{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T01:05:08Z","timestamp":1761440708608,"version":"build-2065373602"},"reference-count":18,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Background<\/jats:title>\n Osteogenesis Imperfecta (OI) is a rare genetic bone disorder that has attracted increasing scientific attention. Bibliometric analysis offers insights into the intellectual structure and evolution of this field. This study aimed to identify and evaluate the most highly cited articles on OI to highlight influential contributors, leading journals, and major research trends.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A bibliometric search was conducted in the Web of Science Core Collection using the terms \u201cOsteogenesis Imperfecta\u201d and \u201cBrittle Bone Disease.\u201d The search was restricted to English- language original and review articles published between 2000 and 2024. The 50 most cited articles were selected and analyzed based on citation metrics, journal impact factors, author contributions, institutional affiliations, and collaboration patterns. Statistical analyses were performed using SPSS version 25.0.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The United States produced the highest number of publications, followed by the United Kingdom and Germany. The most cited article, published by Rauch et al.\u00a0(2004), received 950 citations. The Journal of Bone and Mineral Research and The American Journal of Human Genetics were the most prolific journals in this domain. Observational studies and genetic investigations dominated the top-cited works. Collaboration networks revealed strong interconnections among North American and European institutions, while keyword analysis highlighted growing research interest in gene therapy, molecular diagnostics, and precision medicine.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This bibliometric analysis identified the most influential contributions in OI research, underscoring the role of key authors, journals, and international collaborations. It also revealed major trends in genetic and clinical studies while highlighting emerging areas such as gene therapy and precision medicine as promising directions for future research.<\/jats:p>\n <\/jats:sec>","DOI":"10.52965\/001c.144737","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T19:07:00Z","timestamp":1759172820000},"source":"Crossref","is-referenced-by-count":0,"title":["Comprehensive Bibliometric Assessment of the Top 50 Cited Articles on Osteogenesis Imperfecta"],"prefix":"10.52965","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2369-9467","authenticated-orcid":false,"given":"Abdulmohsen S.","family":"Alanazi","sequence":"first","affiliation":[{"name":"College of Medicine, Imam Mohammed Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.","department":["General Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulelah F.","family":"Alshehri","sequence":"additional","affiliation":[{"name":"College of Medicine, Imam Mohammed Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.","department":["General Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6271-5079","authenticated-orcid":false,"given":"Khalaf A.","family":"Alnowaishiri","sequence":"additional","affiliation":[{"name":"Kuwait Institute for Medical Specializations (KIMS), Kuwait City, Kuwait.","department":["Medical Department"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7007-0065","authenticated-orcid":false,"given":"Jamla S.","family":"Al-Hajri","sequence":"additional","affiliation":[{"name":"College of Health Science, Qatar University, Doha, Qatar.","department":["Department of Biomedical Sciences"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7717-5822","authenticated-orcid":false,"given":"Khalid A.","family":"Rifadah","sequence":"additional","affiliation":[{"name":"College of Medicine, University of Tabuk, Tabuk, Saudi Arabia.","department":["General Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3705-4313","authenticated-orcid":false,"given":"Bayan K.","family":"Alanazi","sequence":"additional","affiliation":[{"name":"College of Medicine, Imam Mohammed Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.","department":["General Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0993-3468","authenticated-orcid":false,"given":"Mansour M.","family":"AlGhufaynah","sequence":"additional","affiliation":[{"name":"King Saud Medical City, Riyadh, Saudi Arabia.","department":["Department of Orthopedics"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6378-4566","authenticated-orcid":false,"given":"Ali M.","family":"Aldossari","sequence":"additional","affiliation":[{"name":"Ministry of Health, King Saud Medical City \u2013 Riyadh, Saudi Arabia.","department":["Pediatric Orthopedic"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"30777","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/genes16040416","article-title":"The Spectra of Pathogenic Variants and Phenotypes in a Chinese Cohort of 298 Families with Osteogenesis Imperfecta","volume":"16","author":"S., et al. 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Jovanovic","year":"2024","journal-title":"Calcif Tissue Int"}],"container-title":["Orthopedic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/144737-comprehensive-bibliometric-assessment-of-the-top-50-cited-articles-on-osteogenesis-imperfecta","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T00:59:59Z","timestamp":1761440399000},"score":1,"resource":{"primary":{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/144737-comprehensive-bibliometric-assessment-of-the-top-50-cited-articles-on-osteogenesis-imperfecta"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":18,"URL":"https:\/\/doi.org\/10.52965\/001c.144737","relation":{},"ISSN":["2035-8164"],"issn-type":[{"type":"electronic","value":"2035-8164"}],"subject":[],"published":{"date-parts":[[2025,9,29]]}}}