{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:52:17Z","timestamp":1791381137105,"version":"4.3.3"},"reference-count":36,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,12,14]],"date-time":"2015-12-14T00:00:00Z","timestamp":1450051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["HIP International"],"published-print":{"date-parts":[[2016,3,23]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sickle cell disease (SCD) affects around 80,000 people in the USA and 12,000 in the UK. Up to 40% of patients will get osteonecrosis of the femoral head. Cemented acetabular components yield poor results with the rate of osteolysis ranging from 13.5 to 46%. We report on a consecutive cohort of patients with SCD who underwent uncemented THA with ceramic-on-ceramic (CoC) bearings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Since 2002 52 primary THAs were carried out in 40 patients. The average age was 36.1 years (17-54). 48 cases had exchange blood transfusion preoperatively and 3 had top-up transfusions. An S-ROM was used in 47 hips a Solutions stem in 4 hips and an AML in 1. It was necessary to drill the femur during 12 hips. There were 5 intra-operative peri-prosthetic fractures. 2 dislocations were observed. 2 superficial infections were detected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All components have in-grown. There have been no cases of radiographic osteolysis, migration or loosening of the hip with average 5-year (2-10.1) follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The combination of a multidisciplinary team approach and uncemented implants, with ceramic-on-ceramic bearings used, has made THA in patients with SCD a safe and reliable procedure in our hospital.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/hipint.5000317","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T08:04:05Z","timestamp":1450771445000},"page":"186-192","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Cementless Total HIP Replacements in Sickle Cell Disease"],"prefix":"10.1177","volume":"26","author":[{"given":"Christopher M.","family":"Jack","sequence":"first","affiliation":[{"name":"University Hospital Southampton, Southampton, Hampshire - UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Howard","sequence":"additional","affiliation":[{"name":"University Hospital Southampton, Southampton, Hampshire - UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad S.","family":"Aziz","sequence":"additional","affiliation":[{"name":"University Hospital Southampton, Southampton, Hampshire - UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Kesse-Adu","sequence":"additional","affiliation":[{"name":"University Hospital Southampton, Southampton, Hampshire - UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus J.","family":"Bankes","sequence":"additional","affiliation":[{"name":"University Hospital Southampton, Southampton, Hampshire - UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,12,14]]},"reference":[{"key":"bibr1-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.06.036673"},{"key":"bibr2-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196951010-00003"},{"key":"bibr3-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252104"},{"key":"bibr4-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200303000-00016"},{"key":"bibr5-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.E.01455"},{"key":"bibr6-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199309000-00018"},{"key":"bibr7-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198870040-00004"},{"key":"bibr8-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197759060-00007"},{"key":"bibr9-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.71B3.2722941"},{"key":"bibr10-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.74B3.1587879"},{"key":"bibr11-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198870060-00009"},{"key":"bibr12-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-007-0069-3"},{"key":"bibr13-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-5403(97)90198-4"},{"key":"bibr14-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-002-0337-5"},{"key":"bibr15-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1054\/arth.2002.31084"},{"key":"bibr16-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2013.03.017"},{"issue":"257","key":"bibr17-hipint.5000317","first-page":"107","author":"Engh CA","year":"1990","journal-title":"Clin Orthop Relat Res"},{"key":"bibr18-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.02116"},{"issue":"228","key":"bibr19-hipint.5000317","first-page":"105","author":"Hodgkinson JP","year":"1988","journal-title":"Clin Orthop Relat Res"},{"key":"bibr20-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197355080-00006"},{"key":"bibr21-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61029-X"},{"key":"bibr22-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.K.00697"},{"key":"bibr23-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2493-2"},{"key":"bibr24-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61726-7"},{"key":"bibr25-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1177\/230949900901700321"},{"key":"bibr26-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199911)62:3<129::AID-AJH1>3.0.CO;2-J"},{"key":"bibr27-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.90B4.19718"},{"key":"bibr28-hipint.5000317","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2012.06.021"},{"key":"bibr29-hipint.5000317","unstructured":"Australian Orthopaedic Association National Joint Replacement Registry. 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