{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:53:38Z","timestamp":1755219218734,"version":"3.43.0"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"2","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>La malabsorci\u00f3n de lactosa y la intolerancia a la lactosa son condiciones frecuentes, cl\u00ednicamente distintas. La malabsorci\u00f3n de lactosa se refiere al paso de este carbohidrato no digerido al colon, debido a deficiencia de lactasa, mientras que la intolerancia implica la aparici\u00f3n de s\u00edntomas gastrointestinales tras su ingesta, en presencia de malabsorci\u00f3n. La alactasia es una forma cong\u00e9nita rara de ausencia total de actividad de la lactasa. La hipolactasia primaria es una reducci\u00f3n fisiol\u00f3gica y gen\u00e9tica de la lactasa en la edad adulta. La prevalencia global de malabsorci\u00f3n alcanza hasta dos tercios de la poblaci\u00f3n, con cifras elevadas en Am\u00e9rica Latina y M\u00e9xico. El diagn\u00f3stico puede realizarse mediante pruebas no invasivas, como la prueba de aliento con lactosa, pruebas gen\u00e9ticas, test de gaxilosa y prueba de tolerancia a la lactosa; o bien mediante m\u00e9todos invasivos como la medici\u00f3n enzim\u00e1tica en biopsias duodenales. El tratamiento debe centrarse en controlar los s\u00edntomas sin comprometer el estado nutricional, mediante dietas bajas en lactosa, suplementos de lactasa ex\u00f3gena y el uso de probi\u00f3ticos o prebi\u00f3ticos. Es fundamental evitar restricciones innecesarias que puedan llevar a deficiencias nutricionales o a trastornos alimentarios, como el de restricci\u00f3n o evitaci\u00f3n de la ingesta de alimentos. Un enfoque diagn\u00f3stico y terap\u00e9utico individualizado mejora la calidad de vida y el manejo cl\u00ednico de estos pacientes.<\/jats:p>","DOI":"10.52787\/agl.v55i2.495","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T17:18:21Z","timestamp":1751303901000},"page":"88-102","source":"Crossref","is-referenced-by-count":0,"title":["Malabsorci\u00f3n e intolerancia a la lactosa"],"prefix":"10.52787","volume":"55","author":[{"given":"Ana L.","family":"Ordo\u00f1ez-V\u00e1zquez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abigail","family":"Fuentes-Montalvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Coss Adame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"30608","published-online":{"date-parts":[[2025,6,30]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/495\/850","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/495\/864","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/495\/864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T21:57:03Z","timestamp":1754517423000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v55i2.495","relation":{},"ISSN":["2469-1119"],"issn-type":[{"type":"print","value":"2469-1119"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}