{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:14:41Z","timestamp":1789546481790,"version":"build-2803163510"},"reference-count":18,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,10,6]],"date-time":"2017-10-06T00:00:00Z","timestamp":1507248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To analyze demographic, clinical, and keratometric outcomes of the second eye in keratoconic patients when the first eye has already been grafted, initially and finally at 12 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective analysis of initial and 12 years visual and keratometric outcomes of the second eye in keratoconic patients when the first one has already been grafted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 107 patients were included: 66 patients were analyzed at the beginning of the follow-up and at 12 years. There were no statistically significant differences with regard to the correction method from the beginning to the end of the follow-up; 3% of patients underwent crosslinking and 4.5% an intracorneal ring segments implantation. There was no significant progress in corneal opacities (1.5% vs 3.0% at 12 years) or visual comfort (90.9% vs 87.9%). The mean values of best-corrected visual acuity (BCVA) (0.69 vs 0.71 at 12 years, on a decimal scale), cylinder (-2.64 D vs -3.13 D), spherical equivalent, and keratometry (46.34 D vs. 46.49 D) had not significantly changed during the follow-up period. During the follow-up, 41 patients (38.3%) received a penetrating or lamellar keratoplasty on the contralateral eye (63% in the 5 years after the first corneal graft). At the time of the keratoplasty procedure, corneal opacities were seen in 7 patients (17.1%), mean BCVA was 0.26 \u00b1 0.16, spherical equivalent mean was -3.70 D, mean cylinder was 3.89 D, mean keratometry values were 52.65 \u00b1 6.80 D, and mean pachymetry value was 335.50 \u00b5m.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study suggests that the period of risk of keratoplasty in the second eye is significant in the first 5 years following the first keratoplasty. New therapeutic treatments have been made available, allowing for stabilization of the keratoconus decreasing the impact of transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ejo.5000996","type":"journal-article","created":{"date-parts":[[2017,6,16]],"date-time":"2017-06-16T08:38:46Z","timestamp":1497602326000},"page":"19-24","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Visual outcomes of the second eye in keratoconic patients who have a corneal graft in the first eye: analysis at 12 years"],"prefix":"10.1177","volume":"28","author":[{"given":"Anne-Sophie","family":"Gauthier","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Besan\u00e7on - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Friot","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Besan\u00e7on - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Puyraveau","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Franche-Comt\u00e9, Besan\u00e7on - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaud","family":"Garcin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Saint-Etienne - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maher","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Besan\u00e7on - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillipe","family":"Gain","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Saint-Etienne - France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Delbosc","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital, Besan\u00e7on - 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