{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:59:19Z","timestamp":1777676359535,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["HIP International"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This study aimed to describe the epidemiology of the causative organism in a series of primary hip arthroplasties revised for a diagnosis of periprosthetic joint infection (PJI) in England and Wales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patient data from the National Joint Registry (NJR) was linked to microbiology data held by Public Health England (PHE) which identified a series of 248 primary hip arthroplasties revised for PJI between 2003 and 2014. Definitive cultures, isolated at time of revision surgery, were available for all cases. Total hip arthroplasty (n = 239, 96%) and hip resurfacing (n = 5, 2%) were the most commonly performed primary procedures. A two-stage revision was the most common operative management (n = 174, 70%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>202 (81%) cases were infected with a single genus microorganism and the most commonly implicated genus was Staphylococcus species (70% of all single genus infections). Staphylococcus species were also the most commonly identified microorganism in mixed genus infections (74% of patient's cultures). There was a significant difference in microorganism distribution when comparing uncemented vs cement implant fixation, with a higher incidence of Gram-negative infection observed in the uncemented group (p = 0.048, Chi-square).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both prophylactic and therapeutic antibiotic regimes should be focused on targeting Staphylococci.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/hipint.5000313","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T06:11:53Z","timestamp":1454047913000},"page":"82-89","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Analysis of Causative Microorganism in 248 Primary Hip Arthroplasties                     Revised for Infection: A Study Using the NJR Dataset"],"prefix":"10.1177","volume":"26","author":[{"given":"Richard J.","family":"Holleyman","sequence":"first","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle\r                University, Newcastle upon Tyne - UK"},{"name":"Health Education North East, Newcastle\r                upon Tyne - UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul N.","family":"Baker","sequence":"additional","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle\r                University, Newcastle upon Tyne - UK"},{"name":"Department of Trauma and Orthopaedics,\r                James Cook University Hospital, Middlesbrough - UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Charlett","sequence":"additional","affiliation":[{"name":"Centre for Infectious Disease\r                Surveillance and Control, Public Health England, London - UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Gould","sequence":"additional","affiliation":[{"name":"Newcastle Public Health Laboratory,\r                Public Health England, Freeman Hospital, Newcastle upon Tyne - UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Deehan","sequence":"additional","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle\r                University, Newcastle upon Tyne - UK"},{"name":"Department of Trauma and Orthopaedics,\r                Freeman Hospital, Newcastle upon Tyne - UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,1,27]]},"reference":[{"key":"bibr1-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.88B7.17150"},{"key":"bibr2-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0209-4"},{"key":"bibr3-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B7.14095"},{"key":"bibr4-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200403000-00005"},{"key":"bibr5-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2011.09.011"},{"key":"bibr6-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199910000-00008"},{"key":"bibr7-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800560902"},{"issue":"8","key":"bibr8-hipint.5000313","doi-asserted-by":"crossref","first-page":"61.5","DOI":"10.1016\/j.arth.2012.02.022","volume":"27","author":"Kurtz SM","year":"2012","journal-title":"J Arthroplasty"},{"key":"bibr9-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.3109\/00365540903186207"},{"key":"bibr10-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1364102"},{"issue":"8","key":"bibr11-hipint.5000313","first-page":"1746","volume":"87","author":"Bozic KJ","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"bibr12-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000214424.67453.9a"},{"key":"bibr13-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200706000-00010"},{"key":"bibr14-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-2030-8"},{"key":"bibr15-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2011.03.031"},{"key":"bibr16-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-1910-2"},{"key":"bibr17-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1016\/j.jotr.2011.07.001"},{"key":"bibr18-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.E.00004"},{"key":"bibr19-hipint.5000313","author":"Holleyman RJ","year":"2015","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"bibr20-hipint.5000313","first-page":"pp1","year":"2014","journal-title":"Annual Report"},{"key":"bibr21-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-012-2090-7"},{"key":"bibr22-hipint.5000313","unstructured":"National Joint Registry\n                        for England, Wales and Northern Ireland. 11\n                      th\n                      Annual\n                        Report, 2014 pp1\u2013135"},{"key":"bibr23-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1086\/605593"},{"key":"bibr24-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2011.03.044"},{"key":"bibr25-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2004.04.006"},{"key":"bibr26-hipint.5000313","doi-asserted-by":"publisher","DOI":"10.1080\/17453670710015229"}],"container-title":["HIP International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/hipint.5000313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/hipint.5000313","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/hipint.5000313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:18:36Z","timestamp":1777450716000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/hipint.5000313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.5301\/hipint.5000313"],"URL":"https:\/\/doi.org\/10.5301\/hipint.5000313","relation":{},"ISSN":["1120-7000","1724-6067"],"issn-type":[{"value":"1120-7000","type":"print"},{"value":"1724-6067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1]]}}}