{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:32:04Z","timestamp":1785418324412,"version":"3.56.0"},"reference-count":26,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Pancoast tumors are a rare form of non-small cell lung cancers located in the lung apex invading thoracic inlet structures and surrounding tissues. This case focuses on a 71-year-old male smoker who presented with chronic neck pain and weakness in his right arm. Imaging revealed a mass in the right lung apex that had spread to the ribs, vertebrae, and brachial plexus. A biopsy confirmed squamous cell carcinoma. Initial treatment includes chemoradiation, especially in cases where surgical resection is not recommended due to invasion of critical structures. Early recognition is crucial to avoid disease progression and to initiate appropriate oncologic management. This case emphasizes the need to consider Pancoast tumors in patients with ongoing neck and upper limb neurological symptoms, even if they do not have respiratory issues, to ensure quick diagnosis and treatment.<\/jats:p>","DOI":"10.52965\/001c.143289","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T15:26:11Z","timestamp":1755703571000},"source":"Crossref","is-referenced-by-count":1,"title":["Pancoast tumor masquerading as musculoskeletal pain"],"prefix":"10.52965","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5832-4892","authenticated-orcid":false,"given":"Pranay","family":"Gadikota","sequence":"first","affiliation":[{"name":"Buchholz HS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7715-4045","authenticated-orcid":false,"given":"Vindhya N.","family":"Reddy","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02f65mn87","id-type":"ROR","asserted-by":"publisher"}],"name":"Apollo Institute of Medical Sciences & Research"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7717-3864","authenticated-orcid":true,"given":"Latha","family":"Ganti","sequence":"additional","affiliation":[{"name":"The Warren Alpert Medical School of Brown University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"issue":"5","key":"ref1","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1016\/j.radcr.2024.01.091","article-title":"Deciphering the enigmatic symptoms of Pancoast tumors: Navigating the complex landscape of pain management-A case report","volume":"19","author":"L. Ko\u010dan","year":"2024","journal-title":"Radiol Case Rep"},{"issue":"2","key":"ref2","doi-asserted-by":"publisher","first-page":"179","DOI":"10.3171\/spi.2004.1.2.0179","article-title":"Cervical radiculopathy, entrapment neuropathy, and thoracic outlet syndrome: how to differentiate? Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004","volume":"1","author":"J. E. McGillicuddy","year":"2004","journal-title":"J Neurosurg Spine"},{"key":"ref3","series-title":"StatPearls [Internet]","article-title":"Horner Syndrome","author":"Z. Khan","year":"2025"},{"issue":"5","key":"ref4","doi-asserted-by":"publisher","first-page":"e15328","DOI":"10.7759\/cureus.15328","article-title":"A Nearly Missed Pancoast Tumour From Isolated Persistent Leg Pain","volume":"13","author":"M. Issa","year":"2021","journal-title":"Cureus"},{"issue":"1","key":"ref5","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s13256-022-03328-4","article-title":"Pancoast tumor presenting with multiple joint pains: a case report","volume":"16","author":"S. Mohamud","year":"2022","journal-title":"J Med Case Rep"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"239","DOI":"10.21037\/atm.2016.06.16","article-title":"Superior sulcus tumors (Pancoast tumors)","volume":"4","author":"G. Marulli","year":"2016","journal-title":"Ann Transl Med"},{"issue":"3 and 4","key":"ref7","first-page":"63","article-title":"A case report of Pancoast tumor presenting as cervical radiculopathy","volume":"3","author":"R. Abdi","year":"2015","journal-title":"J Surg Trauma"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e937052","DOI":"10.12659\/AJCR.937052","article-title":"Pancoast Tumor Presenting as Neck Pain in the Chiropractic Office: A Case Report and Literature Review","volume":"23","author":"E. C. Chu","year":"2022","journal-title":"Am J Case Rep"},{"issue":"2","key":"ref9","doi-asserted-by":"publisher","first-page":"115809","DOI":"10.56305\/001c.115809","article-title":"Pancoast Syndrome Due to Metastatic Hepatocellular Carcinoma","volume":"3","author":"M. C. Slack","year":"2024","journal-title":"J Brown Hosp Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.xjtc.2024.04.005","article-title":"Current management of anterior Pancoast tumors","volume":"25","author":"E. Fadel","year":"2024","journal-title":"JTCVS