{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:37:47Z","timestamp":1762004267164,"version":"3.38.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,1,17]],"date-time":"2011-01-17T00:00:00Z","timestamp":1295222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> Totally implanted vascular (TIVA) ports are used in children for repeated blood samples or intravenous treatments. We have recently published a prospective evaluation of surgical incidents and early complications associated with these devices. This work is the final part of the same study, assessing late complications over a follow-up of 2 yrs. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> From January 2006 to January 2008, children older than 1 yr of age with a diagnosis of solid or blood cell malignancy were included. Insertion technique and care of the device were standardized. Every manipulation was prospectively recorded by specialized nurses. Obstruction was documented clinically. When bacteremia was suspected, routine central and peripheral blood cultures were drawn. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Forty-five consecutive patients were enrolled in the study. Mean age at the time of the procedure was 8.5 yrs. There was no catheter-related infection within the first 4 weeks post-surgery. No device had to be removed because of infection or obstruction during follow-up. Frequent accesses to the port (\u22653 per day over a 10\u2013day period) were associated with an 8\u2013fold risk of infection. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Insertion and use of TIVA devices were frequently associated with complications. No device had to be removed because of infection or obstruction over the follow-up period, although no prophylactic antibiotic agent was used. Restrictive use of antibiotics may prevent opportunistic infection. Frequent access to the device was significantly associated with line infection (odds ratio=8.43). No risk factor was identified for obstruction which occurred at a rate of 5.3 per 10,000 accesses. <\/jats:p><\/jats:sec>","DOI":"10.5301\/jva.2011.6258","type":"journal-article","created":{"date-parts":[[2011,1,17]],"date-time":"2011-01-17T13:31:12Z","timestamp":1295271072000},"page":"207-210","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Frequent Accesses to Totally Implanted Vascular Ports in Pediatric                     Oncology Patients are Associated with Higher Infection Rates"],"prefix":"10.1177","volume":"12","author":[{"given":"Christophe","family":"Gapany","sequence":"first","affiliation":[{"name":"Pediatric Surgery, University Hospital of\r                Geneva and Children's Hospital, Geneva - Switzerland"},{"name":"Pediatric Surgery, Centre Hospitalier\r                Universitaire Vaudois and University of Lausanne, Lausanne - Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Tercier","sequence":"additional","affiliation":[{"name":"Pediatric Surgery, Centre Hospitalier\r                Universitaire Vaudois and University of Lausanne, Lausanne - Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Diezi","sequence":"additional","affiliation":[{"name":"Pediatric Oncology and Hematology Unit,\r                Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne -\r                Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Clement","sequence":"additional","affiliation":[{"name":"Pediatric Oncology and Hematology Unit,\r                Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne -\r                Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katy","family":"Lemay","sequence":"additional","affiliation":[{"name":"Pediatric Oncology and Hematology Unit,\r                Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne -\r                Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marc","family":"Joseph","sequence":"additional","affiliation":[{"name":"Pediatric Surgery, Centre Hospitalier\r                Universitaire Vaudois and University of Lausanne, Lausanne - Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1,17]]},"reference":[{"key":"bibr1-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199910)33:4<377::AID-MPO6>3.0.CO;2-X"},{"key":"bibr2-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.4.1267"},{"key":"bibr3-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1067\/mic.2003.29"},{"key":"bibr4-JVA.2011.6258","first-page":"397","volume":"60","author":"Koolen D.A.","year":"2002","journal-title":"Netherland Journal of Medicine"},{"key":"bibr5-JVA.2011.6258","first-page":"431","volume":"91","author":"Labourey J.L.","year":"2004","journal-title":"Bull Cancer"},{"key":"bibr6-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1097\/00001622-200307000-00002"},{"key":"bibr7-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-001-0330-3"},{"key":"bibr8-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-004-0607-4"},{"key":"bibr9-JVA.2011.6258","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2004.08.041"},{"key":"bibr10-JVA.2011.6258","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/pbc.20588","volume":"45","year":"2005","journal-title":"Abstracts. 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