{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:57:56Z","timestamp":1786373876731,"version":"build-2736575974"},"reference-count":31,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec id=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cephalomedullary nails (CMNs) are frequently utilized for subtrochanteric femur fractures but a lack of cortical fit in proximal fractures may lead to varus deformity. We hypothesize that as the difference between fracture site canal width and diameter of the nail increases so will the risk of varus deformity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study of subtrochanteric femur fractures fixed with CMNs at an academic, level one trauma center over a 6.5-year period was performed. Patients were divided into two cohorts: CMN with sliding blade\/screw (TFNA) or greater trochanteric entry recon nail (GTE). The primary outcome analyzed was the correlation between nail-canal mismatch with final neck shaft angle. Secondary outcomes analyzed included rates of nonunion and malunion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-one patients met the inclusion criteria (35 TFNA and 36 GTE). There was not a significant correlation between the nail-canal mismatch with final neck shaft angle for GTE nails (Pearson correlation coefficient r: -0.187, p=0.274). However, when TFNAs were subdivided into 125\u00b0 and 130\u00b0 cohorts, there was a stronger negative correlation for 125\u00b0 (r: -0.678, p=0.001) compared to the 130\u00b0 (r: -0.515, p=0.041). For 125\u00b0 TFNAs, linear regression analysis demonstrated that for every 1 mm increase in nail-canal mismatch there was a decrease in final neck shaft angle by 0.757\u2070. There was no difference in secondary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"conclusion\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>GTE nails and TFNAs have similar rates of malunion and nonunion when managing subtrochanteric femur fractures. However, 125\u00b0 TFNAs may be associated with increased varus neck shaft angles as the nail-canal mismatch increases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.52965\/001c.166437","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T13:51:15Z","timestamp":1786369875000},"source":"Crossref","is-referenced-by-count":0,"title":["Does Cephalomedullary Nail Design Influence Risk of Varus Collapse in Subtrochanteric Femur Fractures?"],"prefix":"10.52965","volume":"18","author":[{"given":"Momin","family":"Ahmed","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02y3ad647","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Florida","department":["College of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Mickley","sequence":"additional","affiliation":[{"name":"University of Florida College of Medicine Jacksonville","department":["Department of Orthopedic Surgery and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Lopez","sequence":"additional","affiliation":[{"name":"University of Florida College of Medicine Jacksonville","department":["Department of Orthopedic Surgery and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Baki","sequence":"additional","affiliation":[{"name":"University of Florida College of Medicine Jacksonville","department":["Department of Orthopedic Surgery and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Moses","sequence":"additional","affiliation":[{"name":"University of Florida College of Medicine Jacksonville","department":["Department of Orthopedic Surgery and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8820-2146","authenticated-orcid":true,"given":"Porter","family":"Young","sequence":"additional","affiliation":[{"name":"University of Florida College of Medicine Jacksonville","department":["Department of Orthopedic Surgery and Rehabilitation"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1097\/00005373-199402000-00011","article-title":"Intramedullary nailing of femoral fractures in morbidly obese patients","volume":"36","author":"M. 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Ostrum","year":"2005","journal-title":"J Orthop Trauma"},{"issue":"8","key":"ref5","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/S0020-1383(02)00158-4","article-title":"Antegrade femoral nailing: an anatomical determination of the correct entry point","volume":"33","author":"T. Gausepohl","year":"2002","journal-title":"Injury"},{"issue":"6","key":"ref6","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1080\/17453670610013196","article-title":"Anatomy of the greater femoral trochanter: clinical importance for intramedullary femoral nailing. Anatomic study of 100 cadaver specimens","volume":"77","author":"W. Grechenig","year":"2006","journal-title":"Acta Orthop"},{"issue":"4","key":"ref7","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1097\/BOT.0000000000001096","article-title":"Does the Angle of the Nail Matter for Pertrochanteric Fracture Reduction? Matching Nail Angle and Native Neck-Shaft Angle","volume":"32","author":"J. A. Parry","year":"2018","journal-title":"J