{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:06:36Z","timestamp":1790863596725,"version":"4.1.0"},"reference-count":0,"publisher":"Sociedad Argentina de Gastroenterologia","issue":"3","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACTA"],"abstract":"<jats:p>Introducci\u00f3n. La fibrosis qu\u00edstica es una patolog\u00eda que requiere diagn\u00f3stico precoz, seguimiento multidisciplinario y acceso a terapias especializadas. La diversidad de los sistemas de salud en Am\u00e9rica Latina podr\u00eda impactar en la calidad de la atenci\u00f3n.\nObjetivo. El objetivo fue describir las pr\u00e1cticas cl\u00ednicas, los recursos diagn\u00f3sticos y el acceso terap\u00e9utico en los centros que atienden fibrosis qu\u00edstica en la regi\u00f3n.\nM\u00e9todos. Estudio transversal descriptivo realizado mediante una encuesta en l\u00ednea aplicada en 2024 a 101 profesionales de la salud de Am\u00e9rica Latina. Se estudiaron las caracter\u00edsticas institucionales, carga asistencial, disponibilidad de cribado neonatal, organizaci\u00f3n multidisciplinaria, m\u00e9todos diagn\u00f3sticos y acceso a moduladores del regulador de la conductancia transmembrana de la fibrosis qu\u00edstica (CFTR).\nResultados. Se analizaron 101 respuestas de profesionales; 52 encuestados (51,5%) trabajaban en centros especializados en fibrosis qu\u00edstica y 49 (48,5%) en centros no especializados, distribuci\u00f3n que corresponde al 100% de la muestra. Los encuestados que trabajaban en centros especializados reportaron una mayor carga de pacientes y equipos multidisciplinarios m\u00e1s completos. El cribado neonatal y la prueba de sudor fueron reportados como disponibles por 58 (57,4%) y 50 (49,5%) de los encuestados, respectivamente. Las pruebas gen\u00e9ticas y los moduladores del regulador de la conductancia transmembrana de la fibrosis qu\u00edstica (CFTR) mostraron una disponibilidad limitada y variable entre pa\u00edses.\n Conclusiones. La atenci\u00f3n de la fibrosis qu\u00edstica en Am\u00e9rica Latina es heterog\u00e9nea. Estandarizar protocolos, fortalecer los centros especializados y mejorar el acceso al diagn\u00f3stico molecular y las terapias avanzadas son prioridades regionales que mejorar\u00edan el diagn\u00f3stico y tratamiento oportuno, as\u00ed como la sobrevida de los pacientes.<\/jats:p>","DOI":"10.52787\/agl.v56i3.583","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:09:21Z","timestamp":1790824161000},"page":"342-351","source":"Crossref","is-referenced-by-count":0,"title":["Fibrosis qu\u00edstica en Am\u00e9rica Latina: pr\u00e1cticas cl\u00ednicas, diagn\u00f3stico y acceso terap\u00e9utico. Estudio transversal multic\u00e9ntrico"],"prefix":"10.52787","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0876-7885","authenticated-orcid":false,"given":"Michelle","family":"Higuera Carrillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5643-8912","authenticated-orcid":false,"given":"Mar\u00eda Cristina","family":"Arregui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5699-8277","authenticated-orcid":false,"given":"Mar\u00eda Soledad","family":"Arcucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6211-7843","authenticated-orcid":false,"given":"Magali","family":"Reyes-Apodaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3479-4139","authenticated-orcid":false,"given":"Elizabeth","family":"Navarro D\u00edaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Violeta","family":"Sereno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0210-7242","authenticated-orcid":false,"given":"Gabriela","family":"Oropeza Gianfelici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magaly","family":"Rodr\u00edguez Guerrero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9858-7369","authenticated-orcid":false,"given":"Mar\u00eda Clara","family":"Jij\u00f3n Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9687-6506","authenticated-orcid":false,"given":"Mario","family":"Alom\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3187-7433","authenticated-orcid":false,"given":"Gustavo","family":"Boldrini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6192-136X","authenticated-orcid":false,"given":"Natali","family":"Gonz\u00e1lez Roz\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8977-2104","authenticated-orcid":false,"given":"Pierangela","family":"Previte Nastasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Ortiz Paranza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30608","published-online":{"date-parts":[[2026,9,30]]},"container-title":["Acta Gastroenterol\u00f3gica Latinoamericana"],"original-title":[],"link":[{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/583\/1006","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/583\/1035","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/download\/583\/1035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:47:10Z","timestamp":1790862430000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaojs.org.ar\/ojs\/index.php\/acta\/article\/view\/583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,9,30]]}},"URL":"https:\/\/doi.org\/10.52787\/agl.v56i3.583","relation":{},"ISSN":["2469-1119"],"issn-type":[{"value":"2469-1119","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]}}}