{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T10:36:06Z","timestamp":1776508566435,"version":"3.51.2"},"reference-count":53,"publisher":"Open Medical Publishing","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":" Introduction<\/jats:title> Posterior tarsal tunnel syndrome involves entrapment of the posterior tibial nerve as it travels in the groove posterior to the medial malleolus. Conventional wisdom dictates that patients with tarsal tunnel syndrome be treated with conservative treatment and medical management, with surgical options available for patients with refractory symptoms and good candidacy. Minimally invasive options for neuropathic entrapment syndromes have developed in recent years and may provide a therapeutic role in tarsal tunnel syndrome.<\/jats:p> <\/jats:sec> Objective<\/jats:title> The present investigation provides a summary of the current state of knowledge on tarsal tunnel syndrome and a comparison between minimally invasive and surgical treatment options.<\/jats:p> <\/jats:sec> Methods<\/jats:title> The literature search was performed in Mendeley. Search fields were varied until redundant. All articles were screened by title and abstract and a preliminary decision to include an article was made. A full-text screening was performed on the selected articles. Any question regarding the inclusion of an article was discussed by 3 authors until an agreement was reached.<\/jats:p> <\/jats:sec> Results<\/jats:title> Most commonly tarsal tunnel syndrome is idiopathic. Other reported causes include post-traumatic, lipomas, cysts, ganglia, schwannomas, ganglia, varicose plantar veins, anatomic anomalies, and systematic inflammatory conditions. Several risk factors have been described including female gender, athletic participation, hypothyroidism, diabetes mellitus, systemic sclerosis, chronic renal failure, and hemodialysis use. A few recent studies demonstrate anatomic variants that have not previously been summarized. Three articles describe clinical outcomes after conservative treatment with acceptable results for first line treatment. Two primary articles report on the use of minimally invasive treatment for tarsal tunnel syndrome. Fourteen articles report on the clinical outcomes after surgical management.<\/jats:p> <\/jats:sec> Conclusion<\/jats:title> Clinical understanding of tarsal tunnel syndrome has evolved significantly, particularly with regards to the pathoanatomy of the tarsal canal over the past twelve years. A few novel anatomic studies shed light on variants that can be helpful in diagnosis. Conservative management remains a good option that can resolve the symptoms of many patients. As more prospective cohorts and clinical trials are performed on minimally invasive options, pulsed radiofrequency and neuromodulation may evolve to play a larger role in the treatment of this condition. Currently, surgical treatment is only pursued in a very select group of patients with refractory symptoms that do not respond to medical or minimally invasive options. Surgical outcomes in the literature are good and current evidence is stronger than that for minimally invasive options.<\/jats:p> <\/jats:sec>","DOI":"10.52965\/001c.37539","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T19:42:35Z","timestamp":1662406955000},"source":"Crossref","is-referenced-by-count":12,"title":["Clinical Results Following Conservative Management of Tarsal Tunnel Syndrome Compared With Surgical Treatment: A Systematic Review"],"prefix":"10.52965","volume":"14","author":[{"given":"Neeraj","family":"Vij","sequence":"first","affiliation":[{"name":"University of Arizona College of Medicine - Phoenix"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather N.","family":"Kaley","sequence":"additional","affiliation":[{"name":"Creighton University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter P.","family":"Issa","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Shreveport School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan D.","family":"Kaye","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology","department":["Louisiana State University"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Viswanath","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Shreveport, Department of Anesthesiology; Creighton University School of Medicine, Department of Anesthesiology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Urits","sequence":"additional","affiliation":[{"name":"Louisiana State University Health Shreveport","department":["Department of Anesthesiology"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"30777","published-online":{"date-parts":[[2022,9,5]]},"reference":[{"issue":"2","key":"ref1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.2214\/ajr.155.2.2115260","article-title":"MR imaging of the tarsal tunnel and related spaces: Normal and abnormal findings with anatomic correlation.","volume":"155","author":"S J Erickson","year":"1990","journal-title":"American Journal of Roentgenology","ISSN":"https:\/\/id.crossref.org\/issn\/0361-803X","issn-type":"print"},{"issue":"1","key":"ref2","article-title":"Tarsal tunnel syndrome in athletes - Analysis of surgical treatment results","volume":"37","author":"P. 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