Orthop Trauma"},{"issue":"4","key":"ref8","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1097\/BOT.0000000000001670","article-title":"Impact of Surrounding Canal Size on Time to Union After Intramedullary Nailing of Femur Fractures: Are 10-mm Nails All We Need?","volume":"34","author":"R. S. Yoon","year":"2020","journal-title":"J Orthop Trauma"},{"issue":"11","key":"ref9","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1097\/BOT.0000000000001585","article-title":"Effect of Nail Size, Insertion, and \u0394 Canal-Nail on the Development of a Nonunion After Intramedullary Nailing of Femoral Shaft Fractures","volume":"33","author":"R. Serrano","year":"2019","journal-title":"J Orthop Trauma"},{"issue":"1","key":"ref10","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1186\/s12891-022-05781-0","article-title":"Does nail size or difference between canal and nail diameter influence likelihood of union or time to union of femoral shaft fractures treated with intramedullary nailing? A retrospective cohort study","volume":"23","author":"C. Y. Shih","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"issue":"4","key":"ref11","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1097\/00005131-200604000-00002","article-title":"Cephalomedullary nails in the treatment of high-energy proximal femur fractures in young patients: a prospective, randomized comparison of trochanteric versus piriformis fossa entry portal","volume":"20","author":"A. J. Starr","year":"2006","journal-title":"J Orthop Trauma"},{"issue":"4","key":"ref12","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1016\/j.injury.2022.01.038","article-title":"Intramedullary nailing of subtrochanteric fractures in elderly patients: Comparative study of helical blade cephalomedullary nail versus reconstruction nail","volume":"53","author":"Y. C. Yoon","year":"2022","journal-title":"Injury"},{"issue":"1","key":"ref13","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.3928\/01477447-20111122-02","article-title":"Comparative study of the proximal femoral nail antirotation versus the reconstruction nail in the treatment of comminuted proximal femoral fracture","volume":"35","author":"F. T. Huang","year":"2012","journal-title":"Orthopedics"},{"issue":"4","key":"ref14","doi-asserted-by":"publisher","first-page":"e426","DOI":"10.1097\/OI9.0000000000000426","article-title":"Biomechanical comparison of cephalomedullary and reconstruction nails used in the treatment of subtrochanteric femur fractures","volume":"8","author":"J. McKeeman","year":"2025","journal-title":"OTA Int"},{"issue":"6","key":"ref15","doi-asserted-by":"publisher","first-page":"111512","DOI":"10.1016\/j.injury.2024.111512","article-title":"Comparative biomechanical analysis of reconstruction and cephalomedullary nails in the treatment of osteoporotic subtrochanteric fractures","volume":"55","author":"Y. C. Yoon","year":"2024","journal-title":"Injury"},{"issue":"6","key":"ref16","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1007\/s00402-019-03131-9","article-title":"Risk factors for nonunion after intramedullary nailing of subtrochanteric femoral fractures","volume":"139","author":"D. 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Wang","year":"2021","journal-title":"Medicine (Baltimore)"},{"issue":"23","key":"ref19","doi-asserted-by":"publisher","first-page":"5632","DOI":"10.3390\/jcm10235632","article-title":"Development and Validation of a Post-Operative Non-Union Risk Score for Subtrochanteric Femur Fractures","volume":"10","author":"M. Panteli","year":"2021","journal-title":"J Clin Med"},{"issue":"3","key":"ref20","doi-asserted-by":"publisher","first-page":"591","DOI":"10.12669\/pjms.323.9897","article-title":"Nonunion of subtrochanteric fractures: Comminution or Malreduction","volume":"32","author":"S. H. Park","year":"2016","journal-title":"Pak J Med Sci"},{"issue":"12","key":"ref21","doi-asserted-by":"publisher","first-page":"1910","DOI":"10.1016\/j.injury.2013.08.013","article-title":"Open reduction and intramedullary stabilisation of subtrochanteric femur fractures: A retrospective study of 56 cases","volume":"44","author":"D. M. 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Shukla","year":"2007","journal-title":"Injury"}],"container-title":["Orthopedic Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/166437-does-cephalomedullary-nail-design-influence-risk-of-varus-collapse-in-subtrochanteric-femur-fractures","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T13:51:16Z","timestamp":1786369876000},"score":1,"resource":{"primary":{"URL":"https:\/\/orthopedicreviews.openmedicalpublishing.org\/article\/166437-does-cephalomedullary-nail-design-influence-risk-of-varus-collapse-in-subtrochanteric-femur-fractures"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,10]]},"references-count":31,"URL":"https:\/\/doi.org\/10.52965\/001c.166437","relation":{},"ISSN":["2035-8164"],"issn-type":[{"value":"2035-8164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,10]]}}}