{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:44:00Z","timestamp":1785426240433,"version":"3.56.0"},"reference-count":85,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Hip fractures are an increasingly common injury in the senior population and almost always require surgical fixation or prosthetic replacement. These surgeries, according to the American Academy of Orthopaedic Surgeons, are considered high-risk for bleeding, especially in a population fraught with comorbidities and often presenting on anticoagulation medications. Direct oral anticoagulants represent a class of drugs that have been becoming more popular in use in this population, with many benefits over the historically used Warfarin. There are recommendations for preoperative discontinuation and postoperative resumption of these medications, which can be more readily managed for elective surgeries. However, there is a paucity of literature detailing best practice guidelines for the perioperative management of direct oral anticoagulants when a patient presents with a hip fracture. This review article summary of the periprocedural management of DOACs for hip surgery was developed by examining the American College of Chest Physicians evidence-based clinical practice guidelines, Perioperative Guidelines on Antiplatelet and Anticoagulant Agents written by anesthesiologists, various retrospective studies, and drug labels for pharmacokinetic data. These recommendations should be used as a guideline, along with the collaboration of multidisciplinary hospital teams during inpatient admission, to manage these complex patients.<\/jats:p>","DOI":"10.52965\/001c.115605","type":"journal-article","created":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:28:44Z","timestamp":1715552924000},"source":"Crossref","is-referenced-by-count":7,"title":["Perioperative Management of Traditional and Direct Oral Anticoagulants in Hip Fracture Patients"],"prefix":"10.52965","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8298-0206","authenticated-orcid":false,"given":"Divesh","family":"Sachdev","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04fegvg32","id-type":"ROR","asserted-by":"publisher"}],"name":"Rosalind Franklin University of Medicine and Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5924-7639","authenticated-orcid":false,"given":"Lafi","family":"Khalil","sequence":"additional","affiliation":[{"name":"McLaren Flint","department":["Department of Orthopaedic Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirollos","family":"Gendi","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital (florida)","department":["Department of Orthopaedic Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Brand","sequence":"additional","affiliation":[{"name":"university of maryland","department":["Department of Orthopaedic Surgery, Division of Traumatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Cominos","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01ythxj32","id-type":"ROR","asserted-by":"publisher"}],"name":"Oakland University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Xie","sequence":"additional","affiliation":[{"name":"bernard j tyson school of medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Mehran","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00t60zh31","id-type":"ROR","asserted-by":"publisher"}],"name":"Kaiser Permanente","department":["Department of Orthopaedic Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2024,5,13]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"publisher","first-page":"2566","DOI":"10.1111\/jth.14977","article-title":"Effect of oral anticoagulants on hemostatic and thromboembolic complications in hip fracture: A systematic review and meta-analysis","volume":"18","author":"Yan Xu","year":"2020","journal-title":"Journal of Thrombosis and Haemostasis","ISSN":"https:\/\/id.crossref.org\/issn\/1538-7836","issn-type":"print"},{"issue":"1","key":"ref2","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.arth.2012.06.001","article-title":"Complications related to therapeutic anticoagulation in total hip arthroplasty","volume":"28","author":"Catherine J. 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