{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T20:34:17Z","timestamp":1787344457724,"version":"build-2736575974"},"reference-count":25,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,9,10]],"date-time":"2017-09-10T00:00:00Z","timestamp":1505001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["HIP International"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Core decompression (CD) with or without the addition of autologous bone graft (CDBG) is currently the most widely accepted treatment for hip osteonecrosis in stages of pre-collapse. The use of bone marrow mesenchymal stem cells (CDSC) is emerging as a promising biological alternative. We sought to determine the total hip arthroplasty (THA) conversion rate for patients treated with CD, CDBG or CDSC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods:<\/jats:title>\n                    <jats:p>Between 1996 and 2012, 97 cases were evaluated in 72 patients: 47 CD cases, 34 CDGB cases and 16 CDSC cases. The mean age was 39 (20-63) years, 25 bilateral, 19 female and 53 male, 14 Ficat 1 and 83 Ficat 2. Bilateral cases with asymmetric stage and equal treatment were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Conversion rate to THA was 44% for the CD group (21\/47) at an average of 77 (24-324) months; 50% for the CDBG group (17\/34) at an average of 34 (24-240) months and 50% for the CDSC group (8\/16) at an average of 48 (24-72) months (p = 0.619). Log Rank test for survivorship analysis was not significant (p = 0.2011). Immunodeficiency or corticosteroid treatment history was associated with 16\/47 of the CD group, 7\/34 in the CDBG group and 1\/16 in the CDSC group. Trauma was associated with 2\/47 of the CD group, 5\/34 of the CDBG group and none of the CDSC group. Hazard ratio considering risk factors was not significant (p = 0.252).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In these series of cases including patients with pre-collapse osteonecrosis, we observed non-significant results regarding rate of conversion to THA with CD, CDBG or CDSC at an average of 5.5 years.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/hipint.5000552","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T03:52:38Z","timestamp":1507866758000},"page":"189-193","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["THA conversion rate comparing decompression alone, with autologous bone graft or stem cells in osteonecrosis"],"prefix":"10.1177","volume":"28","author":[{"given":"Francisco J.","family":"Nally","sequence":"first","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo","family":"Zanotti","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mart\u00edn A.","family":"Buttaro","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando D.","family":"Dilernia","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio G.","family":"Mansilla","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando M.","family":"Comba","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. Ottolenghi\u201d Orthopaedic and Traumatology Institute, Italian Hospital of Buenos Aires, Buenos Aires - Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Piccaluga","sequence":"additional","affiliation":[{"name":"\u201cSir John Charnley\u201d Hip centre, \u201cCarlos E. 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