{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T11:30:03Z","timestamp":1785583803659,"version":"3.56.0"},"reference-count":14,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Introduction<\/jats:title>\n Trigeminal neuralgia is a debilitating facial pain condition characterized by recurrent, electric shock-like episodes within the trigeminal nerve distribution. While first-line treatment involves pharmacologic therapy, treatment options are limited for patients who are refractory or poor surgical candidates.<\/jats:p>\n <\/jats:sec>\n \n Case Presentation<\/jats:title>\n We present a 75-year-old female with long-standing idiopathic trigeminal neuralgia refractory to combination anticonvulsant therapy and nerve block, with notable medication-related side effects.<\/jats:p>\n <\/jats:sec>\n \n Management and Outcomes<\/jats:title>\n The patient underwent percutaneous cryoneurolysis targeting the maxillary (V2) and mandibular (V3) divisions of the trigeminal nerve under fluoroscopic guidance. She experienced immediate pain reduction and complete symptom resolution at a one-month follow-up with no complications.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case highlights percutaneous cryoneurolysis as a minimally invasive treatment option for selected patients with refractory trigeminal neuralgia who are not candidates for open surgical intervention.<\/jats:p>\n <\/jats:sec>","DOI":"10.52965\/001c.158567","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:52:19Z","timestamp":1776127939000},"source":"Crossref","is-referenced-by-count":1,"title":["Use of Cryoneurolysis Therapy for the Management of Idiopathic Trigeminal Neuralgia"],"prefix":"10.52965","volume":"18","author":[{"given":"Karina","family":"Gritsenko","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/044ntvm43","id-type":"ROR","asserted-by":"publisher"}],"name":"Montefiore Medical Center","department":["Anesthesiology"]},{"id":[{"id":"https:\/\/ror.org\/05cf8a891","id-type":"ROR","asserted-by":"publisher"}],"name":"Albert Einstein College of Medicine","department":["Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Mi","family":"Oh","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/044ntvm43","id-type":"ROR","asserted-by":"publisher"}],"name":"Montefiore Medical Center","department":["Anesthesiology"]},{"id":[{"id":"https:\/\/ror.org\/05cf8a891","id-type":"ROR","asserted-by":"publisher"}],"name":"Albert Einstein College of Medicine","department":["Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukhlisa","family":"Zakirova","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02bxt4m23","id-type":"ROR","asserted-by":"publisher"}],"name":"Northwell Health","department":["Internal Medicine"]},{"id":[{"id":"https:\/\/ror.org\/00c8v4891","id-type":"ROR","asserted-by":"publisher"}],"name":"Long Island Jewish Medical Center","department":["Internal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole Rene","family":"Ortiz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/044ntvm43","id-type":"ROR","asserted-by":"publisher"}],"name":"Montefiore Medical Center","department":["Physical Medicine and Rehabilitation"]},{"id":[{"id":"https:\/\/ror.org\/05cf8a891","id-type":"ROR","asserted-by":"publisher"}],"name":"Albert Einstein College of Medicine","department":["Physical Medicine and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagun","family":"Raghavan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00rs6vg23","id-type":"ROR","asserted-by":"publisher"}],"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarang","family":"Koushik","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02qp3tb03","id-type":"ROR","asserted-by":"publisher"}],"name":"Mayo Clinic","department":["Anesthesiology"]},{"name":"Creighton University School of Medicine","department":["Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Viswanath","sequence":"additional","affiliation":[{"name":"Creighton University School of Medicine","department":["Anesthesiology"]},{"name":"Mountain View Headache and Spine Institute","department":["Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naum","family":"Shaparin","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/044ntvm43","id-type":"ROR","asserted-by":"publisher"}],"name":"Montefiore Medical Center","department":["Anesthesiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"ref1","article-title":"Comparison of Nerve Treatments","author":"Pacira Pharmaceuticals, Inc.","year":"2024","journal-title":"Iovera"},{"issue":"2","key":"ref2","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1002\/mus.24306","article-title":"Wallerian degeneration and recovery of motor nerves after multiple focused cold therapies","volume":"51","author":"M. 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