{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:16:23Z","timestamp":1777580183507,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T00:00:00Z","timestamp":1453939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate anterior segment parameters in patients with neurofibromatosis type 1 (NF1) in comparison to healthy individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 34 eyes from 17 patients with NF1 and 34 eyes from 17 age- and sex-matched healthy individuals were included in this study. Each participant underwent a comprehensive ophthalmic assessment including best-corrected visual acuity, slit-lamp biomicroscopy, stereoscopic fundus examination, and intraocular pressure. Central corneal thickness, corneal volume, corneal curvatures (K1 and K2), anterior chamber depth, anterior chamber volume, iridocorneal angle, and pupil size values were measured by Pentacam Scheimpflug camera.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean anterior chamber depth, iridocorneal angle, and anterior chamber volume measurements revealed signi\ufb01cantly lower values when compared with the control group (p&lt;0.001, p&lt;0.001, and p = 0.041, respectively). However, the mean pupil size was significantly larger when compared with the control group (p = 0.008). Central corneal thickness, corneal volume, K1, and K2 values were similar between the study and control groups (p = 0.875, p = 0.549, p = 0.066, and p = 0.166, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results reveal that NF1 is associated with statistically signi\ufb01cant alterations in anterior chamber depth, iridocorneal angle, anterior chamber volume, and pupil size in patients with NF1 when compared with healthy controls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000756","type":"journal-article","created":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T04:49:15Z","timestamp":1454302155000},"page":"564-567","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of Anterior Segment Parameters in Patients with Neurofibromatosis Type 1"],"prefix":"10.1177","volume":"26","author":[{"given":"Necati","family":"Duru","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emre","family":"G\u00f6kta\u015f","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe","family":"\u00d6zk\u00f6se","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynep","family":"Duru","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"Altunel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Ata\u015f","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emin","family":"\u00d6zl\u00fc","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Kayseri Education and Research Hospital, Kayseri - Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,1,28]]},"reference":[{"key":"bibr1-ejo.5000756","unstructured":"Von RecklinghausenF Ueber die multiplen Fibrome der Haut und ihre Beziehung zu den multiplen Neuromen: Festschrift zur Feier des f\u00fcnfundzwanzigj\u00e4hrigen Bestehens des Pathologischen Instituts zu Berlin; Herrn Rudolf Virchow dargebracht. Berlin A. Hirschwald 1882."},{"issue":"5","key":"bibr2-ejo.5000756","first-page":"575","volume":"45","year":"1988","journal-title":"Neurofibromatosis. Conference statement. Arch Neurol"},{"key":"bibr3-ejo.5000756","unstructured":"HusonSM HughesRA The Neurofibromatoses: A Pathogenetic and Clinical Overview. London Chapman & Hall Medical 1994:253-274."},{"key":"bibr4-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90252-A"},{"key":"bibr5-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02716-1"},{"key":"bibr6-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.71.3.235"},{"key":"bibr7-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(81)35034-9"},{"issue":"4","key":"bibr8-ejo.5000756","first-page":"56","volume":"52","author":"Cri\u015fan M","year":"2008","journal-title":"Markers for a non-invasive diagnosis in Recklinghausen neurofibromatosis.] Oftalmologia"},{"key":"bibr9-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2005.12.103"},{"key":"bibr10-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196605)19:5<699::AID-CNCR2820190516>3.0.CO;2-H"},{"key":"bibr11-ejo.5000756","first-page":"1453","volume":"2","author":"Waardenburg PJ","year":"1918","journal-title":"Ned Tijdschr Geneeskd"},{"key":"bibr12-ejo.5000756","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.00915.x"},{"issue":"10","key":"bibr13-ejo.5000756","first-page":"1635","volume":"100","author":"Perry HD","year":"1982","journal-title":"Electron microscopic confirmation of their melanocytic origin. 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