{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:09:40Z","timestamp":1785409780078,"version":"3.56.0"},"reference-count":11,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Introduction<\/jats:title>\n Interlaminar epidural steroid injections (ILESIs) using a parasagittal approach are frequently employed to manage lumbar radicular pain. The degree of contralateral symptom relief achieved with parasagittal ILESIs remains underexplored. This study aims to evaluate the short-term effectiveness of parasagittal ILESIs in providing ipsilateral and contralateral symptom relief in patients with bilateral lumbar radiculopathy and unilateral contrast spread.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A retrospective review was conducted on 12 patients with bilateral lumbar radicular symptoms who underwent parasagittal ILESIs under fluoroscopic guidance. Patient-reported symptom relief was assessed for both ipsilateral and contralateral sides at a two-week follow-up visit or phone call. Descriptive statistics were used to evaluate patterns in symptom relief across the cohort.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n All patients experienced significant relief on the ipsilateral side, with reported improvement ranging from 60% to 100% (mean: 84.6%). Contralateral relief was more variable, ranging from 0% to 90% (mean: 37.5%). No complications were reported.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Parasagittal ILESIs provide more consistent and substantial relief of ipsilateral lumbar radicular symptoms. Contralateral relief is less predictable and may be limited by needle placement and the spread of medication. These findings support the use of parasagittal ILESIs in cases of unilateral or dominant-side radicular pain. For patients with significant bilateral symptoms, midline ILESIs or bilateral transforaminal injections may be more effective. Further prospective studies are warranted to identify predictors of bilateral relief and optimize procedural technique.<\/jats:p>\n <\/jats:sec>","DOI":"10.52965\/001c.143088","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:40:59Z","timestamp":1755132059000},"source":"Crossref","is-referenced-by-count":2,"title":["Evaluating Bilateral Symptom Relief Following Parasagittal Interlaminar Epidural Steroid Injections"],"prefix":"10.52965","volume":"17","author":[{"given":"Jamal","family":"Hasoon","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03gds6c39","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Texas Health Science Center at Houston","department":["Department of Anesthesiology, Critical Care and Pain Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L","family":"Robinson","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04b6nzv94","id-type":"ROR","asserted-by":"publisher"}],"name":"Brigham and Women's Hospital","department":["Department of Anesthesiology, Perioperative, and Pain Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Viswanath","sequence":"additional","affiliation":[{"name":"Mountain View Headache and Spine Institute"},{"name":"Creighton University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Urits","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01mgpsx86","id-type":"ROR","asserted-by":"publisher"}],"name":"SouthCoast Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan D","family":"Kaye","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03151rh82","id-type":"ROR","asserted-by":"publisher"}],"name":"Louisiana State University Health Sciences Center Shreveport","department":["Department of Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"publisher","first-page":"e78817","DOI":"10.7759\/cureus.78817","article-title":"Patient Outcomes Following Parasagittal Interlaminar Epidural Steroid Injections for Bilateral Lumbar Radicular Symptoms: Correlation of Contrast Spread With Symptom Relief","volume":"17","author":"J. Hasoon","year":"2025","journal-title":"Cureus"},{"issue":"1","key":"ref2","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s11916-025-01396-x","article-title":"Epidural Contrast Patterns and Clinical Implications: An Educational Review","volume":"29","author":"G. L. Bianco","year":"2025","journal-title":"Curr Pain Headache Rep"},{"issue":"9","key":"ref3","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.bjae.2022.05.003","article-title":"Lumbar radicular pain","volume":"22","author":"H. Soar","year":"2022","journal-title":"BJA Educ"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"27","DOI":"10.36076\/ppj.2021.24.S27-S208","article-title":"Epidural interventions in the management of chronic spinal pain: American Society of Interventional Pain Physicians (ASIPP) comprehensive evidence-based guidelines","volume":"24","author":"L. Manchikanti","year":"2021","journal-title":"Pain Physician"},{"issue":"2","key":"ref5","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.pmr.2022.01.009","article-title":"Epidural Steroid Injections","volume":"33","author":"J. William","year":"2022","journal-title":"Phys Med Rehabil Clin N Am"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"138210","DOI":"10.52965\/001c.138210","article-title":"Understanding the Landscape of Lumbar Epidural Steroid Injections: A Review of Interlaminar, Transforaminal, and Caudal Approaches","volume":"17","author":"T. Li","year":"2025","journal-title":"Orthop Rev (Pavia)"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"123283","DOI":"10.52965\/001c.123283","article-title":"Practice Patterns of Physicians who Perform Caudal Epidural Steroid Injections","volume":"16","author":"A. Brown","year":"2024","journal-title":"Orthop Rev (Pavia)"},{"issue":"2","key":"ref8","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1111\/papr.13297","article-title":"A systematic review and network meta-analysis comparing different epidural steroid injection approaches","volume":"24","author":"A. M. Mahmoud","year":"2024","journal-title":"Pain Pract"},{"issue":"6","key":"ref9","doi-asserted-by":"publisher","first-page":"729","DOI":"10.3390\/diagnostics15060729","article-title":"Preprocedural Imaging Review Before Performing Epidural Steroid Injections: Analysis of Physician Practice Parameters","volume":"15","author":"J. Hasoon","year":"2025","journal-title":"Diagnostics (Basel)"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"676730","DOI":"10.3389\/fpain.2021.676730","article-title":"Parasagittal Approach of Epidural Steroid Injection as a Treatment for Chronic Low Back Pain: A Systematic Review and Meta-Analysis","volume":"2","author":"N. N. Knezevic","year":"2021","journal-title":"Front Pain Res (Lausanne)"},{"issue":"1","key":"ref11","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1213\/ANE.0b013e3182910a15","article-title":"Lateral parasagittal versus midline interlaminar lumbar epidural steroid injection for management of low back pain with lumbosacral radicular pain: a double-blind, randomized study","volume":"117","author":"B. Ghai","year":"2013","journal-title":"Anesth Analg"}],"container-title":["Orthopedic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/143088-evaluating-bilateral-symptom-relief-following-parasagittal-interlaminar-epidural-steroid-injections","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T00:59:35Z","timestamp":1761440375000},"score":1,"resource":{"primary":{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/143088-evaluating-bilateral-symptom-relief-following-parasagittal-interlaminar-epidural-steroid-injections"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":11,"URL":"https:\/\/doi.org\/10.52965\/001c.143088","relation":{},"ISSN":["2035-8164"],"issn-type":[{"value":"2035-8164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]}}}