{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:55:49Z","timestamp":1790142949916,"version":"4.0.1"},"reference-count":20,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec id=\"background\"> <jats:title>Background<\/jats:title> <jats:p>With the increasing incidence of hip fractures in older adults, hip replacement with a cemented femoral stem has become a viable treatment option. However, concerns regarding potential complications, particularly bone cement implantation syndrome (BCIS), especially in patients with preexisting medical conditions, have prompted orthopedic surgeons to explore alternative approaches.<\/jats:p> <\/jats:sec> <jats:sec id=\"objective\"> <jats:title>Objective<\/jats:title> <jats:p>The research question of this retrospective study is whether BCIS incidence in patients with preexisting heart disease undergoing cemented bipolar hemiarthroplasty is higher than that of patients without preexisting heart disease.<\/jats:p> <\/jats:sec> <jats:sec id=\"methods\"> <jats:title>Methods<\/jats:title> <jats:p>We retrospectively analyzed data from 311 patients undergoing cemented bipolar hemiarthroplasty, including 188 without preexisting heart disease and 123 with heart disease. Anesthetic records were reviewed to assess parameters related to BCIS. BCIS severity was graded systematically, emphasizing key metrics, such as hypotension, arterial desaturation, and the loss of consciousness.<\/jats:p> <\/jats:sec> <jats:sec id=\"results\"> <jats:title>Results<\/jats:title> <jats:p>Among the patients, no perioperative deaths occurred. Grade 1 BCIS was observed in 13 patients (4.18 %), without instances of grade 2 or 3. Notably, grade 1 BCIS was observed in only 2 patients with preexisting heart disease (1.63%) and 11 patients (5.85%) without preexisting heart disease.<\/jats:p> <\/jats:sec> <jats:sec id=\"conclusion\"> <jats:title>Conclusion<\/jats:title> <jats:p>BCIS incidence after cemented bipolar hemiarthroplasty was minimal, with a predominantly low severity. Importantly, preexisting heart disease did not pose a significant increase in the risk of BCIS. This finding confirms the safety of cemented bipolar hemiarthroplasty in older adults.<\/jats:p> <\/jats:sec> <jats:sec id=\"level-of-evidence\"> <jats:title>Level of Evidence<\/jats:title> <jats:p>III<\/jats:p> <\/jats:sec>","DOI":"10.52965\/001c.122320","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T02:35:51Z","timestamp":1724898951000},"source":"Crossref","is-referenced-by-count":5,"title":["Comparative assessment of bone cement implantation syndrome in cemented bipolar hemiarthroplasty: impact in patients with and without preexisting heart disease"],"prefix":"10.52965","volume":"16","author":[{"given":"Varah","family":"Yuenyongviwat","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Faculty of Medicine, Prince of Songkla University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiranuwat","family":"Janejaturanon","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Faculty of Medicine, Prince of Songkla University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theerawit","family":"Hongnaparak","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Faculty of Medicine, Prince of Songkla University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khanin","family":"Iamthanaporn","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Faculty of Medicine, Prince of Songkla University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.3390\/jpm13091381","article-title":"Bone Cement Implantation Syndrome: A Rare Disaster Following Cemented Hip Arthroplasties-Clinical Considerations Supported by Case Studies","volume":"13","author":"F. 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Veldman","year":"2017","journal-title":"Bone Jt J"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.3390\/medicina58111587","article-title":"The Influence of a Modified 3rd Generation Cementation Technique and Vaccum Mixing of Bone Cement on the Bone Cement Implantation Syndrome (BCIS) in Geriatric Patients with Cemented Hemiarthroplasty for Femoral Neck Fractures","volume":"58","author":"U. B\u00f6keler","year":"2022","journal-title":"Med Kaunas Lith"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1055\/a-1738-1777","article-title":"All that Clots Is Not Blood: Bone Cement Implantation Syndrome Presenting as an Intracardiac Mass and Pulmonary Embolism","volume":"122","author":"M.A. Cheong","year":"2022","journal-title":"Thromb Haemost"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00068-020-01587-8","article-title":"Bone cement implantation syndrome in cemented hip hemiarthroplasty\u2014a persistent risk","volume":"48","author":"K. Weing\u00e4rtner","year":"2022","journal-title":"Eur J Trauma Emerg Surg"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"17504589231169861","DOI":"10.1177\/17504589231169861","article-title":"An overview of bone cement: Perioperative considerations, complications, outcomes and future implications","volume":"2023","author":"R. 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