr\u00f3nica y la incontinencia fecal son trastornos funcionales frecuentes del suelo p\u00e9lvico con alto impacto en la calidad de vida. La Clasificaci\u00f3n de Londres estandariza la evaluaci\u00f3n manom\u00e9trica anorrectal, pero su aplicaci\u00f3n en poblaciones latinoamericanas a\u00fan es escasa.\nObjetivos. Caracterizar los perfiles manom\u00e9tricos anorrectales seg\u00fan la indicaci\u00f3n cl\u00ednica (constipaci\u00f3n, incontinencia fecal o s\u00edntomas coexistentes) empleando la Clasificaci\u00f3n de Londres.\nMateriales y m\u00e9todos. Estudio observacional retrospectivo de 413 pacientes adultos evaluados con manometr\u00eda anorrectal de alta resoluci\u00f3n (Diversatek y ManoScan AR\u00ae) en un centro de atenci\u00f3n terciaria. Se analizaron variables cl\u00ednicas, manom\u00e9tricas y sensoriales clasificadas seg\u00fan los cuatro dominios de la Clasificaci\u00f3n de Londres. En las comparaciones entre grupos se aplicaron ANOVA y chi2.\n Resultados. Los pacientes con constipaci\u00f3n presentaron mayores presiones de reposo y de contracci\u00f3n voluntaria del canal anal, mayor prevalencia de hiperton\u00eda y disinergia, as\u00ed como umbrales sensoriales m\u00e1s altos. En los pacientes con incontinencia fecal predomin\u00f3 la hipoton\u00eda, hipocontractilidad y alteraciones de la coordinaci\u00f3n, sin disinergia. Los casos con s\u00edntomas coexistentes mostraron patrones mixtos. No se hallaron diferencias significativas en la prevalencia del reflejo recto anal inhibitorio ni en los trastornos de la sensibilidad rectal.\nConclusi\u00f3n. La Clasificaci\u00f3n de Londres permiti\u00f3 identificar patrones fisiopatol\u00f3gicos espec\u00edficos seg\u00fan el fenotipo cl\u00ednico. Estos hallazgos podr\u00edan sugerir su utilidad como herramienta diagn\u00f3stica estandarizada, con implicancias cl\u00ednicas para una evaluaci\u00f3n m\u00e1s precisa y personalizada de los trastornos de la defecaci\u00f3n.<\/jats:p>","DOI":"10.52787\/agl.v55i2.492","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T17:18:29Z","timestamp":1751303909000},"page":"124-135","source":"Crossref","is-referenced-by-count":1,"title":["Aplicabilidad de la Clasificaci\u00f3n de Londres para caracterizar los trastornos de la defecaci\u00f3n: estudio retrospectivo en un centro de atenci\u00f3n terciaria de Argentina"],"prefix":"10.52787","volume":"55","author":[{"given":"Mauro","family":"Santana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Marta","family":"Piskorz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Tevez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8112-8860","authenticated-orcid":false,"given":"Fernanda","family":"Gutierrez Arispe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Acquafresca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6524-6931","authenticated-orcid":false,"given":"Tatiana","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"Gonz\u00e1lez Ballerga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge A.","family":"Olmos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30608","published-online":{"date-parts":[[2025,6,30]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/492\/858","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/492\/869","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/492\/869","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T21:57:10Z","timestamp":1754517430000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v55i2.492","relation":{},"ISSN":["2469-1119"],"issn-type":[{"value":"2469-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}