{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:24:14Z","timestamp":1777983854954,"version":"3.51.4"},"reference-count":59,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Scleroderma and Related Disorders"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p>Digital ulcers (DU) are a common clinical problem in systemic sclerosis (SSc); however, there is no standardization of local wound care protocols for management of these lesions. There is a well-recognized need to develop and standardize non-pharmacological management of DU in patients with SSc, and to adopt these protocols in future clinical trials that focus on DU healing. The purpose of this review is to outline the types of DU that occur in SSc, and provide an update on the principles of wound management for these lesions based on the current literature and expert opinion.<\/jats:p>","DOI":"10.5301\/jsrd.5000268","type":"journal-article","created":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T04:47:45Z","timestamp":1510894065000},"page":"66-70","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Review of local wound management for scleroderma-associated digital ulcers"],"prefix":"10.1136","volume":"3","author":[{"given":"Nicholas","family":"Lebedoff","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy M.","family":"Frech","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA"},{"name":"Division of Rheumatology, Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria K.","family":"Shanmugam","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, The George Washington University School of Medicine and Health Sciences, Washington DC - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryeh","family":"Fischer","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, University of Colorado School of Medicine, Denver, CO - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Erhardt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Kolfenbach","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, University of Colorado School of Medicine, Denver, CO - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Kohler","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Bernhisel","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Department of Surgery, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giavonni M.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Division of General Surgery, Department of Surgery, University of Utah, Salt Lake City, UT - USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,11,17]]},"reference":[{"key":"bibr1-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.2"},{"issue":"12","key":"bibr2-jsrd.5000268","first-page":"2423","volume":"34","author":"Hachulla E","year":"2007","journal-title":"J Rheumatol"},{"key":"bibr3-jsrd.5000268","first-page":"939","volume":"11","author":"Abraham S","year":"2015","journal-title":"Ther Clin Risk Manag"},{"key":"bibr4-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep105"},{"key":"bibr5-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1080\/08916930903002487"},{"key":"bibr6-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kew313"},{"key":"bibr7-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.5301\/jsrd.5000236"},{"key":"bibr8-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-015-8500-0"},{"issue":"4","key":"bibr9-jsrd.5000268","first-page":"S127","volume":"33","author":"Silva I","year":"2015","journal-title":"Clin Exp Rheumatol"},{"key":"bibr10-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-013-2460-7"},{"key":"bibr11-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150061"},{"issue":"5","key":"bibr12-jsrd.5000268","first-page":"100","volume":"100","author":"Murray AK","year":"2016","journal-title":"Clin Exp Rheumatol"},{"key":"bibr13-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2834-5"},{"key":"bibr14-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0558-9"},{"key":"bibr15-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2016.12.008"},{"key":"bibr16-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker414"},{"key":"bibr17-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000332"},{"key":"bibr18-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq097"},{"key":"bibr19-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2014.23.10.510"},{"key":"bibr20-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2016.09.006"},{"key":"bibr21-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2016.21.Sup12.S39"},{"key":"bibr22-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2747"},{"key":"bibr23-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/747946"},{"key":"bibr24-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2015.24.Sup20.S52"},{"issue":"6","key":"bibr25-jsrd.5000268","first-page":"160","volume":"23","author":"Jia S","year":"2011","journal-title":"Wounds"},{"issue":"8","key":"bibr26-jsrd.5000268","first-page":"20","volume":"57","author":"Jia S","year":"2011","journal-title":"Ostomy Wound Manage"},{"issue":"3","key":"bibr27-jsrd.5000268","first-page":"51","volume":"27","author":"Fiori G","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"bibr28-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.Sup3.S7"},{"key":"bibr29-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2014.01.012"},{"key":"bibr30-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000383198.35815.a2"},{"issue":"7","key":"bibr31-jsrd.5000268","first-page":"337","volume":"88","author":"Weeks LE","year":"1990","journal-title":"J Ky Med Assoc"},{"key":"bibr32-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2011.05138.x"},{"key":"bibr33-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2011.87"},{"key":"bibr34-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2014.23.3.93"},{"key":"bibr35-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2008.04923.x"},{"issue":"1","key":"bibr36-jsrd.5000268","first-page":"CD003557","author":"OMeara S","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr37-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000266660.88900.38"},{"issue":"4","key":"bibr38-jsrd.5000268","first-page":"62","volume":"54","author":"Fleming CP.","year":"2008","journal-title":"Ostomy Wound Manage"},{"issue":"1","key":"bibr39-jsrd.5000268","first-page":"ii","volume":"4","author":"Aduba DC","year":"2017","journal-title":"Bioengineering (Basel)"},{"key":"bibr40-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000465301.37313.57"},{"issue":"4","key":"bibr41-jsrd.5000268","first-page":"S153","volume":"33","author":"Willems LM","year":"2015","journal-title":"Clin Exp Rheumatol"},{"key":"bibr42-jsrd.5000268","author":"Kowal-Bielecka O","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"bibr43-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kev201"},{"key":"bibr44-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq291"},{"key":"bibr45-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-207001"},{"key":"bibr46-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.130658"},{"key":"bibr47-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1186\/ar4216"},{"key":"bibr48-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-016-3582-4"},{"key":"bibr49-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1002\/micr.22379"},{"key":"bibr50-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2015.48152"},{"key":"bibr51-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.3727\/096368914X685636"},{"key":"bibr52-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12128"},{"key":"bibr53-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.238.39"},{"key":"bibr54-jsrd.5000268","first-page":"307","volume":"11","author":"Ughi N","year":"2016","journal-title":"Clin Interv Aging"},{"key":"bibr55-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-016-3414-7"},{"key":"bibr56-jsrd.5000268","author":"Shanmugam VK","year":"2016","journal-title":"Wound Repair Regen"},{"key":"bibr57-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12268"},{"key":"bibr58-jsrd.5000268","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e328335a7d2"},{"key":"bibr59-jsrd.5000268","author":"Pauling JD","year":"2017","journal-title":"Clin Exp Rheumatol"}],"container-title":["Journal of Scleroderma and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/jsrd.5000268","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/jsrd.5000268","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/jsrd.5000268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T11:52:42Z","timestamp":1777981962000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/jsrd.5000268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,17]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.5301\/jsrd.5000268"],"URL":"https:\/\/doi.org\/10.5301\/jsrd.5000268","relation":{},"ISSN":["2397-1983","2397-1991"],"issn-type":[{"value":"2397-1983","type":"print"},{"value":"2397-1991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,17]]}}}