{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:21:36Z","timestamp":1783488096632,"version":"3.55.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Artif Organs"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:sec>\n                    <jats:title>Purposes<\/jats:title>\n                    <jats:p>To review patients with a hematogenous and early post-surgical prosthetic joint infection (PJI) due to S. aureus treated with debridement and retention of the implant and to compare their clinical characteristics and outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From January 2000 all patients with a prosthetic joint infection treated in a single-center were prospectively registered and followed-up. All potentially variables associated with outcome were recorded. For the present study, cases with a hematogenous or early post-surgical PJI due to S. aureus treated with debridement and at least 2 years of follow-up were reviewed. Cox regression model to identify factors associated with outcome were applied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>12 hematogenous and 53 early post-surgical PJI due to S. aureus were included. Number of patients presenting with fever, leucocyte count, C-reactive protein concentration, and the number of bacteremic patients were significantly higher in hematogenous infections while the number of polymicrobial infections was lower in hematogenous than in early post-surgical infections. The global failure rate in hematogenous and early post-surgical PJI was 58.7% and 24.5%, respectively (p=0.02). The Cox regression model identified hematogenous infections (OR: 2.57, CI95%: 1.02\u20136.51, p=0.04) and the need of a second debridement (OR: 4.61, CI95%: 1.86\u201311.4, p=0.001) as independent predictors of failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hematogenous infections were monomicrobial and had more severe symptoms and signs of infection than early post-surgical PJI. Hematogenous PJI due to S. aureus, using debridement with implant retention, had a worse outcome than early post-surgical infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5301\/ijao.5000029","type":"journal-article","created":{"date-parts":[[2011,11,20]],"date-time":"2011-11-20T10:40:28Z","timestamp":1321785628000},"page":"863-869","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":62,"title":["Efficacy of Debridement in Hematogenous and Early Post-Surgical Prosthetic Joint Infections"],"prefix":"10.1177","volume":"34","author":[{"given":"F\u00e9lix","family":"Vilchez","sequence":"first","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C.","family":"Mart\u00ednez-Pastor","sequence":"additional","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n","family":"Garc\u00eda-Ramiro","sequence":"additional","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillem","family":"Bori","sequence":"additional","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Tornero","sequence":"additional","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Orthopedics of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Mensa","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Soriano","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases of Hospital Cl\u00ednic of Barcelona, Hospital Cl\u00ednic Universitari, IDIBAPS, Barcelona - Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,11,17]]},"reference":[{"key":"bibr1-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.66B4.6430907"},{"key":"bibr2-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.08.015"},{"key":"bibr3-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1086\/318704"},{"key":"bibr4-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01400.x"},{"key":"bibr5-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra040181"},{"key":"bibr6-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1086\/368182"},{"key":"bibr7-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.5.914"},{"key":"bibr8-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp107"},{"key":"bibr9-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-5403(03)00288-2"},{"key":"bibr10-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1086\/499234"},{"key":"bibr11-ijao.5000029","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/00003086-198911000-00020","volume":"248","author":"Morrey B.F.","year":"1989","journal-title":"Clin Orthop Relat Res."},{"key":"bibr12-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1097\/BLO.0b013e3181123d4e"},{"key":"bibr13-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199604000-00005"},{"key":"bibr14-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1086\/529436"},{"key":"bibr15-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.03.036"},{"key":"bibr16-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1080\/17453670710014527"},{"key":"bibr17-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01378.x"},{"key":"bibr18-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2006.01463.x"},{"key":"bibr19-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.19.1537"},{"key":"bibr20-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01230.x"},{"key":"bibr21-ijao.5000029","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00047-09"}],"container-title":["The International Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ijao.5000029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/ijao.5000029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:41:52Z","timestamp":1777491712000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/ijao.5000029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.5301\/ijao.5000029"],"URL":"https:\/\/doi.org\/10.5301\/ijao.5000029","relation":{},"ISSN":["0391-3988","1724-6040"],"issn-type":[{"value":"0391-3988","type":"print"},{"value":"1724-6040","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}