{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T23:26:25Z","timestamp":1780788385499,"version":"3.54.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T00:00:00Z","timestamp":1461196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["HIP International"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate mid-term effectiveness of core decompression (CD) followed by injection of bone-marrow concentration (BMC) in osteonecrosis of the femoral head (ONFH) compared with CD alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively studied 60 hips in 45 patients with ONFH Ficat I-II after a mean follow-up of 45 (range 24-171) months. Group A (19 hips) were treated with CD, and Group B (41 hips) with CD plus autologous BMC. Necrotic lesions were classified according to MRI findings in: (i) the lesion angle; and (ii) the relation of the necrotic area to the weight-bearing portion. Outcomes included clinical changes and radiographic femoral head collapse. Risk factors associated with radiological collapse were evaluated by Cox regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Postoperative Merl\u00e9 D'Aubigne and Postel hip score was similar in both groups. Femoral head collapse was observed in 10\/19 hips in Group A and 22\/41 in Group B. At 24 months, the probability of not having a collapse was 56.4% (95% CI, 33.6%-79.1%) for Group A and 57.6% (95% CI, 41.7%-73.4%) for Group B (p = 0.47). The risk of collapse increased in hips with a lesion angle higher than 150\u00b0 (p&lt;0.02, hazard risk [HR] 4.073) in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>With the standard BMC technique performed without monitoring the number of progenitors in the concentrate, we are uncertain to observe a significant decrease in femoral head collapse compared to CD alone. Improved outcomes may require the monitoring of progenitor cells injected into the femoral head, particularly in large lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/hipint.5000366","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T06:12:28Z","timestamp":1461305548000},"page":"432-437","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Mid-Term Comparative Outcomes of Autologous Bone-Marrow Concentration to Treat Osteonecrosis of the Femoral Head in Standard Practice"],"prefix":"10.1177","volume":"26","author":[{"given":"Ana","family":"Cruz-Pardos","sequence":"first","affiliation":[{"name":"Orthopaedic Surgery Department, Hospital La Paz, Madrid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Garcia-Rey","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Hospital La Paz, Madrid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Ortega-Chamarro","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Hospital La Paz, Madrid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Duran-Manrique","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Hospital La Paz, Madrid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Gomez-Barrena","sequence":"additional","affiliation":[{"name":"Orthopaedic Surgery Department, Hospital La Paz, Madrid - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,4,21]]},"reference":[{"key":"bibr1-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5413.45316"},{"key":"bibr2-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.5301\/HIP.2011.8538"},{"key":"bibr3-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5413.45322"},{"key":"bibr4-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.5301\/HIP.2011.8760"},{"key":"bibr5-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200401000-00006"},{"key":"bibr6-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-2050-4"},{"key":"bibr7-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-3220-3"},{"key":"bibr8-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0184-9"},{"key":"bibr9-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00671"},{"key":"bibr10-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.21-2-190"},{"key":"bibr11-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195436030-00001"},{"key":"bibr12-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.67B1.3155745"},{"key":"bibr13-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.77B6.7593098"},{"key":"bibr14-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200302000-00019"},{"key":"bibr15-hipint.5000366","first-page":"331","volume-title":"Annual report of Japanese investigation committee for intractable disease, avascular necrosis of the femoral head.","author":"Ono K.","year":"1987"},{"key":"bibr16-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.73B1.1991778"},{"key":"bibr17-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199707000-00011"},{"key":"bibr18-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200406000-00006"},{"key":"bibr19-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2011.07.032"},{"key":"bibr20-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2011.08.008"},{"key":"bibr21-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-013-2017-z"},{"key":"bibr22-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.3109\/17453670903278241"},{"key":"bibr23-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B7.16289"},{"key":"bibr24-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.01582"},{"key":"bibr25-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.10.817"},{"key":"bibr26-hipint.5000366","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.10.817"}],"container-title":["HIP International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/hipint.5000366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/hipint.5000366","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/hipint.5000366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:18:52Z","timestamp":1777450732000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/hipint.5000366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,21]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.5301\/hipint.5000366"],"URL":"https:\/\/doi.org\/10.5301\/hipint.5000366","relation":{},"ISSN":["1120-7000","1724-6067"],"issn-type":[{"value":"1120-7000","type":"print"},{"value":"1724-6067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,21]]}}}