{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:58:11Z","timestamp":1782939491868,"version":"3.54.5"},"reference-count":41,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Vasc Access"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Home Parenteral Nutrition is a therapeutic option to improve quality of life in chronic intestinal failure. <\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p> To describe frequency of complications both in cancer and non-cancer patients. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> This study was performed on 270 adult patients (52% with cancer, 48% without cancer) followed for a total of 371 years of treatment. Mean duration of therapy was 191\u00b1181 for cancer and 830\u00b11168 days\/patient for non-cancer. The treatment was administered by a competent, dedicated provider. Patients received our prescribed \u201call-in-one admixtures\u201d at their homes. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Catheter-related complications\/1000-days-catheter was 1.40; mechanical complications were comparable in cancer (0.82) and non-cancer (0.91) patients while a statistically significant difference was observed between cancer (0.71) and non-cancer (0.46) patients for sepsis. Bacterial infections were more frequent in non-cancer, mycotic infections primarily affected cancer patients. In our experience 49% of the patients were readmitted, with a low incidence rate of 0.89\/1000 days-catheter. The incidence of hepatobiliary complications in our population was 65%. The degree of liver damage was related to short bowel syndrome and to length of treatment. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> This study indicated that cancer patients are more vulnerable to CVC-related infections during Home Parenteral Nutrition and that a safer Home Parenteral Nutrition protocol should be adopted in order to contain CVC-related complications. <\/jats:p><\/jats:sec>","DOI":"10.5301\/jva.5000133","type":"journal-article","created":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T10:54:28Z","timestamp":1355309668000},"page":"490-497","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Catheter-Related Complications in Long-Term Home Parenteral Nutrition Patients with Chronic Intestinal Failure"],"prefix":"10.1177","volume":"13","author":[{"given":"Francesco William","family":"Guglielmi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nunzia","family":"Regano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Mazzuoli","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Rizzi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Fregnan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Leogrande","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Addante","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Artificial Nutrition, \u201cSan Nicola Pellegrino\u201d Hospital - Trani, (BT) - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Altomarino","family":"Guglielmi","sequence":"additional","affiliation":[{"name":"General Surgery Department II University \u2018Francesco 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