{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T02:10:55Z","timestamp":1781921455216,"version":"3.54.5"},"reference-count":33,"publisher":"Journal of Biological Methods","issue":"1","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HPR"],"abstract":"<jats:p>Background\nOver the past decade, there has been extensive research exploring the relationship between vascular health and mental well-being, encompassing aspects such as mood and cognition. However, there is a notable gap in research focusing on the mental and vascular conditions of minor ischemic stroke or transient ischemic attack (TIA) patients, particularly within the Thai population.\nObjectives\nTo investigate the clinical characteristics and mental issues related to vascular functions in patients who have experienced a minor ischemic stroke or TIA. This study, approved by the Buriram Hospital Ethics Committee (IRB: BR0033.102.1\/8), adhered to the guidelines of the Helsinki Declaration and obtained informed consent from all participants.\nMethods\nA prospective cross-sectional study was conducted at Buriram Hospital, a government regional hospital located in Buriram province, Thailand, involving twenty-three participants diagnosed with minor ischemic stroke or TIA. Measurements included clinical characteristics, Hospital Anxiety and Depression Scale-part Anxiety (HADS-A), Hospital Anxiety and Depression Scale-part Depression (HADS-D), mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), flow-mediated dilation (FMD), and brachial-ankle pulse wave velocity (baPWV). Linear regression analysis was employed to investigate the factors associated with vascular function (FMD and baPWV).\nResults\nThe factor related to FMD was HADS-D (&amp;beta; = -0.5, 95% CI -0.33 to -0.04). Factors associated with baPWV included age (&amp;beta; = 0.51, 95% CI 5.05 to 39.50) and the duration of minor ischemic stroke or TIA (&amp;beta; = 0.48, 95% CI 25.41 to 290.99).\nConclusions\nFMD shows a connection with depressive symptoms in patients with minor ischemic stroke or TIA. Therefore, it is important to detect and provide appropriate treatment for depressive symptoms in these patients, as it may lead to improvements in vascular function and better cerebrovascular outcomes.<\/jats:p>","DOI":"10.52965\/001c.118443","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T22:27:07Z","timestamp":1718144827000},"page":"1","source":"Crossref","is-referenced-by-count":4,"title":["Investigating the Relationship Between Clinical Characteristics, \u00a0 Mental Health, and Vascular Function in Minor Ischemic Stroke or \u00a0 Transient Ischemic Attack Patients"],"prefix":"10.14440","volume":"12","author":[{"given":"Witid","family":"Mitranun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Witoon","family":"Mitarnun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasit","family":"Peepathum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amorntheap","family":"Wandee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenika","family":"Mitarnun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilasinee","family":"Pangwong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanormsak","family":"Senakham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5574","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1161\/CIRCULATIONAHA.109.886655","article-title":"Arterial stiffness and cardiovascular events: the Framingham Heart Study","volume":"121","author":"G.F. 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