{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T02:45:21Z","timestamp":1782873921887,"version":"3.54.5"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"2","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>Introducci\u00f3n. La esofagitis eosinof\u00edlica est\u00e1 escasamente caracterizada en Latinoam\u00e9rica. El objetivo fue estimar su prevalencia y describir las caracter\u00edsticas cl\u00ednicas, endosc\u00f3picas e histol\u00f3gicas, los tratamientos, las tasas de remisi\u00f3n y los factores asociados.\nMateriales y m\u00e9todos. An\u00e1lisis transversal de un registro retrospectivo-prospectivo. Se incluyeron adultos con esofagitis eosinof\u00edlica confirmada entre 2014 y 2025, definida por s\u00edntomas de disfunci\u00f3n esof\u00e1gica y \u226515 eosin\u00f3filos por campo de gran aumento. Los factores asociados a la remisi\u00f3n histol\u00f3gica se exploraron mediante regresi\u00f3n log\u00edstica.\nResultados. Se incluyeron 129 adultos (72,9% varones; mediana de edad, 43 a\u00f1os). La prevalencia fue de 36 por 100.000 afiliados (IC 95%, 27-47) y la mediana de retraso diagn\u00f3stico fue de 8,21 meses. Predominaron la disfagia (75,1%) y la impactaci\u00f3n alimentaria (63,2%). Los hallazgos endosc\u00f3picos m\u00e1s frecuentes fueron surcos (30,4%), edema (24,9%) y anillos (23,4%); el 49% present\u00f3 una endoscop\u00eda normal. Los tratamientos utilizados fueron inhibidores de la bomba de protones (88%), corticoides t\u00f3picos (45%) y dieta de eliminaci\u00f3n (39%). La remisi\u00f3n cl\u00ednica fue del 51,2% y la histol\u00f3gica del 34,3%. La sensibilizaci\u00f3n alimentaria se asoci\u00f3 con remisi\u00f3n histol\u00f3gica (odds ratio ajustado, 3,31; IC 95%, 1,26-8,73; p = 0,015). Entre quienes alcanzaron la remisi\u00f3n histol\u00f3gica, el 28% present\u00f3 una respuesta cl\u00ednica incompleta.\nConclusi\u00f3n. La prevalencia local se ubic\u00f3 en el extremo inferior de la estimaci\u00f3n global agrupada (40,04; IC 95%, 31,10-48,98) y por debajo de la estimaci\u00f3n correspondiente al per\u00edodo 2017-2022 (74,42; IC 95%, 39,66-109,19), as\u00ed como de las cifras contempor\u00e1neas de Estados Unidos y Espa\u00f1a, con las debidas reservas metodol\u00f3gicas y poblacionales. La elevada proporci\u00f3n de endoscop\u00edas normales refuerza la necesidad de realizar biopsias ante la sospecha cl\u00ednica. La remisi\u00f3n histol\u00f3gica en solo un tercio de los casos se\u00f1ala la necesidad de optimizar las estrategias de tratamiento y seguimiento.<\/jats:p>","DOI":"10.52787\/agl.v56i2.631","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T02:05:10Z","timestamp":1782871510000},"page":"196-207","source":"Crossref","is-referenced-by-count":0,"title":["Esofagitis eosinof\u00edlica en una poblaci\u00f3n latinoamericana: resultados de un estudio observacional basado en el registro institucional de un centro de referencia"],"prefix":"10.52787","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7947-270X","authenticated-orcid":false,"given":"J","family":"Arg\u00fcero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Bayarri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6223-1773","authenticated-orcid":false,"given":"L","family":"Bono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8169-171X","authenticated-orcid":false,"given":"Ana","family":"Braslavsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J P","family":"Santino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M L","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M M","family":"Marcolongo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-5599","authenticated-orcid":false,"given":"C A S","family":"Parisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30608","published-online":{"date-parts":[[2026,6,30]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/631\/982","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/631\/993","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/631\/993","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T02:05:10Z","timestamp":1782871510000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,6,30]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v56i2.631","relation":{},"ISSN":["2469-1119"],"issn-type":[{"value":"2469-1119","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]}}}