{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T02:18:13Z","timestamp":1785291493115,"version":"3.55.0"},"reference-count":38,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":" Background<\/jats:title> Certain demographics and\/or risk factors contribute to complications following cervical spinal surgery including pseudarthrosis, prolonged pain, and reduced quality of life (QoL). Pulsed electromagnetic field (PEMF) stimulation is a non-invasive therapy that may enhance fusion success in at-risk patients.<\/jats:p> <\/jats:sec> Objective<\/jats:title> To evaluate the safety and efficacy of post-operative adjunctive PEMF therapy following cervical spinal surgery in subjects at risk for pseudarthrosis.<\/jats:p> <\/jats:sec> Methods<\/jats:title> This prospective, multicenter study investigated PEMF as an adjunctive therapy to cervical spinal fusion procedures in subjects at risk for pseudarthrosis based on having at least one of the following: prior failed fusion, multi-level fusion, nicotine use, osteoporosis, or diabetes. Radiographic fusion status and patient-reported outcomes (SF-36, EQ5D, NDI, and VAS-arm pain and VAS-neck pain) were assessed.<\/jats:p> <\/jats:sec> Results<\/jats:title> A total of 160 subjects were assessed for fusion 12-months postoperative, and 144 subjects were successfully fused (90.0%). Fusion success for subjects with 1, 2+, or 3+ risk factors was 91.7%, 89.0%%, and 90.9%, respectively. Significant improvements in NDI, VAS-arm and VAS-neck were observed compared to baseline scores (p < 0.001) along with improvements in SF-36 and EQ5D (p < 0.001).<\/jats:p> <\/jats:sec> Conclusions<\/jats:title> Adjunctive treatment with PEMF provides a high rate of successful fusion and significant improvements in pain, function, and quality of life despite having risk factors for pseudarthrosis.<\/jats:p> <\/jats:sec>","DOI":"10.52965\/001c.122534","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T23:27:02Z","timestamp":1727998022000},"source":"Crossref","is-referenced-by-count":1,"title":["Pulsed Electromagnetic Fields for Cervical Spine Fusion in Patients with Risk Factors for Pseudarthrosis"],"prefix":"10.52965","volume":"16","author":[{"given":"Todd","family":"Lansford","sequence":"first","affiliation":[{"name":"South Carolina Sports Medicine, Charleston, SC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Campbell","sequence":"additional","affiliation":[{"name":"Spine Institute of Louisiana, Shreveport, Louisiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Hassanzadeh","sequence":"additional","affiliation":[{"name":"University of Virginia, Charlottesville, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Florida Orthopedic Institute, Tampa Bay, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Wind","sequence":"additional","affiliation":[{"name":"Inova Neurosurgery, Leesburg, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Beaumont","sequence":"additional","affiliation":[{"name":"Aspirus Spine and Neurosciences Institute, Wausau, Wisconsin, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Vokshoor","sequence":"additional","affiliation":[{"name":"Institute of Neuro Innovation, Santa Monica, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Radcliff","sequence":"additional","affiliation":[{"name":"Rothman Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilyas","family":"Aleem","sequence":"additional","affiliation":[{"name":"University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domagoj","family":"Coric","sequence":"additional","affiliation":[{"name":"Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2024,10,3]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1302\/2046-3758.1012.BJR-2021-0274.R1","article-title":"High slew rate pulsed electromagnetic field enhances bone consolidation and shortens daily treatment duration in distraction osteogenesis","volume":"10","author":"Y., et al. 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