{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T19:50:17Z","timestamp":1774986617739,"version":"3.50.1"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"1","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>El hemangioendotelioma infantil es el tumor mesenquimatoso benigno m\u00e1s frecuente en el h\u00edgado y se presenta habitualmente en los primeros seis meses de vida. Aunque la alfa-fetoprote\u00edna s\u00e9rica es un marcador tumoral de relevancia significativa en casos de hepatoblastoma, carcinoma hepatocelular y tumores de c\u00e9lulas germinales, en los pacientes con hemangioendotelioma hep\u00e1tico infantil rara vez se observan niveles elevados. En esos casos, dado que los diagn\u00f3sticos diferenciales tienen pron\u00f3sticos diferentes, se deben considerar estrategias diagn\u00f3sticas accesibles con el objetivo de definir conductas. A\u00fan no se ha esclarecido la causa exacta de la elevaci\u00f3n de la alfa-fetoprote\u00edna en el hemangioendotelioma, si bien en algunos estudios se ha demostrado que los hepatocitos atrapados cerca del tumor son los responsables del aumento de los niveles s\u00e9ricos. En este trabajo describimos un caso cl\u00ednico de hemangioendotelioma hep\u00e1tico infantil solitario como presentaci\u00f3n cl\u00ednica poco com\u00fan con elevaci\u00f3n de dicho marcador tumoral.<\/jats:p>","DOI":"10.52787\/agl.v56i1.523","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T18:57:55Z","timestamp":1774983475000},"page":"114-118","source":"Crossref","is-referenced-by-count":0,"title":["Hemangioendotelioma hep\u00e1tico infantil con elevaci\u00f3n de alfa-fetoprote\u00edna: reporte de caso y revisi\u00f3n"],"prefix":"10.52787","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5111-1348","authenticated-orcid":false,"given":"Mar\u00eda Laura","family":"Valberdi Lecce","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5643-8912","authenticated-orcid":false,"given":"Mar\u00eda Cristina","family":"Arregui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen Luc\u00eda","family":"Otegui Banno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6034-0870","authenticated-orcid":false,"given":"Andrea","family":"Besga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"30608","published-online":{"date-parts":[[2026,3,31]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/523\/950","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/523\/969","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/523\/969","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T18:57:56Z","timestamp":1774983476000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,31]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,3,31]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v56i1.523","relation":{},"ISSN":["2469-1119"],"issn-type":[{"value":"2469-1119","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,31]]}}}