Tech"},{"issue":"2","key":"ref11","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3126\/njms.v2i2.8973","article-title":"Pancoast Tumor Masquerading as Cervical Spondylosis: a Case Report","volume":"2","author":"M.K. Gupta","year":"2013","journal-title":"Nepal Journal of Medical Sciences"},{"issue":"20","key":"ref12","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.21037\/atm-21-4698","article-title":"Surgical resection of superior pulmonary sulcus tumor after neoadjuvant chemoradiation via the anterior transmanubrial approach: a case report","volume":"9","author":"F. Bao","year":"2021","journal-title":"Ann Transl Med"},{"issue":"Suppl 1","key":"ref13","doi-asserted-by":"publisher","first-page":"S180","DOI":"10.3978\/j.issn.2072-1439.2013.12.31","article-title":"Therapeutic modalities for Pancoast tumors","volume":"6","author":"P. Nikolaos","year":"2014","journal-title":"J Thorac Dis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/1749-8090-5-102","article-title":"Treatment of pancoast tumors from the surgeons prospective: re-appraisal of the anteriormanubrial sternal approach","volume":"5","author":"H. Parissis","year":"2010","journal-title":"J Cardiothorac Surg"},{"issue":"1","key":"ref15","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/S0003-4975(98)00374-9","article-title":"Superior sulcus (Pancoast) tumor: experience with 105 patients","volume":"66","author":"S. Attar","year":"1998","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"ref16","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1067\/mtc.2000.106089","article-title":"Factors determining outcome after surgical resection of T3 and T4 lung cancers of the superior sulcus","volume":"119","author":"V. W. Rusch","year":"2000","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"19","key":"ref17","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1056\/NEJM199711063371907","article-title":"Superior pulmonary sulcus tumors and Pancoast's syndrome","volume":"337","author":"S. M. Arcasoy","year":"1997","journal-title":"N Engl J Med"},{"issue":"6","key":"ref18","doi-asserted-by":"publisher","first-page":"1990","DOI":"10.1016\/S0003-4975(03)00134-6","article-title":"Changes in the treatment of Pancoast tumors","volume":"75","author":"F. C. Detterbeck","year":"2003","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"ref19","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1177\/107327481402100209","article-title":"Management of locally advanced Pancoast (superior sulcus) tumors with spine involvement","volume":"21","author":"M. Setzer","year":"2014","journal-title":"Cancer Control"},{"key":"ref20","series-title":"StatPearls [Internet]","article-title":"Lung Pancoast Tumor","author":"S. G. Gundepalli","year":"2025"},{"issue":"Suppl 4","key":"ref21","doi-asserted-by":"publisher","first-page":"S342","DOI":"10.3978\/j.issn.2072-1439.2013.04.08","article-title":"Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment","volume":"5","author":"C. N. Foroulis","year":"2013","journal-title":"J Thorac Dis"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1001\/jama.1932.02740690001001","article-title":"Superior pulmonary sulcus tumor: tumor characterized by pain Horner's syndrome, destruction of bone and atrophy of hand muscles","volume":"19","author":"H. K. Pancoast","year":"1932","journal-title":"JAMA"},{"key":"ref23","first-page":"663","article-title":"[Misdiagnosis of pancoast cancer: Analysis of 26 cases]","volume":"34","author":"P. Deng","year":"2011","journal-title":"Zhonghua Jie He He Hu Xi Za Zhi"},{"key":"ref24","article-title":"NICE Clinical Guidelines (CG 121) April 2011- diagnosing and treatment of lung cancer","year":"2011"},{"key":"ref25","first-page":"863","article-title":"Delay in diagnosis of lung cancer in general practice","volume":"56","author":"M. Bjerager","year":"2006","journal-title":"Br J Gen Pract"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"S108","DOI":"10.3978\/j.issn.2072-1439.2013.12.29","article-title":"Pancoast tumors: Characteristics and preoperative assessment","volume":"6","author":"N. Panagopoulos","year":"2014","journal-title":"J Thorac Dis"}],"container-title":["Orthopedic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/143289-pancoast-tumor-masquerading-as-musculoskeletal-pain","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T00:59:39Z","timestamp":1761440379000},"score":1,"resource":{"primary":{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/143289-pancoast-tumor-masquerading-as-musculoskeletal-pain"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,20]]},"references-count":26,"URL":"https:\/\/doi.org\/10.52965\/001c.143289","relation":{},"ISSN":["2035-8164"],"issn-type":[{"value":"2035-8164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,20]]}}}