{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:47:54Z","timestamp":1791960474279,"version":"4.3.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,7,16]],"date-time":"2016-07-16T00:00:00Z","timestamp":1468627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the optic nerve head parameters and peripapillary retinal nerve fiber layer using spectral-domain optical coherence tomography (SD-OCT) in a systemic sclerosis (SSc) cohort and age-matched controls to determine whether SSc patients have an increased risk of normal-tension glaucoma (NTG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We examined 30 patients (3 male, 27 female) with SSc and 28 age- and sex-matched controls. Retinal nerve fiber and optic disc morphology were evaluated using Cirrus SD-OCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Optic disc morphology measurements including disc area, rim area, average and vertical cup\/disc (C\/D) ratio, and cup volume were not significantly different between the study groups. The average and 4-quadrant retinal nerve fiber layer (RNFL) measurements of the C\/D &gt;0.3 subgroups were not significantly different in the patients and controls. These values were also similar for the C\/D &gt;0.5 subgroups except that the average inferior quadrant RNFL thickness of the right eyes in the patient subgroup was significantly thinner than in the control subgroup (p&lt;0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our SSc cohort had relatively shorter disease duration but increased prevalence of early glaucomatous damage signs. Our findings indicate that SSc is a risk factor for developing normal-tension glaucoma. Further studies combined with visual field evaluation are necessary to identify the long-term glaucomatous effects of SSc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000827","type":"journal-article","created":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T04:18:06Z","timestamp":1469420286000},"page":"281-284","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Retinal Nerve Fiber and Optic Disc Morphology Using Spectral-Domain                     Optical Coherence Tomography in Scleroderma Patients"],"prefix":"10.1177","volume":"27","author":[{"given":"Sevinc","family":"Sahin-Atik","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Ataturk\r                Teaching and Research Hospital, Yesilyurt, Izmir - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feray","family":"Koc","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ataturk\r                Teaching and Research Hospital, Yesilyurt, Izmir - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirin","family":"Akin-Sari","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Bigadic\r                Public Hospital, Balikesir - Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Ozmen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of\r                Rheumatology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir -\r                Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,16]]},"reference":[{"key":"bibr1-ejo.5000827","doi-asserted-by":"publisher","DOI":"10.2174\/1381612821666150316120338"},{"key":"bibr2-ejo.5000827","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.53"},{"issue":"8","key":"bibr3-ejo.5000827","first-page":"1105","volume":"26","author":"Phelps CD","year":"1985","journal-title":"A case-control study. 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