{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:46:34Z","timestamp":1791909994620,"version":"4.3.4"},"reference-count":16,"publisher":"Open Medical Publishing","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Objective<\/jats:title>\n To describe the arthroscopic double-row suture bridge technique for the treatment of large rotator cuff tears augmented with platelet-rich fibrin (PRF).<\/jats:p>\n <\/jats:sec>\n \n Background<\/jats:title>\n Large rotator cuff tears are associated with a high retear rate because of poor tendon quality and extensive tissue defects. Platelet-rich fibrin (PRF) provides a stable fibrin scaffold enriched with multiple growth factors, including transforming growth factor-beta 1 (TGF-\u03b21), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), insulin-like growth factor (IGF), and epidermal growth factor (EGF). These biological mediators have been shown in animal studies to accelerate tendon-to-bone healing.<\/jats:p>\n <\/jats:sec>\n \n Surgical Technique<\/jats:title>\n This case report presents the step-by-step surgical technique, including autologous platelet-rich fibrin (PRF) preparation, arthroscopic evaluation of intra-articular pathology, preparation of the tendon-to-bone footprint, anchor placement, application of PRF at the tendon\u2013bone interface, and rotator cuff repair using the suture bridge technique.<\/jats:p>\n <\/jats:sec>\n \n Clinical Significance<\/jats:title>\n The addition of PRF during arthroscopic repair of large rotator cuff tears may provide a favorable biological environment, promote early angiogenesis, and enhance tendon-to-bone healing during the early postoperative period.<\/jats:p>\n <\/jats:sec>\n \n Disclaimer<\/jats:title>\n This research was funded by the Vietnam National University, Hanoi, under research project No.\u00a0QG.24.109.<\/jats:p>\n <\/jats:sec>","DOI":"10.52965\/001c.170936","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:54:46Z","timestamp":1791906886000},"source":"Crossref","is-referenced-by-count":0,"title":["ARTHROSCOPIC REPAIR OF A LARGE ROTATOR CUFF TEAR USING THE SUTURE BRIDGE TECHNIQUE AUGMENTED WITH PLATELET-RICH FIBRIN: A CASE REPORT"],"prefix":"10.52965","volume":"18","author":[{"given":"Manh Khanh","family":"Nguyen","sequence":"first","affiliation":[{"name":"Vietnam National University, Hanoi, Vietnam","department":["University of Medicine and Pharmacy"]},{"id":[{"id":"https:\/\/ror.org\/049ymah45","id-type":"ROR","asserted-by":"publisher"}],"name":"Viet Duc Hospital","department":["Upper Extremities Surgery and Sport Medicine Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Van Hai","family":"Do","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/049ymah45","id-type":"ROR","asserted-by":"publisher"}],"name":"Viet Duc Hospital","department":["Upper Extremities Surgery and Sport Medicine Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"30777","published-online":{"date-parts":[[2026,10,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/00001721-199302000-00018","article-title":"The cleavage sequence of fibrinopeptide A from fibrinogen fragment E by thrombin, atroxin or batroxobin","volume":"4","author":"D. 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