{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:03:32Z","timestamp":1777579412947,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe the antibacterial activity of treatment with riboflavin and ultraviolet A light (UVA) in cases of severe infectious keratitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was performed of an interventional case series in which 6 eyes of 6 patients with severe infectious keratitis, all of whom were refractive to multidrug conventional therapy, were treated with riboflavin\/UVA. The procedure was conducted according to the standardized protocol of corneal collagen crosslinking (CXL) for keratoconus. Best spectacle-corrected visual acuity and clinical outcomes were evaluated before and during the follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Five of the 6 patients showed rapid reduction in symptoms and decreased infiltrate size after riboflavin\/UVA photochemical therapy. Signs of infection and inflammation mostly resolved within 1 to 2 weeks after the treatment. Despite this therapy, one patient continued to deteriorate, and penetrating keratoplasty was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The adjunctive use of riboflavin\/UVA photochemical therapy has a positive effect on refractory infectious keratitis. The treatment seems to be safe and effective and should be considered as part of the first-line therapy in severe cases of infectious keratitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000330","type":"journal-article","created":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T11:23:45Z","timestamp":1375442625000},"page":"21-28","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Riboflavin\/UVA Photochemical Therapy for Severe Infectious Keratitis"],"prefix":"10.1177","volume":"24","author":[{"given":"Alon","family":"Skaat","sequence":"first","affiliation":[{"name":"The Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer - Israel"},{"name":"Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv - Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Zadok","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine, 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