{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:56:17Z","timestamp":1777578977304,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,6,28]],"date-time":"2011-06-28T00:00:00Z","timestamp":1309219200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To report a case of choroidal melanoma in which the absence of\n                      <jats:sup>18<\/jats:sup>\n                      FDG-positron emission tomography (PET)\/computed tomography (CT) uptake in the whole body scan excluded the presence of any foci of metastases. Additionally, the PET\/CT study correctly diagnosed the necrotic character of the lesion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 76-year-old woman with neovascular glaucoma, and without vitreous or retina visualization, was studied by our ophthalmology service.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ocular ultrasound showed an 18 \u00d7 16 mm vitreous exophytic image compatible with choroidal melanoma; magnetic resonance gave a 17 \u00d7 15 mm exophytic image, highly intense at T1 and hypointense at T2, with cystic and necrotic images after a contrast injection. An\n                      <jats:sup>18<\/jats:sup>\n                      FDG-PET\/CT study revealed a clearly hypometabolic lesion, representing absence of cell viability and excluding active melanoma cells. No other uptake lesions were detected at the whole-body PET\/CT scan, assuming the absence of extraocular metastases. The eye was enucleated, and the pathology study showed a 16 \u00d7 15 mm necrotic choroidal melanoma.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:sup>18<\/jats:sup>\n                      FDG-PET\/CT study correctly depicted the necrotic character of the choroidal melanoma and was able to exclude other foci of metastases.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000016","type":"journal-article","created":{"date-parts":[[2011,6,28]],"date-time":"2011-06-28T13:05:46Z","timestamp":1309266346000},"page":"288-292","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["<sup>18<\/sup>\n                    FDG-PET\/CT Assessing the Absence of Cell Viability and Excluding Metastatic Disease in a Case of Necrotic Choroidal Melanoma"],"prefix":"10.1177","volume":"22","author":[{"given":"Pedro","family":"Romero-Aroca","sequence":"first","affiliation":[{"name":"Ophthalmic Service, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Montero-Jaime","sequence":"additional","affiliation":[{"name":"Radiology Service, CRC-Dimatge, Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Intriago","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, CRC-Dimatge, Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Riu","sequence":"additional","affiliation":[{"name":"Pathology Service, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla B.","family":"Pe\u00f1a-Gonzalez","sequence":"additional","affiliation":[{"name":"Pathology Service, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias","family":"Almena-Garcia","sequence":"additional","affiliation":[{"name":"Ophthalmic Service, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Hospital Universitario Sant Joan, Universidad Rovira i Virgili, Reus - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,6,28]]},"reference":[{"key":"bibr1-ejo.5000016","first-page":"4S","volume":"45","author":"Townsend D.","year":"2004","journal-title":"J Nucl Med"},{"key":"bibr2-ejo.5000016","first-page":"173","volume":"43","author":"Higashi T.","year":"2002","journal-title":"J Nucl Med"},{"key":"bibr3-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2004.09.011"},{"key":"bibr4-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.02.051"},{"key":"bibr5-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0b013e3283403d6c"},{"key":"bibr6-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1159\/000050851"},{"key":"bibr7-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.066399"},{"key":"bibr8-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(79)90060-6"},{"key":"bibr9-ejo.5000016","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-006-0404-3"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ejo.5000016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/ejo.5000016","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ejo.5000016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:36:21Z","timestamp":1777404981000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/ejo.5000016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,28]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.5301\/ejo.5000016"],"URL":"https:\/\/doi.org\/10.5301\/ejo.5000016","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,28]]}}}