{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:55:22Z","timestamp":1777578922765,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2011,3,28]],"date-time":"2011-03-28T00:00:00Z","timestamp":1301270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To report outcomes of deep sclerectomy augmented with mitomycin C (MMC) in eyes with raised intraocular pressure (IOP) secondary to uveitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>This was a retrospective case series of 26 eyes of 26 patients with uveitic glaucoma. Mitomycin C 0.2\u20130.4 mg\/mL was applied subconjunctivally prior to scleral flap dissection for 2\u20133 minutes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Mean follow-up was 46.5\u00b122 months (range 12\u201383). Fifteen eyes (58%) had previous intraocular surgery. Preoperative IOP was 33\u00b112 mmHg. Intraocular pressure at 1, 2, and 3 years after surgery was 13\u00b14 mmHg, 13\u00b14 mmHg, and 14\u00b14 mmHg, respectively. The probability of IOP &lt;21 and 18 mmHg with needle revision and laser goniopuncture but without medications or further glaucoma procedure was 89% and 84%, respectively, at 3 years. The cumulative probability for performing laser goniopuncture was 42% at 1 year, 50% at 2 years, and 64% at 3 years. Needle revision was performed in 6 eyes (23%). Three (12%) patients required further glaucoma surgery. The number of glaucoma medications decreased from 3.3\u00b11.2 to 0.3\u00b10.8 by last follow-up (p&lt;0.001). Four eyes (15%) were on medications to control IOP Intraoperative perforation of trabeculo-Descemetic membrane occurred in 3 eyes (12%) and late iris entrapment in perforation or goniopuncture in 4 eyes (15%). Recurrence of uveitis was seen in 11 eyes (42%) with no loss in IOP control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions.<\/jats:title>\n                    <jats:p>Deep sclerectomy with MMC appears to be a safe and effective procedure to lower IOP in uveitic glaucoma with a low rate of complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.2011.6487","type":"journal-article","created":{"date-parts":[[2011,3,28]],"date-time":"2011-03-28T11:58:58Z","timestamp":1301313538000},"page":"708-714","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Deep Sclerectomy with Mitomycin C for Glaucoma Secondary to Uveitis"],"prefix":"10.1177","volume":"21","author":[{"given":"Nitin","family":"Anand","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Calderdale and Huddersfield NHS Trust, West Yorkshire - 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