{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:16:16Z","timestamp":1777580176156,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2016,5,3]],"date-time":"2016-05-03T00:00:00Z","timestamp":1462233600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and EXG (108 eyes). Postoperative IOP was the main outcome measurement. We recorded complete and qualified surgical success, need for YAG-laser goniopuncture, and need for postoperative glaucoma medication. We studied factors related to outcome of surgery in a Cox regression model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In the POAG group, the mean (SD) IOP decreased from 22.6 (5.1) mm Hg preoperatively to 16.8 (7.5) mm Hg, with qualified success achieved in 70% of eyes. Postoperatively, 57% were without medication. In the EXG group, IOP decreased from 25.5 (6.5) mm Hg preoperatively to 16.5 (7.8) mm Hg postoperatively, with qualified success achieved in 66% of eyes. Postoperatively, 50% were without medication. Decrease in IOP was statistically significant in both groups (p&lt;0.001). In the POAG group, 12%, and in the EXG group, 24% needed a reoperation in the follow-up period (p = 0.037). In the Cox regression model, 1 week IOP between 2 and 14 mm Hg without medication lowered the hazard rate of losing complete success by 34% (p = 0.031) and the hazard rate of losing qualified success by 54% (p = 0.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The IOP 1 week postoperatively seems to be a prominent indicator of surgical success. Deep sclerectomy is effective in reducing IOP in POAG and EXG subgroups, with reoperations more common in EXG eyes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000762","type":"journal-article","created":{"date-parts":[[2016,3,10]],"date-time":"2016-03-10T05:35:33Z","timestamp":1457588133000},"page":"568-574","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Deep Sclerectomy in Primary Open-Angle Glaucoma and Exfoliative Glaucoma"],"prefix":"10.1177","volume":"26","author":[{"given":"Sakari M.A.","family":"Suominen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Helsinki University Central Hospital, Helsinki - Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika P.","family":"Harju","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Helsinki University Central Hospital, Helsinki - Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eija T.","family":"Vesti","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Turku University Central Hospital, Helsinki - Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,5,3]]},"reference":[{"key":"bibr1-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01032-X"},{"key":"bibr2-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e318182ed9e"},{"key":"bibr3-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2009.01623.x"},{"key":"bibr4-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)80079-0"},{"key":"bibr5-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00263-3"},{"key":"bibr6-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000137869.18156.81"},{"key":"bibr7-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-200206000-00009"},{"key":"bibr8-ejo.5000762","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1755-3768.1988.tb02642.x","volume":"184","author":"Krause U","year":"1988","journal-title":"Acta Ophthalmol Suppl"},{"key":"bibr9-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.117.10.1319"},{"key":"bibr10-ejo.5000762","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2007.01051.x"},{"issue":"2","key":"bibr11-ejo.5000762","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3928\/1542-8877-19970201-05","volume":"28","author":"Konstas AGP","year":"1997","journal-title":"Ophthalmic Surg Lasers"},{"issue":"11","key":"bibr12-ejo.5000762","first-page":"1965","volume":"114","author":"Leske MC","year":"2007","journal-title":"Predictors of long-term progression in the early manifest glaucoma trial. 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