{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:14:29Z","timestamp":1777677269191,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T00:00:00Z","timestamp":1505952000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["HIP International"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>We investigate the effectiveness of a comprehensive aseptic protocol in reducing surgical site infection (SSI) after hip arthroplasty in a single medical centre with a high prevalence of methicillin-resistant Staphylococcus aureus (MRSA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospectively collected database of all patients undergoing hip arthroplasty in a single centre between 2005 and 2011 was reviewed for SSI using Centers for Disease Control (CDC) criteria and AAOS guidelines. All patients were administered an aseptic protocol consisting of: preoperative 2% mupirocin nasal ointment and 0.4% chlorhexidine surgical-site wipes; modified instrument care; perioperative prophylactic vancomycin and cefazolin; and surgical-site skin preparation with chlorhexidine, alcohol and iodophor. We compare our protocol hip arthroplasty SSI rate to our institutional historical control and to contemporary literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 774 patients, 69% were ASA&gt;2, 45% had BMI\u226530 and 10.3% had rheumatoid arthritis. We found an overall 0.39% infection rate; significantly lower than our institutional historical control (0.39% vs. 2.60%, p&lt;0.001, OR 0.15, NNT 200) and significantly lower than 6 published reports (p&lt;0.001-0.022, OR 0.16-0.22). Compared to these cohorts, significantly more of our patients were ASA&gt;2, had BMI\u226530 or had rheumatoid arthritis. Patients with 3 or more identifiable risk factors were at an increased risk of SSI compared to those with 2 or fewer risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our aseptic protocol decreases SSI in a high-risk population undergoing hip arthroplasty in a medical centre and community with a high prevalence of MRSA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/hipint.5000551","type":"journal-article","created":{"date-parts":[[2017,10,2]],"date-time":"2017-10-02T04:44:58Z","timestamp":1506919498000},"page":"182-188","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Multifaceted aseptic protocol decreases surgical site infections following hip arthroplasty"],"prefix":"10.1177","volume":"28","author":[{"given":"Ryan E.","family":"Harold","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bennet A.","family":"Butler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Lamplot","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago Pritzker School of Medicine, Chicago - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hue H.","family":"Luu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago Pritzker School of Medicine, Chicago - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cort D.","family":"Lawton","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Manning","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago - 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