{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:55:59Z","timestamp":1777578959539,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,2,9]],"date-time":"2011-02-09T00:00:00Z","timestamp":1297209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess the relationship of ocular pulse amplitude (OPA), as measured by dynamic contour tonometry (DCT), with structural and functional damage in patients with open-angle glaucoma (OAG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross-sectional, observational study, 242 eyes of 139 patients with OAG underwent Goldmann applanation tonometry (GAT), DCT, central corneal thickness (CCT) measurement, visual fields examination (Octopus, Haag Streit), and complete ophthalmologic examination. Linear regression analysis was used to analyze the effect of OPA, DCT, GAT, and CCT to the mean defect (MD) of the visual fields and to the vertical cup to disc ratio (CDR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ocular pulse amplitude was the only variable that showed a significant association with MD (slope=\u20131.1, p=0.012), in contrast to GAT (p=0.98), DCT (p=0.32), and CCT (p=0.42). Ocular pulse amplitude was also negatively associated with CDR (slope=\u20130.028, p=0.0001). Additional multiple regression analysis revealed that OPA (R2=0.12, r=\u20130.25, slope=\u20130.02, p=0.033), GAT (r=\u20130.27, slope=\u20130.01, p=0.027), and CCT (r=\u20130.18, slope=\u20130.001, p=0.012) were statistically significantly correlated to CDR, while DCT was not (r=\u20130.20, slope=0.003, p=0.46). Ocular pulse amplitude did not differ statistically significantly (p=0.93) between eyes with (2.79\u00b11.42) and without (2.77\u00b11.21) prior trabeculectomy. No statistically significant difference of OPA was observed between diagnosis groups (p=0.255).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Decreased OPA seems to be correlated with increased glaucomatous functional and structural damage in OAG. Assessment of OPA by DCT could therefore serve as an important additional parameter in the evaluation of glaucoma patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000043","type":"journal-article","created":{"date-parts":[[2011,9,15]],"date-time":"2011-09-15T22:24:09Z","timestamp":1316125449000},"page":"111-116","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Decreased Ocular Pulse Amplitude Associated with Functional and Structural Damage in Open-Angle Glaucoma"],"prefix":"10.1177","volume":"22","author":[{"given":"Myron","family":"Kynigopoulos","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Clinic Pallas, Olten - Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Argyrios","family":"Tzamalis","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Clinic Pallas, Olten - Switzerland"},{"name":"2nd Department of Ophthalmology, Papageorgiou General Hospital, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Ntampos","sequence":"additional","affiliation":[{"name":"1st Department of Ophthalmology, AHEPA General Hospital, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki - Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torsten","family":"Schlote","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Clinic Pallas, Olten - Switzerland"},{"name":"Outpatient Clinic of Ophthalmology Ambimed, Basel - Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,2,9]]},"reference":[{"key":"bibr1-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00223-2"},{"key":"bibr2-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00272-4"},{"key":"bibr3-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.701"},{"key":"bibr4-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.714"},{"key":"bibr5-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.9.981"},{"key":"bibr6-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1995.01100020100038"},{"key":"bibr7-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1159\/000027250"},{"key":"bibr8-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00074-9"},{"key":"bibr9-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2006.093633"},{"key":"bibr10-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.03.016"},{"key":"bibr11-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.12.1819"},{"key":"bibr12-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00138-X"},{"key":"bibr13-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.6.805"},{"key":"bibr14-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000176936.16015.4e"},{"key":"bibr15-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.075580"},{"key":"bibr16-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-004-1024-6"},{"key":"bibr17-ejo.5000043","first-page":"1389","volume":"43","author":"Bhan A.","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bibr18-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(98)00037-8"},{"key":"bibr19-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(02)00008-3"},{"key":"bibr20-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31815c5f2c"},{"key":"bibr21-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31806ab2fe"},{"key":"bibr22-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-007-0706-2"},{"key":"bibr23-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0018"},{"key":"bibr24-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000196655.85460.d6"},{"key":"bibr25-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-4-4"},{"key":"bibr26-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.032110"},{"key":"bibr27-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.82.7.731"},{"key":"bibr28-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(94)90067-1"},{"key":"bibr29-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1177\/112067210901900410"},{"key":"bibr30-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-005-0065-9"},{"key":"bibr31-ejo.5000043","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-3712"}],"container-title":["European Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ejo.5000043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/ejo.5000043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ejo.5000043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:36:17Z","timestamp":1777404977000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/ejo.5000043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,9]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.5301\/ejo.5000043"],"URL":"https:\/\/doi.org\/10.5301\/ejo.5000043","relation":{},"ISSN":["1120-6721","1724-6016"],"issn-type":[{"value":"1120-6721","type":"print"},{"value":"1724-6016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,9]]}}}